Efficacy of central nervous system prophylaxis with stand-alone intrathecal chemotherapy in diffuse large B-cell lymphoma patients treated with anthracycline-based chemotherapy in... by Toby A. Eyre, Faouzi Djebbari, Amy A. Kirkwood, Graham P. Collins

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Complete response of mantle cell lymphoma with central nervous system involvement at diagnosis with acalabrutinib – Case report by Aisling Barrett, Toby A. Eyre, Shaheel Bhuva, Mahmoud Aljurf, Riad El Fakih, Mohammad A. Ashshi, Alfadel Alshaibani

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Pirtobrutinib <i>versus</i> venetoclax in covalent Bruton tyrosine kinase inhibitor-pretreated chronic lymphocytic leukemia: a matching-adjusted indirect comparison by Othman Al-Sawaf, Min-Hua Jen, Lisa M Hess, Jiewen Zhang, Benjamin Goebel, John M. Pagel, Sarang Abhyankar, Matthew S. Davids, Toby A. Eyre

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Infection-related morbidity in a large study of transplant non-eligible newly diagnosed myeloma patients treated with UK standard of care by Faouzi Djebbari, Fotios Panitsas, Toby A. Eyre, Catherine Prodger, Fearn Davies, Kieran Burton, Akhil Khera, Grant Vallance, Sally Moore, Jaimal Kothari, Andy Peniket, Karthik Ramasamy

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Efficacy of venetoclax monotherapy in patients with relapsed, refractory mantle cell lymphoma after Bruton tyrosine kinase inhibitor therapy by Toby A. Eyre, Harriet S. Walter, Sunil Iyengar, George Follows, Matthew Cross, Christopher P. Fox, Andrew Hodson, Josh Coats, Santosh Narat, Nick Morley, Martin J.S. Dyer, Graham P. Collins

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P618: LONG-TERM SAFETY WITH ≥12 MONTHS OF PIRTOBRUTINIB IN RELAPSED/REFRACTORY (R/R) B-CELL MALIGNANCIES by Wojciech Jurczak, Catherine C. Coombs, Nirav N. Shah, Jennifer Woyach, Chan Y. Cheah, Krish Patel, Kami Maddocks, Yucai Wang, Catherine E. Muehlenbein, Chunxiao Wang, Sarang Abhyankar, Donald E. Tsai, Toby A. Eyre

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Pirtobrutinib results in reversible platelet dysfunction compared to ibrutinib and acalabrutinib by Alexander P. Bye, Neline Kriek, Tanya Sage, Suzannah J. Rawlings, Catherine Prodger, Murali Kesavan, Charlotte Lees, Stephen Booth, Louise G. Cowen, Kirsty Shefferd, Michael J. Desborough, Jonathan M. Gibbins, Toby A. Eyre

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Impact of positron emission tomography - computed tomography status on progression-free survival for relapsed follicular lymphoma patients undergoing autologous stem cell transplan... by Toby A. Eyre, Sally F. Barrington, Jessica Okosun, Clementina Abamba, Rachel M. Pearce, Julia Lee, Ben Carpenter, Charles R. Crawley, Adrian J.C. Bloor, Maria Gilleece, Emma Nicholson, Nimish Shah, Kim Orchard, Ram Malladi, William M. Townsend

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Outcome of COVID-19 in Patients With Mantle Cell Lymphoma—Report From the European MCL Registry by Marie-Kristin Tilch, Carlo Visco, Sandra Kinda, Olivier Hermine, Milena Kohn, Caroline Besson, Sylvain Lamure, Rémy Duléry, Simone Ragaini, Toby A. Eyre, Tom Van Meerten, Anke Ohler, Steffen Eckerle, Martin Dreyling, Georg Hess, Eva Giné, Maria Gomes da Silva

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P1095: COVID-19 VACCINE RESPONSES IN FOLLICULAR LYMPHOMA: DETERMINANTS OF HUMORAL AND CELLULAR IMMUNITY IN THE PETREA TRIAL OF FRONTLINE CHEMOIMMUNOTHERAPY by Yeong Jer Lim, Victoria Ward, Liam Farrell, Dean Naisbitt, Anthony Brown, Eloise Phillips, Paul Thomson, Melanie Oates, Richard Jackson, Andrew Morrison, Matthew Burns, Paul Klenerman, Lance Turtle, Malcolm Rhodes, Kate Robinson, Simona Gatto, Moya Young, Toby A Eyre, David W. Eyre, Susanna Dunachie, Eleanor Barnes, Andrew Pettitt

