Editorial: The Challenge of New Therapeutic Approaches for Unmet Therapeutic Needs by Arianna Carolina Rosa, Mitsunobu Mio, Ioanna Andreadou, Vadim V. Sumbayev

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Editorial: Pathological reactions of cytotoxic lymphoid cells as universal therapeutic targets in cancer and autoimmune disease by Vadim V. Sumbayev, Bernhard F. Gibbs, Elizaveta Fasler-Kan, Elizaveta Fasler-Kan

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IgE-dependent human basophil responses are inversely associated with the sarcoplasmic reticulum Ca2+-ATPase (SERCA) by Anette T. Hansen Selnø, Vadim V. Sumbayev, Bernhard F. Gibbs, Bernhard F. Gibbs

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Mitochondrial Defunctionalization Supresses Tim-3-Galectin-9 Secretory Pathway in Human Colorectal Cancer Cells and Thus Can Possibly Affect Tumor Immune Escape by Svetlana S. Sakhnevych, Inna M. Yasinska, Elizaveta Fasler-Kan, Elizaveta Fasler-Kan, Vadim V. Sumbayev

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Involvement of hypoxia-inducible factor-1 in the inflammatory responses of human LAD2 mast cells and basophils. by Vadim V Sumbayev, Inna Yasinska, Abraham E Oniku, Claire L Streatfield, Bernhard F Gibbs

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Differential Role of Hypoxia-Inducible Factor 1 Alpha in Toll-Like Receptor-Mediated and Allergic Inflammatory Reactions by Vadim V. Sumbayev, PhD, Sally A. Nicholas, PhD, Bernhard F. Gibbs, PhD

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Targeting of Basophil and Mast Cell Pro-Allergic Reactivity Using Functionalised Gold Nanoparticles by Inna M. Yasinska, Luigi Calzolai, Ulrike Raap, Rohanah Hussain, Giuliano Siligardi, Vadim V. Sumbayev, Bernhard F. Gibbs, Bernhard F. Gibbs

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Activation of immune evasion machinery is a part of the process of malignant transformation of human cells by Maryam Abooali, Inna M. Yasinska, Stephanie Schlichtner, Sabrina Ruggiero, Steffen M. Berger, Dietmar Cholewa, Milan Milošević, Andreas Bartenstein, Elizaveta Fasler-Kan, Vadim V. Sumbayev

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T lymphocytes induce human cancer cells derived from solid malignant tumors to secrete galectin-9 which facilitates immunosuppression in cooperation with other immune checkpoint pr... by Stephanie Schlichtner, Inna M Yasinska, Gurprit S Lall, Steffen M Berger, Sabrina Ruggiero, Dietmar Cholewa, Nijas Aliu, Bernhard F Gibbs, Elizaveta Fasler-Kan, Vadim V Sumbayev

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L-Kynurenine participates in cancer immune evasion by downregulating hypoxic signaling in T lymphocytes by Stephanie Schlichtner, Inna M. Yasinska, Elena Klenova, Maryam Abooali, Gurprit S. Lall, Steffen M. Berger, Sabrina Ruggiero, Dietmar Cholewa, Milan Milošević, Bernhard F. Gibbs, Elizaveta Fasler-Kan, Vadim V. Sumbayev

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High mobility group box 1 (HMGB1) acts as an “alarmin” to promote acute myeloid leukaemia progression by Inna M. Yasinska, Isabel Gonçalves Silva, Svetlana S. Sakhnevych, Laura Ruegg, Rohanah Hussain, Giuliano Siligardi, Walter Fiedler, Jasmin Wellbrock, Marco Bardelli, Luca Varani, Ulrike Raap, Steffen Berger, Bernhard F. Gibbs, Elizaveta Fasler-Kan, Vadim V. Sumbayev

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Macrophage Differentiation and Polarization Regulate the Release of the Immune Checkpoint Protein V-Domain Ig Suppressor of T Cell Activation by Gaetan Aime Noubissi Nzeteu, Gaetan Aime Noubissi Nzeteu, Stephanie Schlichtner, Sulamith David, Aylin Ruppenstein, Elizaveta Fasler-Kan, Elizaveta Fasler-Kan, Ulrike Raap, Ulrike Raap, Vadim V. Sumbayev, Bernhard F. Gibbs, N. Helge Meyer, N. Helge Meyer

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The Tim-3-galectin-9 Secretory Pathway is Involved in the Immune Escape of Human Acute Myeloid Leukemia Cells by Isabel Gonçalves Silva, Inna M. Yasinska, Svetlana S. Sakhnevych, Walter Fiedler, Jasmin Wellbrock, Marco Bardelli, Luca Varani, Rohanah Hussain, Giuliano Siligardi, Giacomo Ceccone, Steffen M. Berger, Yuri A. Ushkaryov, Bernhard F. Gibbs, Elizaveta Fasler-Kan, Vadim V. Sumbayev

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High Mobility Group Box 1 (HMGB1) Induces Toll-Like Receptor 4-Mediated Production of the Immunosuppressive Protein Galectin-9 in Human Cancer Cells by Anette Teo Hansen Selnø, Stephanie Schlichtner, Inna M. Yasinska, Svetlana S. Sakhnevych, Walter Fiedler, Jasmin Wellbrock, Steffen M. Berger, Steffen M. Berger, Elena Klenova, Bernhard F. Gibbs, Bernhard F. Gibbs, Elizaveta Fasler-Kan, Elizaveta Fasler-Kan, Vadim V. Sumbayev

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Ligand-Receptor Interactions of Galectin-9 and VISTA Suppress Human T Lymphocyte Cytotoxic Activity by Inna M. Yasinska, N. Helge Meyer, Stephanie Schlichtner, Rohanah Hussain, Giuliano Siligardi, Maxwell Casely-Hayford, Walter Fiedler, Jasmin Wellbrock, Cloe Desmet, Luigi Calzolai, Luca Varani, Steffen M. Berger, Ulrike Raap, Bernhard F. Gibbs, Bernhard F. Gibbs, Elizaveta Fasler-Kan, Elizaveta Fasler-Kan, Vadim V. Sumbayev

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The Tim-3-Galectin-9 Pathway and Its Regulatory Mechanisms in Human Breast Cancer by Inna M. Yasinska, Svetlana S. Sakhnevych, Ludmila Pavlova, Anette Teo Hansen Selnø, Ana Maria Teuscher Abeleira, Ana Maria Teuscher Abeleira, Ouafa Benlaouer, Isabel Gonçalves Silva, Marianne Mosimann, Marianne Mosimann, Luca Varani, Marco Bardelli, Rohanah Hussain, Giuliano Siligardi, Dietmar Cholewa, Steffen M. Berger, Bernhard F. Gibbs, Bernhard F. Gibbs, Yuri A. Ushkaryov, Elizaveta Fasler-Kan, Elizaveta Fasler-Kan, Elena Klenova, Vadim V. Sumbayev

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