464 Clonal replacement of tumor-infiltrating CD8+ T cells by induction and activation of tumor-residing Batf3-dependent dendritic cells by Tibor Keler, Song Liu, Mark Long, Henry Marsh, Takaaki Oba, Fumito Ito, Hans Minderman, Scott Abrams

Overcoming primary and acquired resistance to anti-PD-L1 therapy by induction and activation of tumor-residing cDC1s by Takaaki Oba, Mark D. Long, Tibor Keler, Henry C. Marsh, Hans Minderman, Scott I. Abrams, Song Liu, Fumito Ito

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The CD27/CD70 pathway negatively regulates visceral adipose tissue-resident Th2 cells and controls metabolic homeostasis by Kevin Englebert, Anaelle Taquin, Abdulkader Azouz, Valérie Acolty, Sylvie Vande Velde, Marie Vanhollebeke, Hadrien Innes, Louis Boon, Tibor Keler, Oberdan Leo, Stanislas Goriely, Muriel Moser, Guillaume Oldenhove

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M. tuberculosis-Initiated Human Mannose Receptor Signaling Regulates Macrophage Recognition and Vesicle Trafficking by FcRγ-Chain, Grb2, and SHP-1 by Murugesan V.S. Rajaram, Eusondia Arnett, Abul K. Azad, Evelyn Guirado, Bin Ni, Abigail D. Gerberick, Li-Zhen He, Tibor Keler, Lawrence J. Thomas, William P. Lafuse, Larry S. Schlesinger

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Flt3L-Mediated Expansion of Plasmacytoid Dendritic Cells Suppresses HIV Infection in Humanized Mice by Tram N.Q. Pham, Oussama Meziane, Mohammad Alam Miah, Olga Volodina, Chloé Colas, Kathie Béland, Yuanyi Li, Frédéric Dallaire, Tibor Keler, Jean V. Guimond, Sylvie Lesage, Cheolho Cheong, Élie Haddad, Éric A. Cohen

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CD27 stimulation unveils the efficacy of linked class I/II peptide vaccines in poorly immunogenic tumors by orchestrating a coordinated CD4/CD8 T cell response by Katherine A. Riccione, Li-Zhen He, Peter E. Fecci, Pamela K. Norberg, Carter M. Suryadevara, Adam Swartz, Patrick Healy, Elizabeth Reap, Tibor Keler, Qi-Jing Li, Kendra L. Congdon, Luis Sanchez-Perez, John H. Sampson

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Agonistic CD27 antibody potency is determined by epitope-dependent receptor clustering augmented through Fc-engineering by Franziska Heckel, Anna H. Turaj, Hayden Fisher, H. T. Claude Chan, Michael J. E. Marshall, Osman Dadas, Christine A. Penfold, Tatyana Inzhelevskaya, C. Ian Mockridge, Diego Alvarado, Ivo Tews, Tibor Keler, Stephen A. Beers, Mark S. Cragg, Sean H. Lim

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Tissue-specific modifier alleles determine Mertk loss-of-function traits by Yemsratch T Akalu, Maria E Mercau, Marleen Ansems, Lindsey D Hughes, James Nevin, Emily J Alberto, Xinran N Liu, Li-Zhen He, Diego Alvarado, Tibor Keler, Yong Kong, William M Philbrick, Marcus Bosenberg, Silvia C Finnemann, Antonio Iavarone, Anna Lasorella, Carla V Rothlin, Sourav Ghosh

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1522 Revitalizing systemic immune responses in progressive NSCLC using FLT3L and SBRT by Tibor Keler, Balazs Halmos, Divij Mathew, Chandan Guha, Jeffrey M Levsky, E John Wherry, Josephine R Giles, Nitin Ohri, Shin Foong Ngiow, KC Wumesh, Madhur Garg, Haiying Cheng, Rasim Gucalp, William Bodner, Rafi Kabarriti, Claudia Gutierrez-Chavez, Adel Zakharia, Shalom Kalnicki, Michael J Yellin

CDX-585, a Bispecific Antibody with Dual Targeting of ILT4 and PD-1 Checkpoint Pathways by Michael B. Murphy, Laura Vitale, Shukai Xia, Zeyu Peng, Thomas O’Neill, Jay Lillquist, Anna Wasiuk, Jeff Weidlick, Jenifer Widger, Laura Mills-Chen, Andrea Crocker, Colleen Patterson, James Boyer, April R. Baronas, Mingjiu Chen, Hugh M. Davis, Mark Ma, Joel Goldstein, Lawrence J. Thomas, Diego Alvarado, Henry C. Marsh, Tibor Keler

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Safety, tolerability and efficacy of agonist anti-CD27 antibody (varlilumab) administered in combination with anti-PD-1 (nivolumab) in advanced solid tumors by Mario Sznol, Michael Yellin, Tibor Keler, Jose Lutzky, Amy Weise, Margaret K Callahan, Osama Rahma, Rachel E Sanborn, Alexander Starodub, Deepa S Subramaniam, Antonio Jimeno, Tracey Rawls, David A Reardon, Daniel C Cho, Rhonda L Bitting, Michael J Pishvaian, Branimir I Sikic, Naiyer A Rizvi, Julie E Bauman, Thomas Kaley, Fabio Iwamoto, Joachim M Baehring, Jeanny B Aragon-Ching, Thomas R Hawthorne

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