Is the Obesity Paradox in Type 2 Diabetes Due to Artefacts of Biases? An Analysis of Pooled Cohort Data from the Heinz Nixdorf Recall Study and the Study of Health in Pomerania by Kowall B, Stang A, Erbel R, Moebus S, Petersmann A, Steveling A, Jöckel KH, Völzke H

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Genome-wide association scan identifies a colorectal cancer susceptibility locus on 11q23 and replicates risk loci at 8q24 and 18q21. by Tenesa, A, Farrington, S, Prendergast, J, Porteous, M, Walker, M, Haq, N, Barnetson, R, Theodoratou, E, Cetnarskyj, R, Cartwright, N, Semple, C, Clark, A, Reid, F, Smith, L, Kavoussanakis, K, Koessler, T, Pharoah, P, Buch, S, Schafmayer, C, Tepel, J, Schreiber, S, Völzke, H, Schmidt, C, Hampe, J, Chang-Claude, J

Insights from a methylome-wide association study of antidepressant exposure by Davyson, E, Shen, X, Huider, F, Adams, MJ, Borges, K, McCartney, DL, Barker, LF, van Dongen, J, Boomsma, DI, Weihs, A, Grabe, HJ, Kühn, L, Teumer, A, Völzke, H, Zhu, T, Kaprio, J, Ollikainen, M, David, FS, Meinert, S, Stein, F, Forstner, AJ, Dannlowski, U, Kircher, T, Tapuc, A, Wray, NR

Cumulative impact of common genetic variants and other risk factors on colorectal cancer risk in 42,103 individuals. by Dunlop, MG, Tenesa, A, Farrington, S, Ballereau, S, Brewster, D, Koessler, T, Pharoah, P, Schafmayer, C, Hampe, J, Völzke, H, Chang-Claude, J, Hoffmeister, M, Brenner, H, von Holst, S, Picelli, S, Lindblom, A, Jenkins, M, Hopper, J, Casey, G, Duggan, D, Newcomb, P, Abulí, A, Bessa, X, Ruiz-Ponte, C, Castellví-Bel, S

Cumulative impact of common genetic variants and other risk factors on colorectal cancer risk in 42 103 individuals by Dunlop, MG, Tenesa, A, Farrington, S, Ballereau, S, Brewster, D, Koessler, T, Pharoah, P, Schafmayer, C, Hampe, J, Völzke, H, Chang-Claude, J, Hoffmeister, M, Brenner, H, Von Holst, S, Picelli, S, Lindblom, A, Jenkins, M, Hopper, J, Casey, G, Duggan, D, Newcomb, P, Abulí, A, Bessa, X, Ruiz-Ponte, C, Castellví-Bel, S

Rare genomic structural variants in complex disease: lessons from the replication of associations with obesity by Walters, R, Coin, L, Ruokonen, A, De Smith, A, El-Sayed Moustafa, J, Jacquemont, S, Elliott, P, Esko, T, Hartikainen, A, Laitinen, J, Männik, K, Martinet, D, Meyre, D, Nauck, M, Schurmann, C, Sladek, R, Thorleifsson, G, Thorsteinsdóttir, U, Valsesia, A, Waeber, G, Zufferey, F, Balkau, B, Pattou, F, Metspalu, A, Völzke, H, Vollenweider, P, Stefansson, K, Järvelin, MR, Beckmann, J, Froguel, P, Blakemore, A

Meta-analysis of mismatch repair polymorphisms within the cogent consortium for colorectal cancer susceptibility by Picelli, S, Lorenzo Bermejo, J, Chang-Claude, J, Hoffmeister, M, Fernández-Rozadilla, C, Carracedo, A, Castells, A, Castellví-Bel, S, Naccarati, A, Pardini, B, Vodickova, L, Müller, H, Talseth-Palmer, B, Stibbard, G, Peterlongo, P, Nici, C, Veneroni, S, Li, L, Casey, G, Tenesa, A, Farrington, S, Tomlinson, I, Moreno, V, Van Wezel, T, Wijnen, J, Dunlop, M, Radice, P, Scott, R, Vodicka, P, Ruiz-Ponte, C, Brenner, H, Buch, S, Völzke, H, Hampe, J, Schafmayer, C, Lindblom, A

