Liquid Luminescent DNA-precipitation Assay by Frédérique Végran, Mélanie Bruchard, Valentin Derangère, François Ghiringhelli

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Proximity Ligation Assay (PLA) Protocol Using Duolink® for T Cells by Valentin Derangère, Mélanie Bruchard, Frédérique Végran, François Ghiringhelli

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Cathepsin B Is Required for NLRP3 Inflammasome Activation in Macrophages, Through NLRP3 Interaction by Angélique Chevriaux, Angélique Chevriaux, Thomas Pilot, Thomas Pilot, Valentin Derangère, Valentin Derangère, Valentin Derangère, Harmonie Simonin, Harmonie Simonin, Pierre Martine, Pierre Martine, Fanny Chalmin, François Ghiringhelli, François Ghiringhelli, François Ghiringhelli, Cédric Rébé, Cédric Rébé, Cédric Rébé

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Preliminary evaluation of deep learning for first-line diagnostic prediction of tumor mutational status by Louis-Oscar Morel, Valentin Derangère, Laurent Arnould, Sylvain Ladoire, Nathan Vinçon

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Evaluation of tumor immune contexture among intrinsic molecular subtypes helps to predict outcome in early breast cancer by Francois Ghiringhelli, Valentin Derangere, Quentin Klopfenstein, Emeric Limagne, Marion Thibaudin, Caroline Truntzer, Laurent Arnould, Sylvain Ladoire

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PIK3CA and PIK3R1 tumor mutational landscape in a pan-cancer patient cohort and its association with pathway activation and treatment efficacy by Zoé Tharin, Corentin Richard, Valentin Derangère, Alis Ilie, Laurent Arnould, François Ghiringhelli, Romain Boidot, Sylvain Ladoire

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Radiotherapy Scheme Effect on PD-L1 Expression for Locally Advanced Rectal Cancer by Jihane Boustani, Valentin Derangère, Aurélie Bertaut, Olivier Adotevi, Véronique Morgand, Céline Charon-Barra, François Ghiringhelli, Céline Mirjolet

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CD3-CD8 immune score associated with a clinical score stratifies PDAC prognosis regardless of adjuvant or neoadjuvant chemotherapy by Coralie Schoumacher, Valentin Derangère, Gwladys Gaudillière-Le Dain, Titouan Huppe, David Rageot, Alis Ilie, Angélique Vienot, Christophe Borg, Franck Monnien, Frederic Bibeau, Caroline Truntzer, François Ghiringhelli

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Machine learning evaluation of immune infiltrate through digital tumour score allows prediction of survival outcome in a pooled analysis of three international stage III colon canc... by Julie Lecuelle, Caroline Truntzer, Debora Basile, Luigi Laghi, Luana Greco, Alis Ilie, David Rageot, Jean-François Emile, Fréderic Bibeau, Julien Taïeb, Valentin Derangere, Come Lepage, François Ghiringhelli

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Sirtuin-1 Activation Controls Tumor Growth by Impeding Th17 Differentiation via STAT3 Deacetylation by Emeric Limagne, Marion Thibaudin, Romain Euvrard, Hélène Berger, Pauline Chalons, Frédérique Végan, Etienne Humblin, Romain Boidot, Cédric Rébé, Valentin Derangère, Sylvain Ladoire, Lionel Apetoh, Dominique Delmas, François Ghiringhelli

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Deep Multiple Instance Learning Model to Predict Outcome of Pancreatic Cancer Following Surgery by Caroline Truntzer, Dina Ouahbi, Titouan Huppé, David Rageot, Alis Ilie, Chloe Molimard, Françoise Beltjens, Anthony Bergeron, Angelique Vienot, Christophe Borg, Franck Monnien, Frédéric Bibeau, Valentin Derangère, François Ghiringhelli

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Molecular intrinsic subtypes, genomic, and immune landscapes of BRCA-proficient but HRD-high ER-positive/HER2-negative early breast cancers by Elise Ballot, Loïck Galland, Hugo Mananet, Romain Boidot, Laurent Arnould, Isabelle Desmoulins, Didier Mayeur, Courèche Kaderbhai, Silvia Ilie, Audrey Hennequin, Anthony Bergeron, Valentin Derangère, François Ghiringhelli, Caroline Truntzer, Sylvain Ladoire

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Efficacy of platinum-based chemotherapy in metastatic breast cancer and HRD biomarkers: utility of exome sequencing by Loïck Galland, Elise Ballot, Hugo Mananet, Romain Boidot, Julie Lecuelle, Juliette Albuisson, Laurent Arnould, Isabelle Desmoulins, Didier Mayeur, Courèche Kaderbhai, Silvia Ilie, Audrey Hennequin, Anthony Bergeron, Valentin Derangère, François Ghiringhelli, Caroline Truntzer, Sylvain Ladoire

