Selection on alleles affecting human longevity and late-life disease: the example of apolipoprotein E. by Fotios Drenos, Thomas B L Kirkwood

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Grip Strength Decline and Its Determinants in the Very Old: Longitudinal Findings from the Newcastle 85+ Study. by Antoneta Granic, Karen Davies, Carol Jagger, Thomas B L Kirkwood, Holly E Syddall, Avan A Sayer

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Integrated Stochastic Model of DNA Damage Repair by Non-homologous End Joining and p53/p21-Mediated Early Senescence Signalling. by David W P Dolan, Anze Zupanic, Glyn Nelson, Philip Hall, Satomi Miwa, Thomas B L Kirkwood, Daryl P Shanley

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The personal and health service impact of falls in 85 year olds: cross-sectional findings from the Newcastle 85+ cohort study. by Joanna Collerton, Andrew Kingston, John Bond, Karen Davies, Martin P Eccles, Carol Jagger, Thomas B L Kirkwood, Julia L Newton

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Dynamic modelling of pathways to cellular senescence reveals strategies for targeted interventions. by Piero Dalle Pezze, Glyn Nelson, Elsje G Otten, Viktor I Korolchuk, Thomas B L Kirkwood, Thomas von Zglinicki, Daryl P Shanley

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Comparison of mitochondrial mutation spectra in ageing human colonic epithelium and disease: absence of evidence for purifying selection in somatic mitochondrial DNA point mutation... by Laura C Greaves, Joanna L Elson, Marco Nooteboom, John P Grady, Geoffrey A Taylor, Robert W Taylor, John C Mathers, Thomas B L Kirkwood, Doug M Turnbull

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Predominant Asymmetrical Stem Cell Fate Outcome Limits the Rate of Niche Succession in Human Colonic Crypts by Craig Stamp, Anze Zupanic, Ashwin Sachdeva, Elizabeth A. Stoll, Daryl P. Shanley, John C. Mathers, Thomas B.L. Kirkwood, Rakesh Heer, Benjamin D. Simons, Doug M. Turnbull, Laura C. Greaves

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Reactive oxygen species production and mitochondrial dysfunction in white blood cells are not valid biomarkers of ageing in the very old. by Laura Wiley, Deepthi Ashok, Carmen Martin-Ruiz, Duncan C S Talbot, Joanna Collerton, Andrew Kingston, Karen Davies, Patrick F Chinnery, Michael Catt, Carol Jagger, Thomas B L Kirkwood, Thomas von Zglinicki

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Mitochondrial dysfunction accounts for the stochastic heterogeneity in telomere-dependent senescence. by João F Passos, Gabriele Saretzki, Shaheda Ahmed, Glyn Nelson, Torsten Richter, Heiko Peters, Ilka Wappler, Matthew J Birket, Graham Harold, Karin Schaeuble, Mark A Birch-Machin, Thomas B L Kirkwood, Thomas von Zglinicki

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Publisher Correction: A meta-analysis of genome-wide association studies identifies multiple longevity genes by Joris Deelen, Daniel S. Evans, Dan E. Arking, Niccolò Tesi, Marianne Nygaard, Xiaomin Liu, Mary K. Wojczynski, Mary L. Biggs, Ashley van der Spek, Gil Atzmon, Erin B. Ware, Chloé Sarnowski, Albert V. Smith, Ilkka Seppälä, Heather J. Cordell, Janina Dose, Najaf Amin, Alice M. Arnold, Kristin L. Ayers, Nir Barzilai, Elizabeth J. Becker, Marian Beekman, Hélène Blanché, Kaare Christensen, Lene Christiansen, Joanna C. Collerton, Sarah Cubaynes, Steven R. Cummings, Karen Davies, Birgit Debrabant, Jean-François Deleuze, Rachel Duncan, Jessica D. Faul, Claudio Franceschi, Pilar Galan, Vilmundur Gudnason, Tamara B. Harris, Martijn Huisman, Mikko A. Hurme, Carol Jagger, Iris Jansen, Marja Jylhä, Mika Kähönen, David Karasik, Sharon L. R. Kardia, Andrew Kingston, Thomas B. L. Kirkwood, Lenore J. Launer, Terho Lehtimäki, Wolfgang Lieb, Leo-Pekka Lyytikäinen, Carmen Martin-Ruiz, Junxia Min, Almut Nebel, Anne B. Newman, Chao Nie, Ellen A. Nohr, Eric S. Orwoll, Thomas T. Perls, Michael A. Province, Bruce M. Psaty, Olli T. Raitakari, Marcel J. T. Reinders, Jean-Marie Robine, Jerome I. Rotter, Paola Sebastiani, Jennifer Smith, Thorkild I. A. Sørensen, Kent D. Taylor, André G. Uitterlinden, Wiesje van der Flier, Sven J. van der Lee, Cornelia M. van Duijn, Diana van Heemst, James W. Vaupel, David Weir, Kenny Ye, Yi Zeng, Wanlin Zheng, Henne Holstege, Douglas P. Kiel, Kathryn L. Lunetta, P. Eline Slagboom, Joanne M. Murabito

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