Human Pluripotent Stem Cells to Model Islet Defects in Diabetes by Diego Balboa, Diepiriye G. Iworima, Diepiriye G. Iworima, Timothy J. Kieffer, Timothy J. Kieffer, Timothy J. Kieffer

Get full text

Pancreatic islets in bed with microvasculature—companions for life by Corinne A. Hoesli, Timothy J. Kieffer

Get full text

Analysis of the effects of bench-scale cell culture platforms and inoculum cell concentrations on PSC aggregate formation and culture by Diepiriye G. Iworima, Diepiriye G. Iworima, Robert K. Baker, James M. Piret, James M. Piret, James M. Piret, Timothy J. Kieffer, Timothy J. Kieffer, Timothy J. Kieffer

Get full text

Restoration of Lepr in β cells of Lepr null mice does not prevent hyperinsulinemia and hyperglycemia by Anna M. D'souza, Timothy J. Kieffer

Get full text

Process parameter development for the scaled generation of stem cell‐derived pancreatic endocrine cells by Diepiriye G. Iworima, Sebastian Rieck, Timothy J. Kieffer

Get full text

Clinical Application of Glucagon-Like Peptide 1 Receptor Agonists for the Treatment of Type 2 Diabetes Mellitus by Young Min Cho, Rhonda D. Wideman, Timothy J. Kieffer

Get full text

Initial cell seeding density influences pancreatic endocrine development during in vitro differentiation of human embryonic stem cells. by Blair K Gage, Travis D Webber, Timothy J Kieffer

Get full text

Suppressing hyperinsulinemia prevents obesity but causes rapid onset of diabetes in leptin-deficient Lepob/ob mice by Anna M. D'souza, James D. Johnson, Susanne M. Clee, Timothy J. Kieffer

Get full text

Accelerated Maturation of Human Stem Cell-Derived Pancreatic Progenitor Cells into Insulin-Secreting Cells in Immunodeficient Rats Relative to Mice by Jennifer E. Bruin, Ali Asadi, Jessica K. Fox, Suheda Erener, Alireza Rezania, Timothy J. Kieffer

Get full text

FGF21-Mediated Improvements in Glucose Clearance Require Uncoupling Protein 1 by Michelle M. Kwon, Shannon M. O’Dwyer, Robert K. Baker, Scott D. Covey, Timothy J. Kieffer

Get full text

Attenuated secretion of glucose-dependent insulinotropic polypeptide (GIP) does not alleviate hyperphagic obesity and insulin resistance in ob/ob mice by Satoko Shimazu-Kuwahara, Norio Harada, Shunsuke Yamane, Erina Joo, Akiko Sankoda, Timothy J. Kieffer, Nobuya Inagaki

Get full text

Amyloid formation disrupts the balance between interleukin-1β and interleukin-1 receptor antagonist in human islets by Queenie Hui, Ali Asadi, Yoo Jin Park, Timothy J. Kieffer, Ziliang Ao, Garth L. Warnock, Lucy Marzban

Get full text

Glucagon receptor gene deletion in insulin knockout mice modestly reduces blood glucose and ketones but does not promote survival by Ursula H. Neumann, Jessica S.S. Ho, Majid Mojibian, Scott D. Covey, Maureen J. Charron, Timothy J. Kieffer

Get full text

Early overnutrition in male mice negates metabolic benefits of a diet high in monounsaturated and omega-3 fats by Maria M. Glavas, Queenie Hui, Ian Miao, Fan Yang, Suheda Erener, Kacey J. Prentice, Michael B. Wheeler, Timothy J. Kieffer

Get full text

Metabolic switching, growth kinetics and cell yields in the scalable manufacture of stem cell-derived insulin-producing cells by Diepiriye G. Iworima, Robert K. Baker, Cara Ellis, Chris Sherwood, Lisa Zhan, Alireza Rezania, James M. Piret, Timothy J. Kieffer

Get full text

Dipeptidyl peptidase-4 inhibitor treatment induces a greater increase in plasma levels of bioactive GIP than GLP-1 in non-diabetic subjects by Tsuyoshi Yanagimachi, Yukihiro Fujita, Yasutaka Takeda, Jun Honjo, Hidemitsu Sakagami, Hiroya Kitsunai, Yumi Takiyama, Atsuko Abiko, Yuichi Makino, Timothy J. Kieffer, Masakazu Haneda

Get full text

The Role of ARX in Human Pancreatic Endocrine Specification. by Blair K Gage, Ali Asadi, Robert K Baker, Travis D Webber, Rennian Wang, Masayuki Itoh, Masaharu Hayashi, Rie Miyata, Takumi Akashi, Timothy J Kieffer

Get full text

Characterization of polyhormonal insulin-producing cells derived in vitro from human embryonic stem cells by Jennifer E. Bruin, Suheda Erener, Javier Vela, Xiaoke Hu, James D. Johnson, Harley T. Kurata, Francis C. Lynn, James M. Piret, Ali Asadi, Alireza Rezania, Timothy J. Kieffer

Get full text

Protocol development to further differentiate and transition stem cell-derived pancreatic progenitors from a monolayer into endocrine cells in suspension culture by Mitchell J. S. Braam, Jia Zhao, Shenghui Liang, Shogo Ida, Nick K. Kloostra, Diepiriye G. Iworima, Mei Tang, Robert K. Baker, Nina Quiskamp, James M. Piret, Timothy J. Kieffer

Get full text

AAV GCG-EGFP, a new tool to identify glucagon-secreting α-cells by Eva Tudurí, Maria M. Glavas, Ali Asadi, Robert K. Baker, Cara E. Ellis, Galina Soukhatcheva, Marjolaine Philit, Frank K. Huynh, James D. Johnson, C. Bruce Verchere, Timothy J. Kieffer

Get full text