Furin is the major proprotein convertase required for KISS1-to-Kisspeptin processing. by Sitaram Harihar, Keke M Pounds, Tomoo Iwakuma, Nabil G Seidah, Danny R Welch

Get full text

DNAJA1- and conformational mutant p53-dependent inhibition of cancer cell migration by a novel compound identified through a virtual screen by Shigeto Nishikawa, Atsushi Kaida, Alejandro Parrales, Atul Ranjan, Mohamed Alalem, Hongyi Ren, Frank J. Schoenen, David K. Johnson, Tomoo Iwakuma

Get full text

Suppressing STAT5 signaling affects osteosarcoma growth and stemness by Dharmalingam Subramaniam, Pablo Angulo, Sivapriya Ponnurangam, Prasad Dandawate, Prabhu Ramamoorthy, Pugazhendhi Srinivasan, Tomoo Iwakuma, Scott J. Weir, Katherine Chastain, Shrikant Anant

Get full text

Genome-wide RNAi screening identifies TMIGD3 isoform1 as a suppressor of NF-κB and osteosarcoma progression by Swathi V. Iyer, Atul Ranjan, Harold K. Elias, Alejandro Parrales, Hiromi Sasaki, Badal C. Roy, Shahid Umar, Ossama W. Tawfik, Tomoo Iwakuma

Get full text

Comparative oncology approach to drug repurposing in osteosarcoma. by Alejandro Parrales, Peter McDonald, Megan Ottomeyer, Anuradha Roy, Frank J Shoenen, Melinda Broward, Tyce Bruns, Douglas H Thamm, Scott J Weir, Kathleen A Neville, Tomoo Iwakuma, Joy M Fulbright

Get full text

A modified nucleoside O6-methyl-2′-deoxyguanosine-5′-triphosphate exhibits anti-glioblastoma activity in a caspase-independent manner by Zi-Hui Wang, Jin Li, Qian Liu, Jian-Chang Qian, Qing-Qing Li, Qing-Yu Wang, Lv-Tao Zeng, Si-Jia Li, Xin Gao, Jia-Xin Pan, Xu-Fan Gao, Kun Wu, Guo-Xin Hu, Tomoo Iwakuma, Jian-Ping Cai

Get full text