Expression of HLA class II molecules in humanized NOD.Rag1KO.IL2RgcKO mice is critical for development and function of human T and B cells. by Rebecca Danner, Snehal N Chaudhari, John Rosenberger, Jacqueline Surls, Thomas L Richie, Teodor-Doru Brumeanu, Sofia Casares

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Correction: Modification of Ad5 Hexon Hypervariable Regions Circumvents Pre-Existing Ad5 Neutralizing Antibodies and Induces Protective Immune Responses. by Joseph T. Bruder, Elena Semenova, Ping Chen, Keith Limbach, Noelle B. Patterson, Maureen E. Stefaniak, Svetlana Konovalova, Charlie Thomas, Melissa Hamilton, C. Richter King, Thomas L. Richie, Denise L. Doolan

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Modification of Ad5 hexon hypervariable regions circumvents pre-existing Ad5 neutralizing antibodies and induces protective immune responses. by Joseph T Bruder, Elena Semenova, Ping Chen, Keith Limbach, Noelle B Patterson, Maureen E Stefaniak, Svetlana Konovalova, Charlie Thomas, Melissa Hamilton, C Richter King, Thomas L Richie, Denise L Doolan

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Two cases of long-lasting, sub-microscopic Plasmodium malariae infections in adults from coastal Tanzania by Tobias Schindler, Said Jongo, Fabian Studer, Maximilian Mpina, Grace Mwangoka, Sarah Mswata, Kamaka Ramadhani, Julian Sax, L. W. Preston Church, Thomas L. Richie, Marcel Tanner, Stephen L. Hoffman, Salim Abdulla, Claudia Daubenberger

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Expansion of Functional Myeloid-Derived Suppressor Cells in Controlled Human Malaria Infection by Carlos Lamsfus Calle, Rolf Fendel, Rolf Fendel, Rolf Fendel, Anurag Singh, Anurag Singh, Thomas L. Richie, Stephen L. Hoffman, Peter G. Kremsner, Peter G. Kremsner, Peter G. Kremsner, Benjamin Mordmüller, Benjamin Mordmüller, Benjamin Mordmüller

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A First for Human Vaccinology: GMP Compliant Radiation Attenuation of Plasmodium falciparum Sporozoites for Production of a Vaccine Against Malaria by Eric R. James, Steve Matheny, James Overby, B. Kim Lee Sim, Abraham G. Eappen, Tao Li, Ming Lin Li, Thomas L. Richie, Sumana Chakravarty, Anusha Gunasekera, Tooba Murshedkar, Peter F. Billingsley, Stephen L. Hoffman

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Protective Efficacy of Plasmodium vivax Radiation-Attenuated Sporozoites in Colombian Volunteers: A Randomized Controlled Trial. by Myriam Arévalo-Herrera, Juan M Vásquez-Jiménez, Mary Lopez-Perez, Andrés F Vallejo, Andrés B Amado-Garavito, Nora Céspedes, Angélica Castellanos, Karen Molina, Johanna Trejos, José Oñate, Judith E Epstein, Thomas L Richie, Sócrates Herrera

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Profiling the Targets of Protective CD8+ T Cell Responses to Infection by Joseph T. Bruder, Ping Chen, Greg Ekberg, Emily C. Smith, Christopher A. Lazarski, Bennett A. Myers, Jessica Bolton, Martha Sedegah, Eileen Villasante, Thomas L. Richie, C. Richter King, Joao C. Aguiar, Denise L. Doolan, Douglas E. Brough

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PfSPZ-CVac efficacy against malaria increases from 0% to 75% when administered in the absence of erythrocyte stage parasitemia: A randomized, placebo-controlled trial with controll... by Sean C Murphy, Gregory A Deye, B Kim Lee Sim, Shirley Galbiati, Jessie K Kennedy, Kristen W Cohen, Sumana Chakravarty, Natasha Kc, Yonas Abebe, Eric R James, James G Kublin, Stephen L Hoffman, Thomas L Richie, Lisa A Jackson

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Plasmodium falciparum 7G8 challenge provides conservative prediction of efficacy of PfNF54-based PfSPZ Vaccine in Africa by Joana C. Silva, Ankit Dwivedi, Kara A. Moser, Mahamadou S. Sissoko, Judith E. Epstein, Sara A. Healy, Kirsten E. Lyke, Benjamin Mordmüller, Peter G. Kremsner, Patrick E. Duffy, Tooba Murshedkar, B. Kim Lee Sim, Thomas L. Richie, Stephen L. Hoffman

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IMRAS-Immunization with radiation-attenuated Plasmodium falciparum sporozoites by mosquito bite: Cellular immunity to sporozoites, CSP, AMA1, TRAP and CelTOS. by Martha Sedegah, Michael R Hollingdale, Harini Ganeshan, Maria Belmonte, Jun Huang, Arnel Belmonte, Sandra Inoue, Rachel Velasco, Bradley Hickey, Nimfa Teneza-Mora, Joanne Lumsden, Sharina Reyes, Jo Glenna Banania, Anatalio Reyes, Ivelese Guzman, Thomas L Richie, Judith E Epstein, Eileen Villasante

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Sterile immunity to malaria after DNA prime/adenovirus boost immunization is associated with effector memory CD8+T cells targeting AMA1 class I epitopes. by Martha Sedegah, Michael R Hollingdale, Fouzia Farooq, Harini Ganeshan, Maria Belmonte, Yohan Kim, Bjoern Peters, Alessandro Sette, Jun Huang, Shannon McGrath, Esteban Abot, Keith Limbach, Meng Shi, Lorraine Soisson, Carter Diggs, Ilin Chuang, Cindy Tamminga, Judith E Epstein, Eileen Villasante, Thomas L Richie

