Type I Interferon in Human Autoimmunity by Timothy B. Niewold

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Nucleic Acid Sensors and Type I Interferon Production in Systemic Lupus Erythematosus by Meena eShrivastav, Timothy B. Niewold

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Activation of the Interferon Pathway is Dependent upon Autoantibodies to RNA-binding Proteins in African-American SLE Patients, but not in European-American SLE Patients by Kichul eKo, Yelena eKoldobskaya, Elizabeth eRosenzweig, Timothy B. Niewold

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905 Impact of the cGMP-dependent protein kinase I on the Rho-Kinase 2 signaling pathway and type I Interferon production by Timothy B Niewold, Ruth Fernandez-Ruiz, Justine Shum, Ilona Nln, Jacqueline L Paredes

High levels of circulating interferons type I, type II and type III associate with distinct clinical features of active systemic lupus erythematosus by Vilija Oke, Iva Gunnarsson, Jessica Dorschner, Susanna Eketjäll, Agneta Zickert, Timothy B. Niewold, Elisabet Svenungsson

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Interleukin (IL) 16: a candidate urinary biomarker for proliferative lupus nephritis by Anders Larsson, Elisabet Svenungsson, Timothy B Niewold, Iva Gunnarsson, Agneta Zickert, Vilija Oke, Aliisa Häyry

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Dysregulation of Antiviral Helicase Pathways in Systemic Lupus Erythematosus by Luciana eOliveira, Nailú Angélica eSinicato, Mariana ePostal, Simone eAppenzeller, Timothy B. Niewold

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P18 Proteomic analysis of cutaneous lupus erythematosus (CLE) dermal infiltrates and control skin reveals differentially upregulated and downregulated pathways by Elisabet Svenungsson, Timothy B Niewold, Vilija Oke, Surendra Dasari, Alexander Meves, Julia Lehman, Karin Popovic-Silwerfeldt, Benjamin Madden, Cristine Charlesworth

LSO-039 Proteomic analysis of cutaneous lupus erythematosus and dermatomyositis dermal infiltrate reveals differentially expressed canonical pathways by Elisabet Svenungsson, Timothy B Niewold, Vilija Oke, Alexander Meves, Karin Popovic-Silwerfeldt, Cristine M Charlesworth, Aliisa Häyry, Julia S Lehman, Benjamin Madden

A Clinically and Biologically Based Subclassification of the Idiopathic Inflammatory Myopathies Using Machine Learning by Simon W. M. Eng, Jeannette M. Olazagasti, Anna Goldenberg, Cynthia S. Crowson, Chester V. Oddis, Timothy B. Niewold, Rae S. M. Yeung, Ann M. Reed

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1005 Characterization of regulatory receptors on plasmacytoid dendritic cells in lupus by Taro Iwamoto, Timothy B Niewold, Jessica M Dorschner, Mark A Jensen, Danielle M Vsetecka, Ilona Nln, Jacqueline L Paredes, Gabrielle A McCoy

Relationship of systemic type I interferon activity with clinical phenotypes, disease activity, and damage accrual in systemic lupus erythematosus in treatment-naive patients: a re... by Kazusa Miyachi, Taro Iwamoto, Shotaro Kojima, Tomoaki Ida, Junya Suzuki, Takuya Yamamoto, Norihiro Mimura, Takahiro Sugiyama, Shigeru Tanaka, Shunsuke Furuta, Kei Ikeda, Kotaro Suzuki, Timothy B. Niewold, Hiroshi Nakajima

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Proteome study of cutaneous lupus erythematosus (CLE) and dermatomyositis skin lesions reveals IL-16 is differentially upregulated in CLE by Timothy B. Niewold, Alexander Meves, Julia S. Lehman, Karin Popovic-Silwerfeldt, Aliisa Häyry, Therese Söderlund-Matell, Cristine M. Charlesworth, Benjamin Madden, Ingrid E. Lundberg, Marie Wahren-Herlenius, Elisabet Svenungsson, Vilija Oke

