Absence of BBSome function leads to astrocyte reactivity in the brain by Minati Singh, Janelle E. Garrison, Kai Wang, Val C. Sheffield

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Ciliopathy is differentially distributed in the brain of a Bardet-Biedl syndrome mouse model. by Khristofor Agassandian, Milan Patel, Marianna Agassandian, Karina E Steren, Kamal Rahmouni, Val C Sheffield, J Patrick Card

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Autophagy stimulation reduces ocular hypertension in a murine glaucoma model via autophagic degradation of mutant myocilin by Ramesh B. Kasetti, Prabhavathi Maddineni, Charles Kiehlbauch, Shruti Patil, Charles C. Searby, Beth Levine, Val C. Sheffield, Gulab S. Zode

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Ectopic expression of human BBS4 can rescue Bardet-Biedl syndrome phenotypes in Bbs4 null mice. by Xitiz Chamling, Seongjin Seo, Kevin Bugge, Charles Searby, Deng F Guo, Arlene V Drack, Kamal Rahmouni, Val C Sheffield

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The BBSome Controls Energy Homeostasis by Mediating the Transport of the Leptin Receptor to the Plasma Membrane. by Deng-Fu Guo, Huxing Cui, Qihong Zhang, Donald A Morgan, Daniel R Thedens, Darryl Nishimura, Justin L Grobe, Val C Sheffield, Kamal Rahmouni

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Nuclear/cytoplasmic transport defects in BBS6 underlie congenital heart disease through perturbation of a chromatin remodeling protein. by Charles Anthony Scott, Autumn N Marsden, Michael R Rebagliati, Qihong Zhang, Xitiz Chamling, Charles C Searby, Lisa M Baye, Val C Sheffield, Diane C Slusarski

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BBSome function is required for both the morphogenesis and maintenance of the photoreceptor outer segment. by Ying Hsu, Janelle E Garrison, Gunhee Kim, Addison R Schmitz, Charles C Searby, Qihong Zhang, Poppy Datta, Darryl Y Nishimura, Seongjin Seo, Val C Sheffield

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ATF4 leads to glaucoma by promoting protein synthesis and ER client protein load by Ramesh B. Kasetti, Pinkal D. Patel, Prabhavathi Maddineni, Shruti Patil, Charles Kiehlbauch, J. Cameron Millar, Charles C. Searby, VijayKrishna Raghunathan, Val C. Sheffield, Gulab S. Zode

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Identification and functional analysis of the vision-specific BBS3 (ARL6) long isoform. by Pamela R Pretorius, Lisa M Baye, Darryl Y Nishimura, Charles C Searby, Kevin Bugge, Baoli Yang, Robert F Mullins, Edwin M Stone, Val C Sheffield, Diane C Slusarski

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Calmodulin Methyltransferase Is Required for Growth, Muscle Strength, Somatosensory Development and Brain Function. by Sitvanit Haziza, Roberta Magnani, Dima Lan, Omer Keinan, Ann Saada, Eli Hershkovitz, Nurit Yanay, Yoram Cohen, Yoram Nevo, Robert L Houtz, Val C Sheffield, Hava Golan, Ruti Parvari

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The BBSome regulates mitochondria dynamics and function by Deng-Fu Guo, Ronald A. Merrill, Lan Qian, Ying Hsu, Qihong Zhang, Zhihong Lin, Daniel R. Thedens, Yuriy M. Usachev, Isabella Grumbach, Val C. Sheffield, Stefan Strack, Kamal Rahmouni

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Subretinal gene therapy delays vision loss in a Bardet-Biedl Syndrome type 10 mouse model by Ying Hsu, Sajag Bhattarai, Jacob M. Thompson, Angela Mahoney, Jacintha Thomas, Sara K. Mayer, Poppy Datta, Janelle Garrison, Charles C. Searby, Luk H. Vandenberghe, Seongjin Seo, Val C. Sheffield, Arlene V. Drack

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Progressive retinal degeneration of rods and cones in a Bardet-Biedl syndrome type 10 mouse model by Sara K. Mayer, Jacintha Thomas, Megan Helms, Aishwarya Kothapalli, Ioana Cherascu, Adisa Salesevic, Elliot Stalter, Kai Wang, Poppy Datta, Charles Searby, Seongjin Seo, Ying Hsu, Sajag Bhattarai, Val C. Sheffield, Arlene V. Drack

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An open source and convenient method for the wide-spread testing of COVID-19 using deep throat sputum samples by Sunny C. Huang, Thomas K. Pak, Cameron P. Graber, Charles C. Searby, Guanghao Liu, Jennifer Marcy, Alexandra K. Yaszemski, Kurt Bedell, Emily Bui, Stanley Perlman, Qihong Zhang, Kai Wang, Val C. Sheffield, Calvin S. Carter

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Lentiviral mediated delivery of CRISPR/Cas9 reduces intraocular pressure in a mouse model of myocilin glaucoma by Shruti V. Patil, Balasankara Reddy Kaipa, Sujata Ranshing, Yogapriya Sundaresan, J. Cameron Millar, Bhavani Nagarajan, Charles Kiehlbauch, Qihong Zhang, Ankur Jain, Charles C. Searby, Todd E. Scheetz, Abbot F. Clark, Val C. Sheffield, Gulab S. Zode

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A mouse model of Bardet-Biedl Syndrome has impaired fear memory, which is rescued by lithium treatment. by Thomas K Pak, Calvin S Carter, Qihong Zhang, Sunny C Huang, Charles Searby, Ying Hsu, Rebecca J Taugher, Tim Vogel, Christopher C Cychosz, Rachel Genova, Nina N Moreira, Hanna Stevens, John A Wemmie, Andrew A Pieper, Kai Wang, Val C Sheffield

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A genome-wide association study for primary open angle glaucoma and macular degeneration reveals novel Loci. by Todd E Scheetz, John H Fingert, Kai Wang, Markus H Kuehn, Kevin L Knudtson, Wallace L M Alward, H Culver Boldt, Stephen R Russell, James C Folk, Thomas L Casavant, Terry A Braun, Abbot F Clark, Edwin M Stone, Val C Sheffield

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Osteoarthritis-Like Changes in Bardet–Biedl Syndrome Mutant Ciliopathy Mice (Bbs1M390R/M390R): Evidence for a Role of Primary Cilia in Cartilage Homeostasis and Regulation of Infla... by Isaac D. Sheffield, Mercedes A. McGee, Steven J. Glenn, Da Young Baek, Joshua M. Coleman, Bradley K. Dorius, Channing Williams, Brandon J. Rose, Anthony E. Sanchez, Michael A. Goodman, John M. Daines, Dennis L. Eggett, Val C. Sheffield, Arminda Suli, David L. Kooyman

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Exome-based investigation of the genetic basis of human pigmentary glaucoma by Carly van der Heide, Wes Goar, Kacie J. Meyer, Wallace L. M. Alward, Erin A. Boese, Nathan C. Sears, Ben R. Roos, Young H. Kwon, Adam P. DeLuca, Owen M. Siggs, Claudia Gonzaga-Jauregui, Val C. Sheffield, Kai Wang, Edwin M. Stone, Robert F. Mullins, Michael G. Anderson, Bao Jian Fan, Robert Ritch, Jamie E. Craig, Janey L. Wiggs, Todd E. Scheetz, John H. Fingert

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