Chemical and biological studies on human oxygenases द्वारा Thinnes, C, Dr Cyrille C. Thinnes

Targeting histone lysine demethylases - Progress, challenges, and the future. द्वारा Thinnes, C, England, K, Kawamura, A, Chowdhury, R, Schofield, C, Hopkinson, R

Inhibition of JMJD6 by 2-oxoglutarate mimics द्वारा Islam, MS, Thinnes, C, Holt-Martyn, J, Chowdhury, R, McDonough, M, Schofield, C

Optimisation of Isoenzyme-Specific Reagents: Organic Synthesis and Biological Characterisation of Naphthoquinones as Selective Inhibitors of Human n-Acetyltransferase 1 (hnat1) and... द्वारा Laurieri, N, Thinnes, C, Westwood, I, Pedro, B, Seden, P, Davies, S, Russell, A, Sim, E

Glucose metabolism and oxygen availability govern reactivation from latency of the human retrovirus HTLV-1 द्वारा Kulkarni, A, Mateeus, M, Thinnes, C, McCullagh, J, Schofield, C, Taylor, G, Bangham, C

Complement C1q is hydroxylated by collagen prolyl 4 hydroxylase, and is sensitive to off target inhibition by prolyl hydroxylase domain inhibitors that stabilise Hypoxia Inducible... द्वारा Kiriakidis, S, Hoer, S, Burrows, N, Biddlecome, G, Khan, M, Thinnes, C, Schofield, C, Rogers, N, Botto, M, Paleolog, E, Maxwell, P

Structure of the ribosomal oxygenase OGFOD1 provides insights into the regio- and stereoselectivity of prolyl hydroxylases द्वारा Horita, S, Scotti, J, Thinnes, C, Taromsari, Y, Thalhammer, A, Ge, W, Aik, W, Loenarz, C, Schofield, C, McDonough, M

Selective inhibitors of a human prolyl hydroxylase (OGFOD1) involved in ribosomal decoding द्वारा Thinnes, C, Lohans, C, Abboud, M, Yeh, T, Tumber, A, Nowak, R, Attwood, M, Cockman, M, Oppermann, U, Loenarz, C, Schofield, C

A novel color change mechanism for breast cancer biomarker detection: naphthoquinones as specific ligands of human arylamine N-acetyltransferase 1 द्वारा Laurieri, N, Egleton, J, Varney, A, Thinnes, C, Quevedo, C, Seden, P, Thompson, S, Rodrigues-Lima, F, Dairou, J, Dupret, J, Russell, A, Sim, E

5-Carboxy-8-hydroxyquinoline is a broad spectrum 2-oxoglutarate oxygenase inhibitor which causes iron translocation द्वारा Hopkinson, R, Tumber, A, Yapp, C, Chowdhury, R, Aik, W, Che, K, Li, X, Kristensen, J, King, O, Chan, M, Yeoh, K, Choi, H, Walport, L, Thinnes, C, Bush, J, Lejeune, C, Rydzik, A, Rose, N, Bagg, E, McDonough, M, Krojer, T, Yue, W, Ng, S, Olsen, L, Brennan, P

Therapeutic targeting of oxygen-sensing prolyl hydroxylases abrogates ATF4-dependent neuronal death and improves outcomes after brain hemorrhage in several rodent models द्वारा Karuppagounder, S, Alim, I, Khim, S, Bourassa, M, Sleiman, S, John, R, Thinnes, C, Yeh, T, Demetriades, M, Neitemeier, S, Cruz, D, Gazaryan, I, Killilea, D, Morgenstern, L, Xi, G, Keep, R, Schallert, T, Tappero, R, Zhong, J, Cho, S, Maxfield, F, Holman, T, Culmsee, C, Fong, G, Su, Y, Ming, G, Song, H, Cave, J, Schofield, C, Colbourne, F, Coppola, G, Ratan, R