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Increased serum type I interferon activity in organ specific autoimmune disorders: Clinical, imaging and serological associations by Clio eMavragani, Clio eMavragani, Timothy B. Niewold, Antonis eChatzigeorgiou, Stamatina eDanielides, Dimitris eThomas, Kyriakos eKirou, Elli eKamper, Gregory A Kaltsas, Mary eCrow

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Significant CD4, CD8, and CD19 lymphopenia in peripheral blood of sarcoidosis patients correlates with severe disease manifestations. by Nadera J Sweiss, Rafah Salloum, Seema Gandhi, Maria-Luisa Alegre, Ray Sawaqed, Maria Badaracco, Kenneth Pursell, David Pitrak, Robert P Baughman, David R Moller, Joe G N Garcia, Timothy B Niewold

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Autoantibody repertoire characterization provides insight into the pathogenesis of monogenic and polygenic autoimmune diseases by Thomas Clarke, Pan Du, Satyendra Kumar, Shinji L. Okitsu, Mark Schuette, Qi An, Jinyang Zhang, Evgeni Tzvetkov, Mark A. Jensen, Timothy B. Niewold, Elise M. N. Ferre, Julie Nardone, Michail S. Lionakis, Jaromir Vlach, Julie DeMartino, Andrew T. Bender

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Single-cell expression quantitative trait loci (eQTL) analysis of SLE-risk loci in lupus patient monocytes by Yogita Ghodke-Puranik, Zhongbo Jin, Kip D. Zimmerman, Hannah C. Ainsworth, Wei Fan, Mark A. Jensen, Jessica M. Dorschner, Danielle M. Vsetecka, Shreyasee Amin, Ashima Makol, Floranne Ernste, Thomas Osborn, Kevin Moder, Vaidehi Chowdhary, Carl D. Langefeld, Timothy B. Niewold

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Ribosomal and immune transcripts associate with relapse in acquired ADAMTS13-deficient thrombotic thrombocytopenic purpura. by Contessa E Edgar, Deirdra R Terrell, Sara K Vesely, Jonathan D Wren, Igor M Dozmorov, Timothy B Niewold, Michael Brown, Fang Zhou, Mark Barton Frank, Joan T Merrill, Johanna A Kremer Hovinga, Bernhard Lämmle, Judith A James, James N George, A Darise Farris

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Distinct Single Cell Gene Expression in Peripheral Blood Monocytes Correlates With Tumor Necrosis Factor Inhibitor Treatment Response Groups Defined by Type I Interferon in Rheumat... by Theresa L. Wampler Muskardin, Theresa L. Wampler Muskardin, Wei Fan, Zhongbo Jin, Mark A. Jensen, Mark A. Jensen, Jessica M. Dorschner, Yogita Ghodke-Puranik, Yogita Ghodke-Puranik, Betty Dicke, Danielle Vsetecka, Kerry Wright, Thomas Mason, Scott Persellin, Clement J. Michet, John M. Davis, Eric Matteson, Timothy B. Niewold

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Admixture mapping in lupus identifies multiple functional variants within IFIH1 associated with apoptosis, inflammation, and autoantibody production. by Julio E Molineros, Amit K Maiti, Celi Sun, Loren L Looger, Shizhong Han, Xana Kim-Howard, Stuart Glenn, Adam Adler, Jennifer A Kelly, Timothy B Niewold, Gary S Gilkeson, Elizabeth E Brown, Graciela S Alarcón, Jeffrey C Edberg, Michelle Petri, Rosalind Ramsey-Goldman, John D Reveille, Luis M Vilá, Barry I Freedman, Betty P Tsao, Lindsey A Criswell, Chaim O Jacob, Jason H Moore, Timothy J Vyse, Carl L Langefeld, Joel M Guthridge, Patrick M Gaffney, Kathy L Moser, R Hal Scofield, Marta E Alarcón-Riquelme, BIOLUPUS Network, Scott M Williams, Joan T Merrill, Judith A James, Kenneth M Kaufman, Robert P Kimberly, John B Harley, Swapan K Nath

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