PI-05: PHARMACODYNAMIC EFFECTS OF AG-946, A HIGHLY POTENT NOVEL ACTIVATOR OF PYRUVATE KINASE, IN EX VIVO TREATMENT OF RED BLOOD CELLS FROM SICKLE CELL DISEASE PATIENTS by RAB M., VAN DIJK M., BOS J., VAN OIRSCHOT B., GERRITS J., KOSINSKI P., KUNG C., JANS J., VAN BEERS E., DANG L., VAN WIJK R.

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PI-02: FOLLOW-UP RESULTS OF A PHASE 2 STUDY ASSESSING THE SAFETY AND EFFICACY OF MITAPIVAT TREATMENT, AN ORAL PYRUVATE KINASE ACTIVATOR, FOR UP TO 60 WEEKS IN SUBJECTS WITH SICKLE... by VAN DIJK M., RAB M., VAN OIRSCHOT B., BOS J., DERICHS C., RIJNEVELD A., CNOSSEN M., NUR E., BIEMOND B., BARTELS M., JANS J., VAN SOLINGE W., SCHUTGENS R., VAN WIJK R., VAN BEERS E.

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P-032: INTEGRATIVE DIAGNOSIS OF SICKLE CELL DISEASE PATIENTS FOR PERSONALIZED MEDICINE by IDRIZOVIC A., COLLADO GIMBERT A., VAN BEERS E., COLOMBATTI R., BARTOLUCCI P., DE MONTALEMBERT M., BOARO M., BENEITEZ D., ORTUÑO A., RUIZ A., ISOLA I., CELA E., VAN WIJK R., RAB M., MAÑU PEREIRA M.

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P-023: 2,3-DIPHOSPHOGLYCERATE DETECTION VIA DIRECT INFUSION HIGH RESOLUTION MASS SPECTROMETRY CORRELATES WITH QUANTITATIVE DETECTION IN BLOOD OF PATIENTS WITH SICKLE CELL DISEASE by VAN DER VEEN S., VAN DIJK M., JANS J., VERHOEVEN-DUIF N., VAN WIJK R., BARTELS M., MAÑÚ PEREIRA M., COLOMBATTI R., MARTELLA M., MUNARETO V., BOARO M., BARTOLLUCI P., CNOSSEN M., BIEMOND B., VAN BEERS E.

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PI-04: OXYGEN GRADIENT EKTACYTOMETRY-DERIVED BIOMARKERS ARE ASSOCIATED WITH THE OCCURRENCE OF ACUTE COMPLICATIONS IN SICKLE CELL DISEASE by RAB M., KANNE C., BOISSON C., BOS J., VAN OIRSCHOT B., HOUWING M., RENOUX C., SCHUTGENS R., BARTELS M., RIJNEVELD A., NUR E., CNOSSEN M., PHILIPPE J., FORT R., CONNES P., VAN WIJK R., SHEEHAN V., VAN BEERS E.

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