Treatment with JQ1, a BET bromodomain inhibitor, is selectively detrimental to R6/2 Huntington’s disease mice by Kedaigle, Amanda J, Reidling, Jack C, Lim, Ryan G, Adam, Miriam, Wu, Jie, Wassie, Brook T., Stocksdale, Jennifer T, Casale, Malcolm S, Fraenkel, Ernest, Thompson, Leslie M

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Exogenous delivery of chaperonin subunit fragment ApiCCT1 modulates mutant Huntingtin cellular phenotypes by Sontag, Emily M., Joachimiak, Lukasz A., Tan, Zhiqun, Tomlinson, Anthony, Glabe, Charles G., Potkin, Steven G., Frydman, Judith, Thompson, Leslie M., Housman, David E

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IKKβ slows Huntington’s disease progression in R6/1 mice by Ochaba, Joseph, Fote, Gianna, Kachemov, Marketta, Thein, Soe, Yeung, Sylvia Y., Lau, Alice L., Hernandez, Sarah, Lim, Ryan G., Casale, Malcolm, Neel, Michael J., Monuki, Edwin S., Reidling, Jack, Housman, David E, Thompson, Leslie M., Steffan, Joan S.

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Huntington’s Disease iPSC-Derived Brain Microvascular Endothelial Cells Reveal WNT-Mediated Angiogenic and Blood-Brain Barrier Deficits by Lim, Ryan G., Quan, Chris, Reyes-Ortiz, Andrea M., Lutz, Sarah E., Kedaigle, Amanda J., Wu, Jie, Vatine, Gad D., Stocksdale, Jennifer, Casale, Malcolm S., Svendsen, Clive N., Fraenkel, Ernest, Agalliu, Dritan, Thompson, Leslie M., Wasylenko, Theresa Anne, Housman, David E

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Aberrant Development Corrected in Adult-Onset Huntington's Disease iPSC-Derived Neuronal Cultures via WNT Signaling Modulation by Smith-Geater, Charlene, Hernandez, Sarah J, Lim, Ryan G, Adam, Miriam, Wu, Jie, Stocksdale, Jennifer T, Wassie, Brook T, Gold, Maxwell Philip, Wang, Keona Q, Miramontes, Ricardo, Kopan, Lexi, Orellana, Iliana, Joy, Shona, Kemp, Paul J, Allen, Nicholas D, Fraenkel, Ernest, Thompson, Leslie M

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Aberrant Development Corrected in Adult-Onset Huntington's Disease iPSC-Derived Neuronal Cultures via WNT Signaling Modulation by Smith-Geater, Charlene, Hernandez, Sarah J, Lim, Ryan G, Adam, Miriam, Wu, Jie, Stocksdale, Jennifer T, Wassie, Brook T, Gold, Maxwell Philip, Wang, Keona Q, Miramontes, Ricardo, Kopan, Lexi, Orellana, Iliana, Joy, Shona, Kemp, Paul J, Allen, Nicholas D, Fraenkel, Ernest, Thompson, Leslie M

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Potential function for the Huntingtin protein as a scaffold for selective autophagy by Ochaba, Joseph, Csikos, George, Zheng, Shuqiu, Margulis, Julia, Salazar, Lisa, Mao, Kai, Lau, Alice L., Yeung, Sylvia Y., Humbert, Sandrine, Klionsky, Daniel J., Finkbeiner, Steven, Zeitlin, Scott O., Marsh, J. Lawrence, Thompson, Leslie M., Steffan, Joan S., Lukacsovich, Tamas, Saudou, Frederic, Housman, David E

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Targeting H3K4 trimethylation in Huntington disease by Ng, Christopher W., Yildirim, Ferah, Labadorf, Adam, Fraenkel, Ernest, Vashishtha, Malini, Kratter, Ian H., Bodai, Laszlo, Song, Wan, Lau, Alice L., Vogel-Ciernia, Annie, Troncosco, Juan, Ross, Christopher A., Bates, Gillian P., Krainc, Dimitri, Sadri-Vakili, Ghazaleh, Finkbeiner, Steven, Marsh, J. Lawrence, Thompson, Leslie M., Wasylenko, Theresa Anne, Housman, David E

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Huntington disease oligodendrocyte maturation deficits revealed by single-nucleus RNAseq are rescued by thiamine-biotin supplementation by Lim, Ryan G, Al-Dalahmah, Osama, Wu, Jie, Gold, Maxwell P, Reidling, Jack C, Tang, Guomei, Adam, Miriam, Dansu, David K, Park, Hye-Jin, Casaccia, Patrizia, Miramontes, Ricardo, Reyes-Ortiz, Andrea M, Lau, Alice, Hickman, Richard A, Khan, Fatima, Paryani, Fahad, Tang, Alice, Ofori, Kenneth, Miyoshi, Emily, Michael, Neethu, McClure, Nicolette, Flowers, Xena E, Vonsattel, Jean Paul, Davidson, Shawn, Menon, Vilas, Swarup, Vivek, Fraenkel, Ernest, Goldman, James E, Thompson, Leslie M

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Developmental alterations in Huntington's disease neural cells and pharmacological rescue in cells and mice by HD iPSC Consortium, Lim, Ryan G, Salazar, Lisa L, Wilton, Daniel K, King, Alvin R, Stocksdale, Jennifer T, Sharifabad, Delaram, Lau, L Alice, Stevens, Beth, Reidling, Jack C, Winokur, Sara T, Casale, Malcolm S, Thompson, Leslie M, Pardo, Mónica, Díaz-Barriga, A Gerardo García, Straccia, Marco, Sanders, Phil, Alberch, Jordi, Canals, Josep M, Kaye, Julia A, Dunlap, Mariah, Jo, Lisa, May, Hanna, Mount, Elliot, Anderson-Bergman, Cliff, Haston, Kelly, Finkbeiner, Steven, Allen, Nicholas D, Kemp, Paul J, Atwal, Ranjit Singh, Biagioli, Marta, Gusella, James F, MacDonald, Marcy E, Akimov, Sergey S, Arbez, Nicolas, Stewart, Jacqueline, Ross, Christopher A, Mattis, Virginia B, Tom, Colton M, Mattis, Virginia B, Tom, Colton M, Ornelas, Loren, Sahabian, Anais, Lenaeus, Lindsay, Mandefro, Berhan, Sareen, Dhruv, Svendsen, Clive N, Kedaigle, Amanda Joy, Wasylenko, Theresa Anne, Yildirim, Ferah, Ng, Christopher W., Milani, Pamela, Housman, David E, Fraenkel, Ernest

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