Subcortical brain structure and suicidal behaviour in major depressive disorder: a meta-analysis from the ENIGMA-MDD working group by Rentería, ME, Schmaal, L, Hibar, DP, Couvy-Duchesne, B, Strike, LT, Mills, NT, de Zubicaray, GI, McMahon, KL, Medland, SE, Gillespie, NA, Hatton, SN, Lagopoulos, J, Veltman, DJ, van der Wee, N, van Erp, TGM, Wittfeld, K, Grabe, HJ, Block, A, Hegenscheid, K, Völzke, H, Veer, IM, Walter, H, Schnell, K, Schramm, E, Normann, C, Schoepf, D, Konrad, C, Zurowski, B, Godlewska, BR, Cowen, PJ, Penninx, BWJH, Jahanshad, N, Thompson, PM, Wright, MJ, Martin, NG, Christensen, H, Hickie, IB

Eight common genetic variants associated with serum DHEAS levels suggest a key role in ageing mechanisms. by Zhai, G, Teumer, A, Stolk, L, Perry, JR, Vandenput, L, Coviello, A, Koster, A, Bell, J, Bhasin, S, Eriksson, J, Eriksson, A, Ernst, F, Ferrucci, L, Frayling, T, Glass, D, Grundberg, E, Haring, R, Hedman, A, Hofman, A, Kiel, D, Kroemer, H, Liu, Y, Lunetta, K, Maggio, M, Lorentzon, M, Mangino, M, Melzer, D, Miljkovic, I, Nica, A, Penninx, B, Vasan, R, Rivadeneira, F, Small, K, Soranzo, N, Uitterlinden, A, Völzke, H, Wilson, S, Xi, L, Zhuang, W, Harris, T, Murabito, J, Ohlsson, C, Murray, A, de Jong, F, Spector, T, Wallaschofski, H, Perry, J

Higher thyrotropin leads to unfavorable lipid profile and somewhat higher cardiovascular disease risk: evidence from multi-cohort Mendelian randomization and metabolomic profiling. by van Vliet, NA, Bos, MM, Thesing, CS, Chaker, L, Pietzner, M, Houtman, E, Neville, MJ, Li-Gao, R, Trompet, S, Mustafa, R, Ahmadizar, F, Beekman, M, Bot, M, Budde, K, Christodoulides, C, Dehghan, A, Delles, C, Elliott, P, Evangelou, M, Gao, H, Ghanbari, M, van Herwaarden, AE, Ikram, MA, Jaeger, M, Jukema, JW, Karaman, I, Karpe, F, Kloppenburg, M, Meessen, JMTA, Meulenbelt, I, Milaneschi, Y, Mooijaart, SP, Mook-Kanamori, DO, Netea, MG, Netea-Maier, RT, Peeters, RP, Penninx, BWJH, Sattar, N, Slagboom, PE, Suchiman, HED, Völzke, H, Willems van Dijk, K, Noordam, R, van Heemst, D

Use of repeated blood pressure and cholesterol measurements to improve cardiovascular disease risk prediction: An individual-participant-data meta-analysis by Paige, E, Barrett, J, Pennells, L, Sweeting, M, Willeit, P, Di Angelantonio, E, Gudnason, V, Nordestgaard, BG, Psaty, BM, Goldbourt, U, Best, LG, Assmann, G, Salonen, JT, Nietert, PJ, Verschuren, WMM, Brunner, EJ, Kronmal, RA, Salomaa, V, Bakker, SJL, Dagenais, GR, Sato, S, Jansson, J-H, Willeit, J, Onat, A, de la Cámara, AG, Roussel, R, Völzke, H, Dankner, R, Tipping, RW, Meade, TW, Donfrancesco, C, Kuller, LH, Peters, A, Gallacher, J, Kromhout, D, Iso, H, Knuiman, M, Casiglia, E, Kavousi, M, Palmieri, L, Sundström, J, Davis, BR, Njølstad, I, Couper, D, Danesh, J, Thompson, SG, Wood, A

Meta-analysis of 28,141 individuals identifies common variants within five new loci that influence uric acid concentrations. by Kolz, M, Johnson, T, Sanna, S, Teumer, A, Vitart, V, Perola, M, Mangino, M, Albrecht, E, Wallace, C, Farrall, M, Johansson, A, Nyholt, DR, Aulchenko, Y, Beckmann, J, Bergmann, S, Bochud, M, Brown, M, Campbell, H, Connell, J, Dominiczak, A, Homuth, G, Lamina, C, McCarthy, M, Meitinger, T, Mooser, V, Munroe, P, Nauck, M, Peden, J, Prokisch, H, Salo, P, Salomaa, V, Samani, N, Schlessinger, D, Uda, M, Volker, U, Waeber, G, Waterworth, D, Wang-Sattler, R, Wright, A, Adamski, J, Whitfield, J, Gyllensten, U, Wilson, J, Rudan, I, Pramstaller, P, Watkins, H, Doering, A, Wichmann, H, Spector, T, Peltonen, L, Volzke, H, Nagaraja, R, Vollenweider, P, Caulfield, M, Illig, T, Gieger, C

