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PARP1-SNAI2 transcription axis drives resistance to PARP inhibitor, Talazoparib by Xia Ding, Zhou Zhu, John Lapek, Elizabeth A. McMillan, Alexander Zhang, Chi-Yeh Chung, Sara Dubbury, Jennifer Lapira, Sarah Firdaus, Xiaolin Kang, Jingjin Gao, Jon Oyer, John Chionis, Robert A. Rollins, Lianjie Li, Sherry Niessen, Shubha Bagrodia, Lianglin Zhang, Todd VanArsdale

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Multimodal perturbation analyses of cyclin-dependent kinases reveal a network of synthetic lethalities associated with cell-cycle regulation and transcriptional regulation by Kyle Ford, Brenton P. Munson, Samson H. Fong, Rebecca Panwala, Wai Keung Chu, Joseph Rainaldi, Nongluk Plongthongkum, Vinayagam Arunachalam, Jarek Kostrowicki, Dario Meluzzi, Jason F. Kreisberg, Kristen Jensen-Pergakes, Todd VanArsdale, Thomas Paul, Pablo Tamayo, Kun Zhang, Jadwiga Bienkowska, Prashant Mali, Trey Ideker

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Antitumor Efficacy of the Dual PI3K/mTOR Inhibitor PF-04691502 in a Human Xenograft Tumor Model Derived from Colorectal Cancer Stem Cells Harboring a PIK3CA Mutation. by Douglas D Fang, Cathy C Zhang, Yin Gu, Jitesh P Jani, Joan Cao, Konstantinos Tsaparikos, Jing Yuan, Melissa Thiel, Amy Jackson-Fisher, Qing Zong, Patrick B Lappin, Tomoko Hayashi, Richard B Schwab, Anthony Wong, Annette John-Baptiste, Shubha Bagrodia, Geritt Los, Steve Bender, James Christensen, Todd Vanarsdale

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A versatile drug delivery system targeting senescent cells by Daniel Muñoz‐Espín, Miguel Rovira, Irene Galiana, Cristina Giménez, Beatriz Lozano‐Torres, Marta Paez‐Ribes, Susana Llanos, Selim Chaib, Maribel Muñoz‐Martín, Alvaro C Ucero, Guillermo Garaulet, Francisca Mulero, Stephen G Dann, Todd VanArsdale, David J Shields, Andrea Bernardos, José Ramón Murguía, Ramón Martínez‐Máñez, Manuel Serrano

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