Underrepresentation of Hispanics in clinical trials for liver cancer in the United States over the past 20 years by Cecilia Monge, Tim F. Greten

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Current frontline approaches in the management of hepatocellular carcinoma: the evolving role of immunotherapy by Gagandeep Brar, Tim F. Greten, Zachary J. Brown

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Evaluating the impact of hydroxychloroquine on mouse lymphocyte proliferation and cytokine production in vivo and in vitro by Simon Wabitsch, Justin D. McCallen, Chi Ma, Tim F. Greten

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Checkpoint Inhibitors Modulate Plasticity of Innate Lymphoid Cells in Peripheral Blood of Patients With Hepatocellular Carcinoma by Bernd Heinrich, Bernd Heinrich, Benjamin Ruf, Varun Subramanyam, Yuta Myojin, Chunwei W. Lai, Chunwei W. Lai, Amanda J. Craig, Jianyang Fu, Changqing Xie, Alexander Kroemer, Tim F. Greten, Tim F. Greten, Firouzeh Korangy

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Tumor induced hepatic myeloid derived suppressor cells can cause moderate liver damage. by Tobias Eggert, José Medina-Echeverz, Tamar Kapanadze, Michael J Kruhlak, Firouzeh Korangy, Tim F Greten

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miR-130a and miR-145 reprogram Gr-1+CD11b+ myeloid cells and inhibit tumor metastasis through improved host immunity by Hiroki Ishii, Suman K. Vodnala, Bhagelu R. Achyut, Jae Young So, M. Christine Hollander, Tim F. Greten, Ashish Lal, Li Yang

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Hepatocellular Carcinoma Survival by Etiology: A SEER‐Medicare Database Analysis by Gagandeep Brar, Tim F. Greten, Barry I. Graubard, Timothy S. McNeel, Jessica L. Petrick, Katherine A. McGlynn, Sean F. Altekruse

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Hydroxychloroquine can impair tumor response to anti-PD1 in subcutaneous mouse models by Simon Wabitsch, John C. McVey, Chi Ma, Benjamin Ruf, Olena Kamenyeva, Justin D. McCallen, Laurence P. Diggs, Bernd Heinrich, Tim F. Greten

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585 Ofranergene obadenovec (VB-111) in combination with nivolumab in patients with microsatellite stable colorectal liver metastases: a single-center, single-arm phase II trial by David E Kleiner, Tim F Greten, Cecilia Monge, Seth M Steinberg, Changqing Xie, Yuta Myojin, Kelley Coffman, Bradford J Wood, Bernadette Redd, Donna M Hrones, Elliott B Levy

472 Anti-VEGF treatment amplifies immune checkpoint inhibitor induced immune responses by targeting B and regulatory T cells by Patrick Huang, Chi Ma, Tim F Greten, Firouzeh Korangy, Benjamin Ruf, William Telford, Mohamed-Reda Benmebarek, Cihan Oguz, Yuta Myojin, Matthias Seifert, Justin Lack, Kylynda Bauer, Marina Villamor Paya

Anti–PD-1 in Combination With Trametinib Suppresses Tumor Growth and Improves Survival of Intrahepatic Cholangiocarcinoma in MiceSummary by Simon Wabitsch, Mayank Tandon, Benjamin Ruf, Qianfei Zhang, Justin D. McCallen, John C. McVey, Chi Ma, Benjamin L. Green, Laurence P. Diggs, Bernd Heinrich, Tim F. Greten

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VB-111 (ofranergene obadenovec) in combination with nivolumab in patients with microsatellite stable colorectal liver metastases: a single center, single arm, phase II trial by Tim F Greten, Cecilia Monge, Seth M Steinberg, William Douglas Figg, David Kleiner, Changqing Xie, Yuta Myojin, Donna Mabry Hrones, Bradford J Wood, Elliot B Levy, Bernadette Redd, Kelley Coffman-D'Annibale

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Adenosine A2a receptor inhibition increases the anti-tumor efficacy of anti-PD1 treatment in murine hepatobiliary cancers by Yuta Myojin, Justin D. McCallen, Chi Ma, Kylynda C. Bauer, Benjamin Ruf, Mohamed-Reda Benmebarek, Benjamin L. Green, Simon Wabitsch, John C. McVey, Claude Fu, Changqing Xie, Tim F. Greten