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A glycolipid adjuvant, 7DW8-5, enhances CD8+ T cell responses induced by an adenovirus-vectored malaria vaccine in non-human primates. by Neal N Padte, Mar Boente-Carrera, Chasity D Andrews, Jenny McManus, Brooke F Grasperge, Agegnehu Gettie, Jordana G Coelho-dos-Reis, Xiangming Li, Douglass Wu, Joseph T Bruder, Martha Sedegah, Noelle Patterson, Thomas L Richie, Chi-Huey Wong, David D Ho, Sandhya Vasan, Moriya Tsuji

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Discovery of Novel Plasmodium falciparum Pre-Erythrocytic Antigens for Vaccine Development. by Joao C Aguiar, Jessica Bolton, Joyce Wanga, John B Sacci, Hideyuki Iriko, Julie K Mazeika, Eun-Taek Han, Keith Limbach, Noelle B Patterson, Martha Sedegah, Ann-Marie Cruz, Takafumi Tsuboi, Stephen L Hoffman, Daniel Carucci, Michael R Hollingdale, Eileen D Villasante, Thomas L Richie

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Sterile protection against Plasmodium knowlesi in rhesus monkeys from a malaria vaccine: comparison of heterologous prime boost strategies. by George Jiang, Meng Shi, Solomon Conteh, Nancy Richie, Glenna Banania, Harini Geneshan, Anais Valencia, Priti Singh, Joao Aguiar, Keith Limbach, Kurt I Kamrud, Jonathan Rayner, Jonathan Smith, Joseph T Bruder, C Richter King, Takafumi Tsuboi, Satoru Takeo, Yaeta Endo, Denise L Doolan, Thomas L Richie, Walter R Weiss

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New gorilla adenovirus vaccine vectors induce potent immune responses and protection in a mouse malaria model by Keith Limbach, Maureen Stefaniak, Ping Chen, Noelle B. Patterson, Grant Liao, Shaojie Weng, Svetlana Krepkiy, Greg Ekberg, Holly Torano, Damodar Ettyreddy, Kalpana Gowda, Sharvari Sonawane, Arnel Belmonte, Esteban Abot, Martha Sedegah, Michael R. Hollingdale, Ann Moormann, John Vulule, Eileen Villasante, Thomas L. Richie, Douglas E. Brough, Joseph T. Bruder

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Novel malaria antigen Plasmodium yoelii E140 induces antibody-mediated sterile protection in mice against malaria challenge. by Emily C Smith, Keith J Limbach, Nonenipha Rangel, Kyosuke Oda, Jessica S Bolton, Mengyan Du, Kalpana Gowda, Jianyang Wang, J Kathleen Moch, Sharvari Sonawane, Rachel Velasco, Arnel Belmonte, Rebecca Danner, Joanne M Lumsden, Noelle B Patterson, Martha Sedegah, Michael R Hollingdale, Thomas L Richie, John B Sacci, Eileen D Villasante, Joao C Aguiar

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PfSPZ-CVac malaria vaccine demonstrates safety among malaria-experienced adults: A randomized, controlled phase 1 trial by Drissa Coulibaly, Abdoulaye K. Kone, Karim Traore, Amadou Niangaly, Bourema Kouriba, Charles Arama, Amatigue Zeguime, Amagana Dolo, Kirsten E. Lyke, Christopher V. Plowe, Yonas Abebe, Gail E. Potter, Jessie K. Kennedy, Shirley M. Galbiati, Effie Nomicos, Gregory A. Deye, Thomas L. Richie, Eric R. James, Natasha KC, B. Kim Lee Sim, Stephen L. Hoffman, Ogobara K. Doumbo, Mahamadou A. Thera, Matthew B. Laurens

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A PfSPZ vaccine immunization regimen equally protective against homologous and heterologous controlled human malaria infection by Benjamin Mordmüller, Zita Sulyok, Mihály Sulyok, Zsofia Molnar, Albert Lalremruata, Carlos Lamsfus Calle, Patricia Granados Bayon, Meral Esen, Markus Gmeiner, Jana Held, Henri-Lynn Heimann, Tamirat Gebru Woldearegai, Javier Ibáñez, Judith Flügge, Rolf Fendel, Andrea Kreidenweiss, Natasha KC, Tooba Murshedkar, Sumana Chakravarty, Pouria Riyahi, Peter F. Billingsley, L. W. Preston Church, Thomas L. Richie, B. Kim Lee Sim, Stephen L. Hoffman, Peter G. Kremsner

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Phase 1/2a Trial of Plasmodium vivax Malaria Vaccine Candidate VMP001/AS01B in Malaria-Naive Adults: Safety, Immunogenicity, and Efficacy. by Jason W Bennett, Anjali Yadava, Donna Tosh, Jetsumon Sattabongkot, Jack Komisar, Lisa A Ware, William F McCarthy, Jessica J Cowden, Jason Regules, Michele D Spring, Kristopher Paolino, Joshua D Hartzell, James F Cummings, Thomas L Richie, Joanne Lumsden, Edwin Kamau, Jittawadee Murphy, Cynthia Lee, Falgunee Parekh, Ashley Birkett, Joe Cohen, W Ripley Ballou, Mark E Polhemus, Yannick F Vanloubbeeck, Johan Vekemans, Christian F Ockenhouse

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