A Chemo-Genomic Approach Identifies Diverse Epigenetic Therapeutic Vulnerabilities in MYCN-Amplified Neuroblastoma by Aleksandar Krstic, Anja Konietzny, Anja Konietzny, Melinda Halasz, Peter Cain, Peter Cain, Udo Oppermann, Udo Oppermann, Walter Kolch, Walter Kolch, David J. Duffy, David J. Duffy, David J. Duffy

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Recognition of Dimethylarginine Analogues by Tandem Tudor Domain Protein Spindlin1 by Miriam R. B. Porzberg, Laust Moesgaard, Catrine Johansson, Udo Oppermann, Jacob Kongsted, Jasmin Mecinović

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HSD3B1 is an oxysterol 3β-hydroxysteroid dehydrogenase in human placenta by Alison Dickson, Eylan Yutuc, Catherine A. Thornton, James E. Dunford, Udo Oppermann, Yuqin Wang, William J. Griffiths

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Divergent roles of prostacyclin and PGE2 in human tendinopathy by Filip Bergqvist, Andrew J. Carr, Kim Wheway, Bridget Watkins, Udo Oppermann, Per-Johan Jakobsson, Stephanie G. Dakin

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Linker Histone H1.2 Directs Genome-wide Chromatin Association of the Retinoblastoma Tumor Suppressor Protein and Facilitates Its Function by Shonagh Munro, Edward S. Hookway, Melanie Floderer, Simon M. Carr, Rebecca Konietzny, Benedikt M. Kessler, Udo Oppermann, Nicholas B. La Thangue

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KMT2A associates with PHF5A-PHF14-HMG20A-RAI1 subcomplex in pancreatic cancer stem cells and epigenetically regulates their characteristics by Mai Abdel Mouti, Siwei Deng, Martin Pook, Jessica Malzahn, Aniko Rendek, Stefania Militi, Reshma Nibhani, Zahir Soonawalla, Udo Oppermann, Chang-il Hwang, Siim Pauklin

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Structural basis for substrate specificity in human monomeric carbonyl reductases. by Ewa S Pilka, Frank H Niesen, Wen Hwa Lee, Yasser El-Hawari, James E Dunford, Grazyna Kochan, Vladimir Wsol, Hans-Joerg Martin, Edmund Maser, Udo Oppermann

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High-affinity inhibitors of human NAD-dependent 15-hydroxyprostaglandin dehydrogenase: mechanisms of inhibition and structure-activity relationships. by Frank H Niesen, Lena Schultz, Ajit Jadhav, Chitra Bhatia, Kunde Guo, David J Maloney, Ewa S Pilka, Minghua Wang, Udo Oppermann, Tom D Heightman, Anton Simeonov

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PB1808: EPIGENETIC INHIBITOR SCREEN TO IDENTIFY THERAPEUTIC CANDIDATES FOR MNX1-OVEREXPRESSING AML by Simge Kelekci, Anna Riedel, Dieter Weichenhan, Ashish Goyal, Katherine Kelly, Marion Baehr, Birgitta Michels, Cindy Koerner, Irene Orzella, James Dunford, Pavlo Lutsik, Stefan Wiemann, Udo Oppermann, Christoph Plass

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PRMT5 inhibition shows in vitro efficacy against H3K27M-altered diffuse midline glioma, but does not extend survival in vivo by Elizabeth J. Brown, Leire Balaguer-Lluna, Adam P. Cribbs, Martin Philpott, Leticia Campo, Molly Browne, Jong Fu Wong, Udo Oppermann, Ángel M. Carcaboso, Alex N. Bullock, Gillian Farnie

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Elucidating the path to Plasmodium prolyl-tRNA synthetase inhibitors that overcome halofuginone resistance by Mark A. Tye, N. Connor Payne, Catrine Johansson, Kritika Singh, Sofia A. Santos, Lọla Fagbami, Akansha Pant, Kayla Sylvester, Madeline R. Luth, Sofia Marques, Malcolm Whitman, Maria M. Mota, Elizabeth A. Winzeler, Amanda K. Lukens, Emily R. Derbyshire, Udo Oppermann, Dyann F. Wirth, Ralph Mazitschek

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The oncometabolite 2-hydroxyglutarate activates the mTOR signalling pathway by Mélissa Carbonneau, Laurence M. Gagné, Marie-Eve Lalonde, Marie-Anne Germain, Alena Motorina, Marie-Christine Guiot, Blandine Secco, Emma E. Vincent, Anthony Tumber, Laura Hulea, Jonathan Bergeman, Udo Oppermann, Russell G. Jones, Mathieu Laplante, Ivan Topisirovic, Kevin Petrecca, Marc-Étienne Huot, Frédérick A. Mallette

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Prospective Assessment of Tumour Burden and Bone Disease in Plasma Cell Dyscrasias Using DW-MRI and Exploratory Bone Biomarkers by Gaurav Agarwal, Guido Nador, Sherin Varghese, Hiwot Getu, Charlotte Palmer, Edmund Watson, Claudio Pereira, Germana Sallemi, Karen Partington, Neel Patel, Rajkumar Soundarajan, Rebecca Mills, Richard Brouwer, Marina Maritati, Aarti Shah, Delia Peppercorn, Udo Oppermann, Claire M. Edwards, Christopher T. Rodgers, Muhammad Kassim Javaid, Sarah Gooding, Karthik Ramasamy