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Case report: Immune response characterization of a pseudoprogression in a PD-L1-negative, TMB-low, KEAP1/STK11 co-mutated metastatic NSCLC by Nicolas Roussot, Nicolas Roussot, Nicolas Roussot, Nicolas Roussot, Marion Thibaudin, Marion Thibaudin, Jean-David Fumet, Jean-David Fumet, Jean-David Fumet, Jean-David Fumet, Susy Daumoine, Susy Daumoine, Léa Hampe, Léa Hampe, Cédric Rébé, Cédric Rébé, Emeric Limagne, Emeric Limagne, Emeric Limagne, Aurélie Lagrange, Victor Herreros, Julie Lecuelle, Julie Lecuelle, Hugo Mananet, Hugo Mananet, Alis Ilie, Alis Ilie, David Rageot, David Rageot, Romain Boidot, Romain Boidot, Vincent Goussot, Anthony Comte, Pierre Jacob, Pierre Jacob, Pierre Jacob, Pierre Jacob, Françoise Beltjens, Anthony Bergeron, Céline Charon-Barra, Laurent Arnould, Valentin Derangère, Valentin Derangère, Valentin Derangère, Sylvain Ladoire, Sylvain Ladoire, Sylvain Ladoire, Sylvain Ladoire, Caroline Truntzer, Caroline Truntzer, François Ghiringhelli, François Ghiringhelli, François Ghiringhelli, François Ghiringhelli

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Exploring the role of ESR1 mutations in metastatic hormone receptor-positive breast cancer T cell immune surveillance disruption by Morgane Lopez, Laurie Spehner, Fabrice André, Julien Viot, Evan Seffar, Amélie Marguier, Elsa Curtit, Guillaume Meynard, Erion Dobi, Sylvain Ladoire, Romain Boidot, Romain Loyon, Valentin Derangere, François-Clément Bidard, Christophe Borg, Laura Mansi, Marie Kroemer

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Follicular helper-T cells restore CD8+-dependent antitumor immunity and anti-PD-L1/PD-1 efficacy by Francois Ghiringhelli, Valentin Derangere, Marion Thibaudin, Caroline Truntzer, Bertrand Routy, Fanny Chalmin, Cédric Rébé, Julie Niogret, Hélène Berger, Romain Mary, Elise Ballot, Christophe Hibos, Léa Hampe, David Rageot, Théo Accogli, Philippe Joubert, James Harker, Frederique Vegran

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Nanostructured lipid carriers based mRNA vaccine leads to a T cell–inflamed tumour microenvironment favourable for improving PD-1/PD-L1 blocking therapy and long-term immunity in a... by Carole Fournier, Marion Mercey-Ressejac, Valentin Derangère, Amal Al Kadi, David Rageot, Christine Charrat, Alexis Leroy, Julien Vollaire, Véronique Josserand, Marie Escudé, Séverine Escaich, François Ghiringhelli, Thomas Decaens, Fabrice P. Navarro, Evelyne Jouvin-Marche, Patrice N. Marche

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Advancing precision oncology through systematic germline and tumor genetic analysis: The oncogenetic point of view on findings from a prospective multicenter clinical trial of 666... by Benoit Mazel, Geoffrey Bertolone, Amandine Baurand, Elodie Cosset, Caroline Sawka, Marion Robert, Elodie Gautier, Allan Lançon, Manon Réda, Laure Favier, Valentin Dérangère, Corentin Richard, Christine Binquet, Romain Boidot, Vincent Goussot, Juliette Albuisson, François Ghiringhelli, Laurence Faivre, Sophie Nambot

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Safety and efficacy of trifluridine/tipiracil +/− bevacizumab plus XB2001 (anti-IL-1α antibody): a single-center phase 1 trial by Marion Thibaudin, Nicolas Roussot, Chloé Burlot, Antonin Schmitt, Julie Vincent, Zoé Tharin, Leila Bengrine, Hélène Bellio, Aurélie Bertaut, Léa Hampe, Susy Daumoine, Emilie Rederstorff, Morgane Peroz, Titouan Huppe, Valentin Derangère, David Rageot, John Simard, Caroline Truntzer, Jean David Fumet, Francois Ghiringhelli

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Downregulation of Elovl5 promotes breast cancer metastasis through a lipid-droplet accumulation-mediated induction of TGF-β receptors by Trinh-Le-Vi Kieu, Léa Pierre, Valentin Derangère, Sabrina Perrey, Caroline Truntzer, Antoine Jalil, Sébastien Causse, Emma Groetz, Adélie Dumont, Laura Guyard, Laurent Arnould, Jean-Paul Pais de Barros, Lionel Apetoh, Cédric Rébé, Emeric Limagne, Tony Jourdan, Laurent Demizieux, David Masson, Charles Thomas, François Ghiringhelli, Mickaël Rialland

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