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Challenges in Optimising the Successful Construction of Antibody Drug Conjugates in Cancer Therapy by Thomas Mehrling, Daniel Soltis
Published 2018-02-01
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The first-in-class alkylating deacetylase inhibitor molecule tinostamustine shows antitumor effects and is synergistic with radiotherapy in preclinical models of glioblastoma by Claudio Festuccia, Andrea Mancini, Alessandro Colapietro, Giovanni Luca Gravina, Flora Vitale, Francesco Marampon, Simona Delle Monache, Simona Pompili, Loredana Cristiano, Antonella Vetuschi, Vincenzo Tombolini, Yi Chen, Thomas Mehrling
Published 2018-02-01
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Preclinical anti-myeloma activity of EDO-S101, a new bendamustine-derived molecule with added HDACi activity, through potent DNA damage induction and impairment of DNA repair by Ana-Alicia López-Iglesias, Ana B. Herrero, Marta Chesi, Laura San-Segundo, Lorena González-Méndez, Susana Hernández-García, Irena Misiewicz-Krzeminska, Dalia Quwaider, Montserrat Martín-Sánchez, Daniel Primo, Teresa Paíno, P. Leif Bergsagel, Thomas Mehrling, Marcos González-Díaz, Jesús F. San-Miguel, María-Victoria Mateos, Norma C. Gutiérrez, Mercedes Garayoa, Enrique M. Ocio
Published 2017-06-01
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Establishment and Characterization of a Reliable Xenograft Model of Hodgkin Lymphoma Suitable for the Study of Tumor Origin and the Design of New Therapies by Radhia M’kacher, Monika Frenzel, Mustafa Al Jawhari, Steffen Junker, Corina Cuceu, Luc Morat, Anne-Laure Bauchet, Lev Stimmer, Aude Lenain, Nathalie Dechamps, William M. Hempel, Geraldine Pottier, Leonhard Heidingsfelder, Eric Laplagne, Claire Borie, Noufissa Oudrhiri, Dima Jouni, Annelise Bennaceur-Griscelli, Bruno Colicchio, Alain Dieterlen, Theodore Girinsky, Raphael Boisgard, Jean Bourhis, Jacques Bosq, Thomas Mehrling, Eric Jeandidier, Patrice Carde
Published 2018-10-01
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Purine nucleoside phosphorylase enables dual metabolic checkpoints that prevent T cell immunodeficiency and TLR7-associated autoimmunity by Evan R. Abt, Khalid Rashid, Thuc M. Le, Suwen Li, Hailey R. Lee, Vincent Lok, Luyi Li, Amanda L. Creech, Amanda N. Labora, Hanna K. Mandl, Alex K. Lam, Arthur Cho, Valerie Rezek, Nanping Wu, Gabriel Abril-Rodriguez, Ethan W. Rosser, Steven D. Mittelman, Willy Hugo, Thomas Mehrling, Shanta Bantia, Antoni Ribas, Timothy R. Donahue, Gay M. Crooks, Ting-Ting Wu, Caius G. Radu
Published 2022-08-01
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