A Multi-Compartment Model of Glioma Response to Fractionated Radiation Therapy Parameterized via Time-Resolved Microscopy Data by Junyan Liu, David A. Hormuth, David A. Hormuth, Jianchen Yang, Thomas E. Yankeelov, Thomas E. Yankeelov, Thomas E. Yankeelov, Thomas E. Yankeelov, Thomas E. Yankeelov, Thomas E. Yankeelov

Get full text

Mathematical characterization of population dynamics in breast cancer cells treated with doxorubicin by Emily Y. Yang, Grant R. Howard, Amy Brock, Amy Brock, Amy Brock, Thomas E. Yankeelov, Thomas E. Yankeelov, Thomas E. Yankeelov, Thomas E. Yankeelov, Thomas E. Yankeelov, Thomas E. Yankeelov, Guillermo Lorenzo, Guillermo Lorenzo

Get full text

Leveraging Mathematical Modeling to Quantify Pharmacokinetic and Pharmacodynamic Pathways: Equivalent Dose Metric by Matthew T. McKenna, Matthew T. McKenna, Jared A. Weis, Jared A. Weis, Vito Quaranta, Thomas E. Yankeelov, Thomas E. Yankeelov, Thomas E. Yankeelov, Thomas E. Yankeelov, Thomas E. Yankeelov

Get full text

Predictive digital twin for optimizing patient-specific radiotherapy regimens under uncertainty in high-grade gliomas by Anirban Chaudhuri, Graham Pash, David A. Hormuth, David A. Hormuth, Guillermo Lorenzo, Guillermo Lorenzo, Michael Kapteyn, Chengyue Wu, Ernesto A. B. F. Lima, Ernesto A. B. F. Lima, Thomas E. Yankeelov, Thomas E. Yankeelov, Thomas E. Yankeelov, Thomas E. Yankeelov, Thomas E. Yankeelov, Thomas E. Yankeelov, Karen Willcox

Get full text

Tumor Microenvironment Alters Chemoresistance of Hepatocellular Carcinoma Through CYP3A4 Metabolic Activity by Alican Özkan, Danielle L. Stolley, Erik N. K. Cressman, Matthew McMillin, Matthew McMillin, Sharon DeMorrow, Sharon DeMorrow, Sharon DeMorrow, Thomas E. Yankeelov, Thomas E. Yankeelov, Thomas E. Yankeelov, Thomas E. Yankeelov, Thomas E. Yankeelov, Marissa Nichole Rylander, Marissa Nichole Rylander, Marissa Nichole Rylander

Get full text

Implementing multiphysics models in FEniCS: Viscoelastic flows, poroelasticity, and tumor growth by Birkan Tunç, Gregory J. Rodin, Thomas E. Yankeelov

Get full text

Forecasting tumor and vasculature response dynamics to radiation therapy via image based mathematical modeling by David A. Hormuth, Angela M. Jarrett, Thomas E. Yankeelov

Get full text

Modeling the effect of intra-voxel diffusion of contrast agent on the quantitative analysis of dynamic contrast enhanced magnetic resonance imaging. by Stephanie L Barnes, C Chad Quarles, Thomas E Yankeelov

Get full text

Quantification of long-term doxorubicin response dynamics in breast cancer cell lines to direct treatment schedules. by Grant R Howard, Tyler A Jost, Thomas E Yankeelov, Amy Brock

Get full text

Towards an Image-Informed Mathematical Model of In Vivo Response to Fractionated Radiation Therapy by David A. Hormuth, Angela M. Jarrett, Tessa Davis, Thomas E. Yankeelov

Get full text

A data assimilation framework to predict the response of glioma cells to radiation by Junyan Liu, David A. Hormuth II, Jianchen Yang, Thomas E. Yankeelov

Get full text

Practical Dynamic Contrast Enhanced MRI in Small Animal Models of Cancer: Data Acquisition, Data Analysis, and Interpretation by Jennifer G. Whisenant, Mary E. Loveless, Thomas E. Yankeelov, Stephanie L. Barnes

Get full text

Toward mechanistic medical digital twins: some use cases in immunology by Reinhard Laubenbacher, Fred Adler, Gary An, Filippo Castiglione, Stephen Eubank, Luis L. Fonseca, James Glazier, Tomas Helikar, Marti Jett-Tilton, Denise Kirschner, Paul Macklin, Borna Mehrad, Beth Moore, Virginia Pasour, Ilya Shmulevich, Amber Smith, Isabel Voigt, Thomas E. Yankeelov, Thomas E. Yankeelov, Thomas E. Yankeelov, Tjalf Ziemssen

Get full text

DCEMRI.jl: a fast, validated, open source toolkit for dynamic contrast enhanced MRI analysis by David S. Smith, Xia Li, Lori R. Arlinghaus, Thomas E. Yankeelov, E. Brian Welch

Get full text

Precision Medicine with Imprecise Therapy: Computational Modeling for Chemotherapy in Breast Cancer by Matthew T. McKenna, Jared A. Weis, Amy Brock, Vito Quaranta, Thomas E. Yankeelov

Get full text

Characterizing Trastuzumab-Induced Alterations in Intratumoral Heterogeneity with Quantitative Imaging and Immunohistochemistry in HER2+ Breast Cancer by Anum K. Syed, Ryan Woodall, Jennifer G. Whisenant, Thomas E. Yankeelov, Anna G. Sorace

Get full text

Quantifying the Effects of Combination Trastuzumab and Radiation Therapy in Human Epidermal Growth Factor Receptor 2-Positive Breast Cancer by Meghan J. Bloom, Patrick N. Song, John Virostko, Thomas E. Yankeelov, Anna G. Sorace

Get full text

Image-based personalization of computational models for predicting response of high-grade glioma to chemoradiation by David A. Hormuth, Karine A. Al Feghali, Andrew M. Elliott, Thomas E. Yankeelov, Caroline Chung

Get full text

Comparing mechanism-based and machine learning models for predicting the effects of glucose accessibility on tumor cell proliferation by Jianchen Yang, Jack Virostko, Junyan Liu, Angela M. Jarrett, David A. Hormuth, Thomas E. Yankeelov

Get full text

Multiparametric Analysis of Longitudinal Quantitative MRI Data to Identify Distinct Tumor Habitats in Preclinical Models of Breast Cancer by Anum K. Syed, Jennifer G. Whisenant, Stephanie L. Barnes, Anna G. Sorace, Thomas E. Yankeelov

Get full text