Framework of the strengths and challenges of clinically integrated trials: an expert panel report by Peters, AE, Jones, WS, Anderson, B, Bramante, CT, Broedl, U, Hornik, CP, Kehoe, L, Knowlton, KU, Krofah, E, Landray, M, Locke, T, Patel, MR, Psotka, M, Rockhold, FW, Roessig, L, Rothman, RL, Schofield, L, Stockbridge, N, Trontell, A, Curtis, LH, Tenaerts, P, Hernandez, AF