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988 Vagal-CD8+ T cell neuroimmune axis modulates liver cancer by Chi Ma, Tim F Greten, Firouzeh Korangy, Benjamin L Green, Benjamin Ruf, Mohamed-Reda Benmebarek, Yuta Myojin, Jonathan Qi, Simon Wabitsch, Amran Nur, Kylynda C Bauer, Rajiv Trehan, Danielle Springer, Audrey Noguchi, Morteza Peiravi, Heather Potts

A phase 2 trial of gemcitabine and docetaxel in patients with metastatic colorectal adenocarcinoma with methylated checkpoint with forkhead and ring finger domain promoter and/or m... by Marina Baretti, Enusha Karunasena, Marianna Zahurak, Rosalind Walker, Yang Zhao, Thomas R. Pisanic 2nd, Tza‐Huei Wang, Tim F. Greten, Austin G. Duffy, Elske Gootjes, Gerrit Meijer, Henk M.W. Verheul, Nita Ahuja, James G. Herman, Nilofer S. Azad

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Multiregional single-cell dissection of tumor and immune cells reveals stable lock-and-key features in liver cancer by Lichun Ma, Sophia Heinrich, Limin Wang, Friederike L. Keggenhoff, Subreen Khatib, Marshonna Forgues, Michael Kelly, Stephen M. Hewitt, Areeba Saif, Jonathan M. Hernandez, Donna Mabry, Roman Kloeckner, Tim F. Greten, Jittiporn Chaisaingmongkol, Mathuros Ruchirawat, Jens U. Marquardt, Xin Wei Wang

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Combined immune checkpoint inhibition with durvalumab and tremelimumab with and without radiofrequency ablation in patients with advanced biliary tract carcinoma by Cecilia Monge, Changqing Xie, Yuta Myojin, Kelley L. Coffman‐D'Annibale, Donna Hrones, Gagandeep Brar, Sophie Wang, Anuradha Budhu, William D. Figg, Maggie Cam, Richard Finney, Elliot B. Levy, David E. Kleiner, Seth M. Steinberg, Xin Wei Wang, Bernadette Redd, Bradford J. Wood, Tim F. Greten

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Phase I/II study of PexaVec in combination with immune checkpoint inhibition in refractory metastatic colorectal cancer by Stephen M Hewitt, David E Kleiner, Tim F Greten, William D Figg, Cecilia Monge, Seth M Steinberg, Maggie Cam, Benjamin Ruf, Austin G Duffy, Jonathan M Hernandez, Changqing Xie, Yuta Myojin, Kelley Coffman, Donna Mabry Hrones, Sophie Wang, Bradford J Wood, Elliot B Levy, Israa Juburi, Bernadette Redd, Philip Homan

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Society for Immunotherapy of Cancer (SITC) clinical practice guideline on immunotherapy for the treatment of hepatocellular carcinoma by Amaia Lujambio, Thomas Yau, Lipika Goyal, Andrew X Zhu, Ignacio Melero, Tim F Greten, Ann-Lii Cheng, Bruno Sangro, David J Pinato, Peter R Galle, Ghassan K Abou-Alfa, Austin G Duffy, Anthony B. El-Khoueiry, Richard S Finn, Aiwu Ruth He, Ahmed O Kaseb, Robin Kate Kelley, Riccardo Lencioni, Donna Mabry Hrones, Roberto I Troisi, Andrea Wilson Woods

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Genome-wide profiling of transcription factor activity in primary liver cancer using single-cell ATAC sequencing by Amanda J. Craig, Maruhen A. Datsch Silveira, Lichun Ma, Mahler Revsine, Limin Wang, Sophia Heinrich, Zachary Rae, Allison Ruchinskas, Kimia Dadkhah, Whitney Do, Shay Behrens, Farid R. Mehrabadi, Dana A. Dominguez, Marshonna Forgues, Anuradha Budhu, Jittiporn Chaisaingmongkol, Jonathan M. Hernandez, Jeremy L. Davis, Bao Tran, Jens U. Marquardt, Mathuros Ruchirawat, Michael Kelly, Tim F. Greten, Xin W. Wang

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