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A Phase II Study to Assess the Safety and Efficacy of the Dual mTORC1/2 and PI3K Inhibitor Bimiralisib (PQR309) in Relapsed, Refractory Lymphoma by Graham P. Collins, Toby A. Eyre, Debora Schmitz-Rohmer, William Townsend, Rakesh Popat, Lisa Giulino-Roth, Paul A. Fields, Fatime Krasniqi, Carole Soussain, Anastasios Stathis, Nebojsa Andjelkovic, David Cunningham, Danijela Mandic, Sinisa Radulovic, Ivan Tijanic, Netanel A. Horowitz, Sabira Kurtovic, Elisabeth Schorb, Christian Schmidt, Saša Dimitrijević, Martin Dreyling

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P1087: PIRTOBRUTINIB IN COVALENT BTK-INHIBITOR PRE-TREATED MANTLE CELL LYMPHOMA: UPDATED RESULTS AND SUBGROUP ANALYSIS FROM THE PHASE 1/2 BRUIN STUDY WITH >3 YEARS FOLLOW-UP FROM S... by Wojciech Jurczak, Pier Luigi Zinzani, Toby A. Eyre, Chan Y. Cheah, Chaitra S. Ujjani, Koji Izutsu, Shuo MA, Ian Flinn, Alvaro J. Alencar, David Lewis, Krish Patel, Kami Maddocks, Yucai Wang, Talha Munir, Andrew D. Zelenetz, Minna Balbas, Donald E. Tsai, Chunxiao Wang, Michael L. Wang, Nirav N. Shah

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P1102: IBRUTINIB AND RITUXIMAB AS FIRST LINE THERAPY FOR MANTLE CELL LYMPHOMA: UPDATED OUTCOMES FROM A MULTICENTRE, REAL-WORLD UK STUDY by Rohan Shotton, Ann Tivey, Toby A. Eyre, David Lewis, Rebecca Allchin, Harriet Walter, Fiona Miall, Rui Zhao, Anna Santarsieri, Rory Mcculloch, Mark Bishton, Victoria Willimott, Nicole Fowler, Claudia Bedford, Jack Goddard, Samuel Protheroe, Mahesh Prahladan, Miriam Reeve, Shankara Paneesha, Helen Marr, Jamie Wilson, Kushani Ediriwickrema, Chloe Knott, David Wrench, Georgina Talbot, Kim Linton

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A retrospective study of MYC rearranged diffuse large B-cell lymphoma in the context of the new WHO and ICC classifications by Dima El-Sharkawi, Amit Sud, Catherine Prodger, Jahanzaib Khwaja, Rohan Shotton, Brian Hanley, Victoria Peacock, Ying Ying Peng, Anita Arasaretnam, Sarkhara Sharma, Frances Aldridge, Bhupinder Sharma, Andrew Wotherspoon, Betty Cheung, Corinne De Lord, Rosalynd Johnston, Shireen Kassam, Ruth Pettengel, Kim Linton, Paul Greaves, Lucy Cook, Kikkeri N. Naresh, Kate Cwynarski, Toby A. Eyre, Ian Chau, David Cunningham, Sunil Iyengar

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International multicenter retrospective analysis of thiotepa-based autologous stem cell transplantation for secondary central nervous system lymphoma by Jahanzaib Khwaja, Amy A. Kirkwood, Lisa K. Isbell, Sara Steffanoni, Harshita Goradia, Lisa Pospiech, Thomas Fail, Emma Nicholson, Kate Fletcher, Kim M. Linton, Katrina E. Parsons, Nagah Elmusharaf, Lydia Eccersley, Toby A. Eyre, Sridhar Chaganti, Jeffrey Smith, Nisha Thakrar, Alexandra Kutilina, Teresa Calimeri, Nicolas Martinez-Calle, Dima El-Sharkawi, Wendy Osborne, Gerald Illerhaus, Christopher P. Fox, Andrés J.M. Ferreri, Elisabeth Schorb, Kate Cwynarski

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P648: REAL-WORLD TREATMENT AND OUTCOMES OF PATIENTS WITH CHRONIC LYMPHOCYTIC LEUKEMIA (CLL) RECEIVING FIRST-LINE (1L) THERAPY IN THE NOVEL AGENT ERA: AN INTERNATIONAL STUDY by Frederick Lansigan, Toby A. Eyre, Nilanjan Ghosh, Beenish S. Manzoor, Catherine C. Coombs, Nicole Lamanna, Hande H. Tuncer, Dozie Emechebe, Jennifer R. Brown, Lindsey E. Roeker, Chaitra Ujjani, Hasan Alhasani, Isabelle Fleury, Lori A. Leslie, Alan Skarbnik, Joanna Rhodes, Brian T. Hill, Paul M. Barr, Matthew S. Davids, Christopher P. Fox, Yun Choi, Anna Schuh, Kaitlin Kennard, Christopher E. Jensen, Dureshahwar Jawaid, Aditya Sharma, Irina Pivneva, Talissa Watson, Mazyar Shadman

