The End of “One Size Fits All” Sepsis Therapies: Toward an Individualized Approach by Jean-Louis Vincent, Tom van der Poll, John C. Marshall

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No evidence for relevant impact of renal replacement therapy on clinical effect of erythromycin in critically ill patients with sepsis by Tom D. Y. Reijnders, Hessel Peters-Sengers, Tom van der Poll

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Bradykinin receptor deficiency or antagonism do not impact the host response during gram-negative pneumonia-derived sepsis by Chao Ding, Jack Yang, Cornelis van’t Veer, Tom van der Poll

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Tenascin-C Deficiency Is Associated With Reduced Bacterial Outgrowth During Klebsiella pneumoniae-Evoked Pneumosepsis in Mice by Mariska T. Meijer, Mariska T. Meijer, Alex F. de Vos, Alex F. de Vos, Brendon P. Scicluna, Brendon P. Scicluna, Brendon P. Scicluna, Joris J. Roelofs, Chérine Abou Fayçal, Gertraud Orend, Fabrice Uhel, Fabrice Uhel, Tom van der Poll, Tom van der Poll, Tom van der Poll

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Glucose metabolism is upregulated in the mononuclear cell proteome during sepsis and supports endotoxin-tolerant cell function by Bianca Lima Ferreira, Mônica Bragança Sousa, Giuseppe Gianini Figueirêdo Leite, Milena Karina Colo Brunialti, Erika Sayuri Nishiduka, Alexandre Keiji Tashima, Tom van der Poll, Tom van der Poll, Reinaldo Salomão

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Embracing complexity in sepsis by Alex R. Schuurman, Peter M. A. Sloot, W. Joost Wiersinga, Tom van der Poll

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MyD88 dependent signaling contributes to protective host defense against Burkholderia pseudomallei. by W Joost Wiersinga, Catharina W Wieland, Joris J T H Roelofs, Tom van der Poll

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Host-pathogen interaction in invasive Salmonellosis. by Hanna K de Jong, Chris M Parry, Tom van der Poll, W Joost Wiersinga

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Role of Toll-like receptors 2 and 4 in pulmonary inflammation and injury induced by pneumolysin in mice. by Mark C Dessing, Robert A Hirst, Alex F de Vos, Tom van der Poll

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Myeloid DNA methyltransferase3b deficiency aggravates pulmonary fibrosis by enhancing profibrotic macrophage activation by Wanhai Qin, C. Arnold Spek, Brendon P. Scicluna, Tom van der Poll, JanWillem Duitman

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Concurrent Immune Suppression and Hyperinflammation in Patients With Community-Acquired Pneumonia by Xanthe Brands, Bastiaan W. Haak, Augustijn M. Klarenbeek, Natasja A. Otto, Daniël R. Faber, René Lutter, Brendon P. Scicluna, Brendon P. Scicluna, W. Joost Wiersinga, W. Joost Wiersinga, Tom van der Poll, Tom van der Poll

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Bruton’s Tyrosine Kinase-Mediated Signaling in Myeloid Cells Is Required for Protective Innate Immunity During Pneumococcal Pneumonia by Alexander P. de Porto, Zhe Liu, Zhe Liu, Regina de Beer, Regina de Beer, Sandrine Florquin, Joris J. T. H. Roelofs, Onno J. de Boer, Joke M. M. den Haan, Rudi W. Hendriks, Cornelis van ‘t Veer, Cornelis van ‘t Veer, Tom van der Poll, Tom van der Poll, Tom van der Poll, Alex F. de Vos, Alex F. de Vos

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Myeloid liver kinase B1 contributes to lung inflammation induced by lipoteichoic acid but not by viable Streptococcus pneumoniae by Liza Pereverzeva, Natasja A. Otto, Joris J. T. H. Roelofs, Alex F. de Vos, Tom van der Poll

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Role of CD14 in a mouse model of acute lung inflammation induced by different lipopolysaccharide chemotypes. by Adam A Anas, Joppe W R Hovius, Cornelis van 't Veer, Tom van der Poll, Alex F de Vos

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DNA Methyltransferase 3b in Myeloid Cells Does Not Affect the Acute Immune Response in the Airways during <i>Pseudomonas</i> Pneumonia by Wanhai Qin, Xanthe Brands, Cornelis van’t Veer, Alex F. de Vos, Brendon P. Scicluna, Tom van der Poll

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Role of tumor necrosis factor-α in the human systemic endotoxin-induced transcriptome. by Brendon P Scicluna, Cornelis van 't Veer, Max Nieuwdorp, Karen Felsmann, Britta Wlotzka, Erik S G Stroes, Tom van der Poll

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High-dimensional phenotyping of the peripheral immune response in community-acquired pneumonia by Tom D. Y. Reijnders, Alex R. Schuurman, Jan Verhoeff, Marlous van den Braber, Renée A. Douma, Daniël R. Faber, Alberta G. A. Paul, W. Joost Wiersinga, W. Joost Wiersinga, Anno Saris, Juan J. Garcia Vallejo, Tom van der Poll, Tom van der Poll

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Combined Transcriptome and Proteome Leukocyte’s Profiling Reveals Up-Regulated Module of Genes/Proteins Related to Low Density Neutrophils and Impaired Transcription and Translatio... by Giuseppe Gianini Figueirêdo Leite, Bianca Lima Ferreira, Alexandre Keiji Tashima, Erika Sayuri Nishiduka, Edecio Cunha-Neto, Milena Karina Colo Brunialti, Murillo Assuncao, Luciano Cesar Pontes Azevedo, Flávio Freitas, Tom van der Poll, Tom van der Poll, Brendon P. Scicluna, Brendon P. Scicluna, Reinaldo Salomão

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Effect of antibiotic gut microbiota disruption on LPS-induced acute lung inflammation. by Max C Jacobs, Jacqueline M Lankelma, Nora S Wolff, Floor Hugenholtz, Alex F de Vos, Tom van der Poll, W Joost Wiersinga

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Sepsis: deriving biological meaning and clinical applications from high-dimensional data by Alex R. Schuurman, Tom D. Y. Reijnders, Robert F. J. Kullberg, Joe M. Butler, Tom van der Poll, W. Joost Wiersinga

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