HIF overexpression correlates with biallelic loss of fumarate hydratase in renal cancer: novel role of fumarate in regulation of HIF stability. by Isaacs, J, Jung, Y, Mole, D, Lee, S, Torres-Cabala, C, Chung, Y, Merino, M, Trepel, J, Zbar, B, Toro, J, Ratcliffe, P, Linehan, WM, Neckers, L