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Comparative analysis of targeted novel therapies in relapsed, refractory chronic lymphocytic leukaemia by Toby A. Eyre, Nicole Lamanna, Lindsey E. Roeker, Chaitra S. Ujjani, Brian T. Hill, Paul M. Barr, Erick Lansigan, Bruce D. Cheson, Maryam Yazdy, John N. Allan, Joanna Rhodes, Stephen J. Schuster, Chadi Nabhan, Alan Skarbnik, Lori Leslie, Prioty Islam, Katherine Whitaker, Catherine C. Coombs, Hande H. Tuncer, John M. Pagel, Ryan Jacobs, Allison M. Winter, Neil Bailey, Andrea Sitlinger, Anna H. Schuh, George Follows, Christopher P. Fox, Danielle M. Brander, Mazyar Shadman, Anthony R. Mato

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P1108: EFFICACY OF PIRTOBRUTINIB, A HIGHLY SELECTIVE, NON-COVALENT (REVERSIBLE) BTK INHIBITOR IN RELAPSED/REFRACTORY WALDENSTRÖM MACROGLOBULINEMIA: RESULTS FROM THE PHASE 1/2 BRUIN... by Lydia Scarfò, Manish R. Patel, Toby A. Eyre, Wojciech Jurczak, David Lewis, Thomas Gastinne, Shuo MA, Jonathon B. Cohen, Krish Patel, Jennifer R. Brown, Talha Munir, Ewa Lech-Maranda, Marc S. Hoffmann, Chaitra S. Ujjani, Bita Fakhri, Michael Wang, Koji Izutsu, Hirokazu Nagai, Constantine S. Tam, John F. Seymour, Joanna Rhodes, Julie Vose, Matthew Mckinney, James N. Gerson, Minal A. Barve, Bryone Kuss, Youngil Koh, Wei Gao, Amy S. Ruppert, Richard A. Walgren, Donald E. Tsai, Binoj Nair, Katherine Bao, Anthony R. Mato, Chan Y. Cheah, M Lia Palomba

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Pirtobrutinib monotherapy in Bruton tyrosine kinase inhibitor-intolerant patients with B-cell malignancies: results of the phase I/II BRUIN trial by Nirav N. Shah, Michael Wang, Lindsey E. Roeker, Krish Patel, Jennifer A. Woyach, William G. Wierda, Chaitra S. Ujjani, Toby A. Eyre, Pier Luigi Z inzani, Alvaro J. Alencar, Paolo Ghia, Nicole Lamanna, Marc S. Hoffmann, Manish R. Patel, Ian Flinn, James N. Gerson, Shuo Ma, Catherine C. Coombs, Chan Y. Cheah, Ewa Lech-Maranda, Bita Fakhri, Won Seog Kim, Minal A. Barve, Jonathon B. Cohen, Wojciech Jurczak, Talha Munir, Meghan C. Thompson, Donald E. Tsai, Katherine Bao, Nicholas A. Cangemi, Jennifer F. Kherani, Richard A. Walgren, Hongmei Han, Amy S. Ruppert, Jennifer R. Brown

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Efficacy of bendamustine and rituximab as first salvage treatment in chronic lymphocytic leukemia and indirect comparison with ibrutinib: a GIMEMA, ERIC and UK CLL FORUM study by Antonio Cuneo, George Follows, Gian Matteo Rigolin, Alfonso Piciocchi, Alessandra Tedeschi, Livio Trentin, Angeles Medina Perez, Marta Coscia, Luca Laurenti, Gerardo Musuraca, Lucia Farina, Alfredo Rivas Delgado, Ester Maria Orlandi, Piero Galieni, Francesca Romana Mauro, Carlo Visco, Angela Amendola, Atto Billio, Roberto Marasca, Annalisa Chiarenza, Vittorio Meneghini, Fiorella Ilariucci, Monia Marchetti, Stefano Molica, Francesca Re, Gianluca Gaidano, Marcos Gonzalez, Francesco Forconi, Stefania Ciolli, Agostino Cortelezzi, Marco Montillo, Lukas Smolej, Anna Schuh, Toby A. Eyre, Ben Kennedy, Kris M. Bowles, Marco Vignetti, Javier de la Serna, Carol Moreno, Robin Foà, Paolo Ghia

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