Long non-coding RNA tagging and expression manipulation via CRISPR/Cas9-mediated targeted insertion di Tian-Lin Cheng, Zilong Qiu

Testo

Expanding C–T base editing toolkit with diversified cytidine deaminases di Tian-Lin Cheng, Shuo Li, Bo Yuan, Xiaolin Wang, Wenhao Zhou, Zilong Qiu

Testo

Identification of autism-related MECP2 mutations by whole-exome sequencing and functional validation di Zhu Wen, Tian-Lin Cheng, Gai-zhi Li, Shi-Bang Sun, Shun-Ying Yu, Yi Zhang, Ya-Song Du, Zilong Qiu

Testo

Neuromuscular organoids model spinal neuromuscular pathologies in C9orf72 amyotrophic lateral sclerosis di Chong Gao, Qinghua Shi, Xue Pan, Jiajia Chen, Yuhong Zhang, Jiali Lang, Shan Wen, Xiaodong Liu, Tian-Lin Cheng, Kai Lei

Testo

TadA orthologs enable both cytosine and adenine editing of base editors di Shuqian Zhang, Bo Yuan, Jixin Cao, Liting Song, Jinlong Chen, Jiayi Qiu, Zilong Qiu, Xing-Ming Zhao, Jingqi Chen, Tian-Lin Cheng

Testo

Docking sites inside Cas9 for adenine base editing diversification and RNA off-target elimination di Shuo Li, Bo Yuan, Jixin Cao, Jingqi Chen, Jinlong Chen, Jiayi Qiu, Xing-Ming Zhao, Xiaolin Wang, Zilong Qiu, Tian-Lin Cheng

Testo

TadA reprogramming to generate potent miniature base editors with high precision di Shuqian Zhang, Liting Song, Bo Yuan, Cheng Zhang, Jixin Cao, Jinlong Chen, Jiayi Qiu, Yilin Tai, Jingqi Chen, Zilong Qiu, Xing-Ming Zhao, Tian-Lin Cheng

Testo