Genetic determinants of serum testosterone concentrations in men. by Ohlsson, C, Wallaschofski, H, Lunetta, K, Stolk, L, Perry, JR, Koster, A, Petersen, A, Eriksson, J, Lehtimäki, T, Huhtaniemi, I, Hammond, G, Maggio, M, Coviello, A, Ferrucci, L, Heier, M, Hofman, A, Holliday, K, Jansson, J, Kähönen, M, Karasik, D, Karlsson, M, Kiel, D, Liu, Y, Ljunggren, O, Lorentzon, M, Lyytikäinen, L, Meitinger, T, Mellström, D, Melzer, D, Miljkovic, I, Nauck, M, Nilsson, M, Penninx, B, Pye, SR, Vasan, R, Reincke, M, Rivadeneira, F, Tajar, A, Teumer, A, Uitterlinden, A, Ulloor, J, Viikari, J, Völker, U, Völzke, H, Wichmann, H, Wu, T, Zhuang, W, Ziv, E, Wu, F, Raitakari, O, Eriksson, A, Bidlingmaier, M, Harris, T, Murray, A, de Jong, F, Murabito, J, Bhasin, S, Vandenput, L, Haring, R

Meta-Analysis of the INSIG2 Association with Obesity Including 74,345 Individuals: Does Heterogeneity of Estimates Relate to Study Design? by Heid, I, Huth, C, Loos, R, Kronenberg, F, Adamkova, V, Anand, S, Ardlie, K, Biebermann, H, Bjerregaard, P, Boeing, H, Bouchard, C, Ciullo, M, Cooper, J, Corella, D, Dina, C, Engert, J, Fisher, E, Francès, F, Froguel, P, Hebebrand, J, Hegele, R, Hinney, A, Hoehe, MR, Hu, F, Hubacek, J, Humphries, SE, Hunt, S, Illig, T, Järvelin, MR, Kaakinen, M, Kollerits, B, Krude, H, Kumar, J, Lange, L, Langer, B, Li, S, Luchner, A, Lyon, H, Meyre, D, Mohlke, K, Mooser, V, Nebel, A, Nguyen, T, Paulweber, B, Perusse, L, Qi, L, Rankinen, T, Rosskopf, D, Schreiber, S, Sengupta, S, Sorice, R, Suk, A, Thorleifsson, G, Thorsteinsdottir, U, Völzke, H, Vimaleswaran, K, Wareham, N, Waterworth, D, Yusuf, S, Lindgren, C, McCarthy, M, Lange, C, Hirschhorn, J, Laird, N, Wichmann, H

Multiethnic genome-wide meta-analysis of ectopic fat depots identifies loci associated with adipocyte development and differentiation by Chu, A, Deng, X, Fisher, V, Drong, A, Zhang, Y, Feitosa, M, Liu, C, Weeks, O, Choh, A, Duan, Q, Dyer, T, Eicher, J, Guo, X, Heard-Costa, N, Kacprowski, T, Kent, J, Lange, L, Liu, X, Lohman, K, Lu, L, Mahajan, A, O'Connell, J, Parihar, A, Peralta, J, Smith, A, Zhang, Y, Homuth, G, Kissebah, A, Kullberg, J, Laqua, R, Launer, L, Nauck, M, Olivier, M, Peyser, P, Terry, J, Wojczynski, M, Yao, J, Bielak, L, Blangero, J, Borecki, I, Bowden, D, Carr, J, Czerwinski, S, Ding, J, Friedrich, N, Gudnason, V, Harris, T, Ingelsson, E, Johnson, A, Kardia, S, Langefeld, C, Lind, L, Liu, Y, Mitchell, B, Morris, A, Mosley, T, Rotter, J, Shuldiner, A, Towne, B, Völzke, H, Wallaschofski, H, Wilson, J, Allison, M, Lindgren, C, Goessling, W, Cupples, L, Steinhauser, M, Fox, C

