Rationally Designed Variants of α-Synuclein Illuminate Its in vivo Structural Properties in Health and Disease by Ulf Dettmer

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α-Synuclein serine129 phosphorylation – the physiology of pathology by Nagendran Ramalingam, Ulf Dettmer

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Lipotoxicity Downstream of α-Synuclein Imbalance: A Relevant Pathomechanism in Synucleinopathies? by Arati Tripathi, Saranna Fanning, Ulf Dettmer

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Astrocytes in Parkinson’s Disease: From Role to Possible Intervention by Tianyou Wang, Yingqi Sun, Ulf Dettmer

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A new method for quantitative immunoblotting of endogenous α-synuclein. by Andrew J Newman, Dennis Selkoe, Ulf Dettmer

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Dynamic behaviors of α-synuclein and tau in the cellular context: New mechanistic insights and therapeutic opportunities in neurodegeneration by Fred Yeboah, Tae-Eun Kim, Anke Bill, Ulf Dettmer

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Discovery of 4-aminoindole carboxamide derivatives to curtail alpha-synuclein and tau isoform 2N4R oligomer formation by Eduardo Ramirez, Sehong Min, Susantha K. Ganegamage, Kazuma Shimanaka, Magaly Guzman Sosa, Ulf Dettmer, Jean-Christophe Rochet, Jessica S. Fortin

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Parkinson-causing mutations in LRRK2 impair the physiological tetramerization of endogenous α-synuclein in human neurons by Luis Fonseca-Ornelas, Jonathan M. S. Stricker, Stephanie Soriano-Cruz, Beatrice Weykopf, Ulf Dettmer, Christina R. Muratore, Clemens R. Scherzer, Dennis J. Selkoe

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1,4-Diurea- and 1,4-Dithiourea-Substituted Aromatic Derivatives Selectively Inhibit α‑Synuclein Oligomer Formation In Vitro by Susantha K. Ganegamage, Eduardo Ramirez, Heba Alnakhala, Arati Tripathi, Cuong Calvin Duc Nguyen, Ashique Zami, Raluca Ostafe, Shiliang Tian, Ulf Dettmer, Jessica S. Fortin

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Rapid Alpha-Synuclein Toxicity in a Neural Cell Model and Its Rescue by a Stearoyl-CoA Desaturase Inhibitor by Elizabeth Terry-Kantor, Arati Tripathi, Thibaut Imberdis, Zachary M. LaVoie, Gary P. H. Ho, Dennis Selkoe, Saranna Fanning, Nagendran Ramalingam, Ulf Dettmer

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Generation of G51D and 3D mice reveals decreased α-synuclein tetramer-monomer ratios promote Parkinson’s disease phenotypes by Silke Nuber, Xiaoqun Zhang, Thomas D. McCaffery, Tim E. Moors, Marie-Alexandre Adom, Wolf N. Hahn, Dylan Martin, Maria Ericsson, Arati Tripathi, Ulf Dettmer, Per Svenningsson, Dennis J. Selkoe

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Author Correction: Generation of G51D and 3D mice reveals decreased α-synuclein tetramer-monomer ratios promote Parkinson’s disease phenotypes by Silke Nuber, Xiaoqun Zhang, Thomas D. McCaffery, Tim E. Moors, Marie-Alexandre Adom, Wolf N. Hahn, Dylan Martin, Maria Ericsson, Arati Tripathi, Ulf Dettmer, Per Svenningsson, Dennis J. Selkoe

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Nortriptyline inhibits aggregation and neurotoxicity of alpha-synuclein by enhancing reconfiguration of the monomeric form by Timothy J. Collier, Kinshuk R. Srivastava, Craig Justman, Tom Grammatopoulous, Birgit Hutter-Paier, Manuela Prokesch, Daniel Havas, Jean-Christophe Rochet, Fang Liu, Kevin Jock, Patrícia de Oliveira, Georgia L. Stirtz, Ulf Dettmer, Caryl E. Sortwell, Mel B. Feany, Peter Lansbury, Lisa Lapidus, Katrina L. Paumier

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Lipase regulation of cellular fatty acid homeostasis as a Parkinson’s disease therapeutic strategy by Saranna Fanning, Haley Cirka, Jennifer L. Thies, Jooyoung Jeong, Sarah M. Niemi, Joon Yoon, Gary P. H. Ho, Julian A. Pacheco, Ulf Dettmer, Lei Liu, Clary B. Clish, Kevin J. Hodgetts, John N. Hutchinson, Christina R. Muratore, Guy A. Caldwell, Kim A. Caldwell, Dennis Selkoe

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Dynamic physiological α-synuclein S129 phosphorylation is driven by neuronal activity by Nagendran Ramalingam, Shan-Xue Jin, Tim E. Moors, Luis Fonseca-Ornelas, Kazuma Shimanaka, Shi Lei, Hugh P. Cam, Aurelia Hays Watson, Lisa Brontesi, Lai Ding, Dinc Yasat Hacibaloglu, Haiyang Jiang, Se Joon Choi, Ellen Kanter, Lei Liu, Tim Bartels, Silke Nuber, David Sulzer, Eugene V. Mosharov, Weisheng V. Chen, Shaomin Li, Dennis J. Selkoe, Ulf Dettmer

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