ScFv anti-heparan sulfate antibodies unexpectedly activate endothelial and cancer cells through p38 MAPK: implications for antibody-based targeting of heparan sulfate proteoglycans... by Helena C Christianson, Toin H van Kuppevelt, Mattias Belting

Get full text

Biphasic role of chondroitin sulfate in cardiac differentiation of embryonic stem cells through inhibition of Wnt/β-catenin signaling. by Robert D Prinz, Catherine M Willis, Toin H van Kuppevelt, Michael Klüppel

Get full text

3-O-sulfated heparan sulfate recognized by the antibody HS4C3 contributes [corrected] to the differentiation of mouse embryonic stem cells via fas signaling. by Kazumi Hirano, Norihiko Sasaki, Tomomi Ichimiya, Taichi Miura, Toin H Van Kuppevelt, Shoko Nishihara

Get full text

Correction: 3--Sulfated Heparan Sulfate Recognized by the Antibody HS4C3 Contribute to the Differentiation of Mouse Embryonic Stem Cells via Fas Signaling. by Kazumi Hirano, Norihiko Sasaki, Tomomi Ichimiya, Taichi Miura, Toin H. Van Kuppevelt, Shoko Nishihara

Get full text

Drug delivery systems for ovarian cancer treatment: a systematic review and meta-analysis of animal studies by René Raavé, Rob B.M. de Vries, Leon F. Massuger, Toin H. van Kuppevelt, Willeke F. Daamen

Get full text

The role of MMP-14 in ovarian cancer: a systematic review by M. Caroline Vos, Anneke A. M. van der Wurff, Toin H. van Kuppevelt, Leon F. A. G. Massuger

Get full text

Dermatan Sulfate-Free Mice Display Embryological Defects and Are Neonatal Lethal Despite Normal Lymphoid and Non-Lymphoid Organogenesis. by Xanthi N Stachtea, Emil Tykesson, Toin H van Kuppevelt, Ricardo Feinstein, Anders Malmström, Rogier M Reijmers, Marco Maccarana

Get full text

Primary ovarian carcinomas and abdominal metastasis contain 4,6-disulfated chondroitin sulfate rich regions, which provide adhesive properties to tumour cells. by Myrtille J E Vallen, Samuel Schmidt, Arie Oosterhof, Johan Bulten, Leon F A G Massuger, Toin H van Kuppevelt

Get full text

Iduronic acid in chondroitin/dermatan sulfate affects directional migration of aortic smooth muscle cells. by Barbara Bartolini, Martin A Thelin, Martin A Thelin, Lena Svensson, Giancarlo Ghiselli, Toin H van Kuppevelt, Anders Malmström, Marco Maccarana

Get full text

Initial Steps towards Spatiotemporal Signaling through Biomaterials Using Click-to-Release Chemistry by Merel Gansevoort, Jona Merx, Elly M. M. Versteeg, Isidora Vuckovic, Thomas J. Boltje, Toin H. van Kuppevelt, Willeke F. Daamen

Get full text

Introduction of Specific 3D Micromorphologies in Collagen Scaffolds Using Odd and Even Dicarboxylic Acids by Michiel W. Pot, Silvia M. Mihaila, Dana te Brinke, Guus van der Borg, Egbert Oosterwijk, Willeke F. Daamen, Toin H. van Kuppevelt

Get full text

Augmented cartilage regeneration by implantation of cellular versus acellular implants after bone marrow stimulation: a systematic review and meta-analysis of animal studies by Michiel W. Pot, Toin H. van Kuppevelt, Veronica K. Gonzales, Pieter Buma, Joanna IntHout, Rob B.M. de Vries, Willeke F. Daamen

Get full text

Improved cartilage regeneration by implantation of acellular biomaterials after bone marrow stimulation: a systematic review and meta-analysis of animal studies by Michiel W. Pot, Veronica K. Gonzales, Pieter Buma, Joanna IntHout, Toin H. van Kuppevelt, Rob B.M. de Vries, Willeke F. Daamen

Get full text

Sulf1 and Sulf2 Differentially Modulate Heparan Sulfate Proteoglycan Sulfation during Postnatal Cerebellum Development: Evidence for Neuroprotective and Neurite Outgrowth Promoting... by Ina Kalus, Susanne Rohn, Tania M Puvirajesinghe, Scott E Guimond, Pieter J Eyckerman-Kölln, Gerdy Ten Dam, Toin H van Kuppevelt, Jeremy E Turnbull, Thomas Dierks

Get full text

Gene expression profiles in mesenchymal stromal cells from bone marrow, adipose tissue and lung tissue of COPD patients and controls by Dennis Kruk, Anna C. Y. Yeung, Alen Faiz, Nick H. T. ten Hacken, Wim Timens, Toin H. van Kuppevelt, Willeke Daamen, Danique Hof, Martin C. Harmsen, Mauricio Rojas, Irene H. Heijink

Get full text

Heparin-resistance in AL amyloidosis: a case report by Elisabeth S. van Ede, Marlijn P. A. Hoeks, Jan Hofland, Vera D. Linssen, Toin H. van Kuppevelt, Elly M. Versteeg, Theo G. Hafmans, Arjan Diepstra, Benno Kusters, Sanne M. M. Vermorgen

Get full text

Selective Binding of Heparin/Heparan Sulfate Oligosaccharides to Factor H and Factor H-Related Proteins: Therapeutic Potential for C3 Glomerulopathies by Markus A. Loeven, Marissa L. Maciej-Hulme, Cansu Yanginlar, Melanie C. Hubers, Edwin Kellenbach, Mark de Graaf, Toin H. van Kuppevelt, Jack Wetzels, Ton J. Rabelink, Richard J. H. Smith, Johan van der Vlag

Get full text

Blocking of inflammatory heparan sulfate domains by specific antibodies is not protective in experimental glomerulonephritis. by Jasper J van Gemst, Nathalie J H G Passmann, Angelique L W M M Rops, Toin H van Kuppevelt, Jo H Berden, Markus A Loeven, Ton J Rabelink, Bart Smeets, Johan van der Vlag

Get full text

Distinct osmoregulatory responses to sodium loading in patients with altered glycosaminoglycan structure: a randomized cross-over trial by Eliane F. E. Wenstedt, Jetta J. Oppelaar, Stijn Besseling, Nienke M. G. Rorije, Rik H. G. Olde Engberink, Arie Oosterhof, Toin H. van Kuppevelt, Bert-Jan H. van den Born, Jan Aten, Liffert Vogt

Get full text

Differential Expression of Specific Dermatan Sulfate Domains in Renal Pathology. by Joost F M Lensen, Johan van der Vlag, Elly M M Versteeg, Jack F M Wetzels, Lambert P W J van den Heuvel, Jo H M Berden, Toin H van Kuppevelt, Angelique L W M M Rops

Get full text