Genome-wide association study of blood pressure extremes identifies variant near UMOD associated with hypertension. by Padmanabhan, S, Melander, O, Johnson, T, Di Blasio, A, Lee, W, Gentilini, D, Hastie, C, Menni, C, Monti, M, Delles, C, Laing, S, Corso, B, Navis, G, Kwakernaak, A, van der Harst, P, Bochud, M, Maillard, M, Burnier, M, Hedner, T, Kjeldsen, S, Wahlstrand, B, Sjogren, M, Fava, C, Montagnana, M, Danese, E, Torffvit, O, Hedblad, B, Snieder, H, Connell, J, Brown, M, Samani, N, Farrall, M, Cesana, G, Mancia, G, Signorini, S, Grassi, G, Eyheramendy, S, Wichmann, H, Laan, M, Strachan, D, Sever, P, Shields, D, Stanton, A, Vollenweider, P, Teumer, A, Volzke, H, Rettig, R, Newton-Cheh, C, Arora, P, Zhang, F, Soranzo, N, Spector, T, Lucas, G, Kathiresan, S, Siscovick, D, Luan, J, Loos, R, Wareham, N, Penninx, B, Nolte, I, McBride, M, Miller, W, Nicklin, SA, Baker, A, Graham, D, McDonald, R, Pell, J, Sattar, N, Welsh, P, Munroe, P, Caulfield, M, Zanchetti, A, Dominiczak, A

Cardiovascular risk factors associated with venous thromboembolism by Gregson, J, Kaptoge, S, Bolton, T, Pennells, L, Willeit, P, Burgess, S, Bell, S, Sweeting, M, Rimm, EB, Kabrhel, C, Zöller, B, Assmann, G, Gudnason, V, Folsom, AR, Arndt, V, Fletcher, A, Norman, PE, Nordestgaard, BG, Kitamura, A, Mahmoodi, BK, Whincup, PH, Knuiman, M, Salomaa, V, Meisinger, C, Koenig, W, Kavousi, M, Völzke, H, Cooper, JA, Ninomiya, T, Casiglia, E, Rodriguez, B, Ben-Shlomo, Y, Després, J-P, Simons, L, Barrett-Connor, E, Björkelund, C, Notdurfter, M, Kromhout, D, Price, J, Sutherland, SE, Sundström, J, Kauhanen, J, Gallacher, J, Beulens, JWJ, Dankner, R, Cooper, C, Giampaoli, S, Deen, JF, De La Cámara, A, Kuller, LH, Rosengren, A, Svensson, PJ, Nagel, D, Crespo, CJ, Brenner, H, Albertorio-Diaz, JR, Atkins, R, Brunner, EJ, Shipley, M, Njølstad, I, Lawlor, DA, Van Der Schouw, YT, Selmer, RM, Trevisan, M, Verschuren, WMM, Greenland, P, Wassertheil-Smoller, S, Lowe, GDO, Wood, AM, Butterworth, AS, Thompson, SG, Danesh, J, Di Angelantonio, E, Meade, T, Emerging Risk Factors Collaboration

Genome-wide joint meta-analysis of SNP and SNP-by-smoking interaction identifies novel loci for pulmonary function by Hancock, D, Artigas, MS, Gharib, SA, Henry, A, Manichaikul, A, Ramasamy, A, Loth, D, Imboden, M, Koch, B, McArdle, W, Smith, A, Smolonska, J, Sood, A, Tang, W, Wilk, J, Zhai, G, Zhao, J, Aschard, H, Burkart, K, Curjuric, I, Eijgelsheim, M, Elliott, P, Gu, X, Harris, T, Janson, C, Homuth, G, Hysi, P, Liu, J, Loehr, L, Lohman, K, Loos, R, Manning, A, Marciante, K, Obeidat, M, Postma, D, Aldrich, M, Brusselle, G, Chen, T, Eiriksdottir, G, Franceschini, N, Heinrich, J, Rotter, J, Wijmenga, C, Williams, O, Bentley, A, Hofman, A, Laurie, C, Lumley, T, Morrison, A, Joubert, B, Rivadeneira, F, Couper, D, Kritchevsky, S, Liu, Y, Wjst, M, Wain, L, Vonk, J, Uitterlinden, A, Rochat, T, Rich, S, Psaty, B, O'Connor, G, North, K, Mirel, D, Meibohm, B, Launer, L, Khaw, K, Hartikainen, A, Hammond, C, Gläser, S, Marchini, J, Kraft, P, Wareham, N, Völzke, H, Stricker, B, Spector, T, Probst-Hensch, N, Jarvis, D, Jarvelin, MR, Heckbert, SR, Gudnason, V, Boezen, H, Barr, R, Cassano, P, Strachan, D, Fornage, M, Hall, I, Dupuis, J, Tobin, MD, London, S