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SSTR2 in Nasopharyngeal Carcinoma: Relationship with Latent EBV Infection and Potential as a Therapeutic Target by Oscar Emanuel, Jacklyn Liu, Volker H. Schartinger, Wen Long Nei, Yuk Yu Chan, Chi Man Tsang, Herbert Riechelmann, Liam Masterson, Johannes Haybaeck, Udo Oppermann, Stefan M. Willems, Marc L. Ooft, Guido Wollmann, David Howard, Bart Vanhaesebroeck, Valerie J. Lund, Gary Royle, Melvin L. K. Chua, Kwok Wai Lo, Pierre Busson, Matt Lechner

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Correction: Prolyl-tRNA synthetase as a novel therapeutic target in multiple myeloma by Keiji Kurata, Anna James-Bott, Mark A. Tye, Leona Yamamoto, Mehmet K. Samur, Yu-Tzu Tai, James Dunford, Catrine Johansson, Filiz Senbabaoglu, Martin Philpott, Charlotte Palmer, Karthik Ramasamy, Sarah Gooding, Mihaela Smilova, Giorgia Gaeta, Manman Guo, John C. Christianson, N. Connor Payne, Kritika Singh, Kubra Karagoz, Matthew E. Stokes, Maria Ortiz, Patrick Hagner, Anjan Thakurta, Adam Cribbs, Ralph Mazitschek, Teru Hideshima, Kenneth C. Anderson, Udo Oppermann

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Prolyl-tRNA synthetase as a novel therapeutic target in multiple myeloma by Keiji Kurata, Anna-James Bott, Mark A. Tye, Leona Yamamoto, Mehmet K. Samur, Yu-Tzu Tai, James Dunford, Catrine Johansson, Filiz Senbabaoglu, Martin Philpott, Charlotte Palmer, Karthik Ramasamy, Sarah Gooding, Mihaela Smilova, Giorgia Gaeta, Manman Guo, John C. Christianson, N. Connor Payne, Kritika Singh, Kubra Karagoz, Matthew E. Stokes, Maria Ortiz, Patrick Hagner, Anjan Thakurta, Adam Cribbs, Ralph Mazitschek, Teru Hideshima, Kenneth C. Anderson, Udo Oppermann

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Globally altered epigenetic landscape and delayed osteogenic differentiation in H3.3-G34W-mutant giant cell tumor of bone by Pavlo Lutsik, Annika Baude, Daniela Mancarella, Simin Öz, Alexander Kühn, Reka Toth, Joschka Hey, Umut H. Toprak, Jinyeong Lim, Viet Ha Nguyen, Chao Jiang, Anand Mayakonda, Mark Hartmann, Felix Rosemann, Kersten Breuer, Dominik Vonficht, Florian Grünschläger, Suman Lee, Maren Kirstin Schuhmacher, Denis Kusevic, Anna Jauch, Dieter Weichenhan, Jozef Zustin, Matthias Schlesner, Simon Haas, Joo Hyun Park, Yoon Jung Park, Udo Oppermann, Albert Jeltsch, Florian Haller, Jörg Fellenberg, Anders M. Lindroth, Christoph Plass

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Somatostatin receptor 2 expression in nasopharyngeal cancer is induced by Epstein Barr virus infection: impact on prognosis, imaging and therapy by Matt Lechner, Volker H. Schartinger, Christopher D. Steele, Wen Long Nei, Marc Lucas Ooft, Liesa-Marie Schreiber, Christodoulos P. Pipinikas, Grace Tin-Yun Chung, Yuk Yu Chan, Feng Wu, Ka-Fai To, Chi Man Tsang, Wayne Pearce, Daniele Morelli, Martin Philpott, Liam Masterson, Reshma Nibhani, Graham Wells, Christopher G. Bell, Julia Koller, Susanne Delecluse, Yim Ling Yip, Jacklyn Liu, Cillian T. Forde, Martin D. Forster, Amrita Jay, József Dudás, Annika Krapp, Simon Wan, Christian Uprimny, Susanne Sprung, Johannes Haybaeck, Tim R. Fenton, Kerry Chester, Christina Thirlwell, Gary Royle, Teresa Marafioti, Rajeev Gupta, Sagung Rai Indrasari, Camelia Herdini, Mohd Afiq Mohd Slim, I. Indrawati, Liam Sutton, Renske Fles, Bing Tan, Joe Yeong, Amit Jain, Shuting Han, Haitao Wang, Kelvin S. H. Loke, Wan He, Ruilian Xu, Hongtao Jin, Zhiqiang Cheng, David Howard, Peter H. Hwang, Quynh-Thu Le, Joshua K. Tay, Robert B. West, Sai Wah Tsao, Tim Meyer, Herbert Riechelmann, Udo Oppermann, Henri-Jacques Delecluse, Stefan M. Willems, Melvin L. K. Chua, Pierre Busson, Kwok Wai Lo, Guido Wollmann, Nischalan Pillay, Bart Vanhaesebroeck, Valerie J. Lund

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