No evidence for genome-wide interactions on plasma fibrinogen by smoking, alcohol consumption and body mass index: results from meta-analyses of 80,607 subjects by Baumert, J, Huang, J, McKnight, B, Sabater-Lleal, M, Steri, M, Chu, A, Trompet, S, Lopez, L, Fornage, M, Teumer, A, Tang, W, Rudnicka, A, Mälarstig, A, Hottenga, J, Kavousi, M, Lahti, J, Tanaka, T, Hayward, C, Huffman, J, Morange, P, Rose, L, Basu, S, Rumley, A, Stott, D, Buckley, B, De Craen, A, Sanna, S, Masala, M, Biffar, R, Homuth, G, Silveira, A, Sennblad, B, Goel, A, Watkins, H, Müller-Nurasyid, M, Rückerl, R, Taylor, K, Chen, M, De Geus, E, Hofman, A, Witteman, J, Maat, D, Palotie, A, Davies, G, Siscovick, D, Kolcic, I, Wild, S, Song, J, McArdle, W, Ford, I, Sattar, N, Schlessinger, D, Grotevendt, A, Franzosi, MG, Illig, T, Waldenberger, M, Lumley, T, Tofler, G, Willemsen, G, Uitterlinden, A, Rivadeneira, F, Räikkönen, K, Chasman, D, Folsom, A, Lowe, G, Westendorp, R, Slagboom, P, Cucca, F, Wallaschofski, H, Strawbridge, R, Seedorf, U, Koenig, W, Bis, J, Mukamal, K, Van Dongen, J, Widen, E, Franco, O, Starr, J, Liu, K, Ferrucci, L, Polasek, O, Wilson, J, Oudot-Mellakh, T, Campbell, H, Navarro, P, Bandinelli, S, Eriksson, J, Boomsma, D, Dehghan, A, Clarke, R, Hamsten, A, Boerwinkle, E, Jukema, J, Naitza, S, Ridker, P, Völzke, H, Deary, I, Reiner, A, Trégouët, D, O'Donnell, C, Strachan, D, Peters, A, Smith, N

Genome-wide association study in 79,366 European-ancestry individuals informs the genetic architecture of 25-hydroxyvitamin D levels. by Jiang, X, O'Reilly, PF, Aschard, H, Hsu, Y-H, Richards, JB, Dupuis, J, Ingelsson, E, Karasik, D, Pilz, S, Berry, D, Kestenbaum, B, Zheng, J, Luan, J, Sofianopoulou, E, Streeten, EA, Albanes, D, Lutsey, PL, Yao, L, Tang, W, Econs, MJ, Wallaschofski, H, Völzke, H, Zhou, A, Power, C, McCarthy, MI, Michos, ED, Boerwinkle, E, Weinstein, SJ, Freedman, ND, Huang, W-Y, Van Schoor, NM, van der Velde, N, Groot, LCPGMD, Booth, SL, Vasan, RS, Liu, C-T, Zhou, Y, Ripatti, S, Ohlsson, C, Eriksson, JG, Shea, MK, Houston, DK, Kritchevsky, SB, Liu, Y, Lohman, KK, Ferrucci, L, Peacock, M, Gieger, C, Beekman, M, Slagboom, E, Deelen, J, Heemst, DV, Kleber, ME, März, W, de Boer, IH, Wood, AC, Rotter, JI, Rich, SS, Robinson-Cohen, C, Heijer, M, Jarvelin, M-R, Cavadino, A, Joshi, PK, Wilson, JF, Hayward, C, Lind, L, Michaëlsson, K, Trompet, S, Zillikens, MC, Uitterlinden, AG, Rivadeneira, F, Broer, L, Zgaga, L, Campbell, H, Theodoratou, E, Farrington, SM, Timofeeva, M, Dunlop, MG, Valdes, AM, Tikkanen, E, Lehtimäki, T, Lyytikäinen, L-P, Kähönen, M, Raitakari, OT, Mikkilä, V, Ikram, MA, Sattar, N, Jukema, JW, Wareham, NJ, Langenberg, C, Forouhi, NG, Gundersen, TE, Khaw, K-T, Butterworth, AS, Danesh, J, Spector, T, Wang, TJ, Hyppönen, E, Kraft, P, Kiel, DP