Practical aspects of chimeric antigen receptor T-cell administration: From commercial to point-of-care manufacturing by Nuria Martinez-Cibrian, Nuria Martinez-Cibrian, Marta Español-Rego, Mariona Pascal, Mariona Pascal, Julio Delgado, Julio Delgado, Julio Delgado, Valentín Ortiz-Maldonado, Valentín Ortiz-Maldonado

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Chemotherapy resistant Burkitt lymphoma: Possible novel therapies including CAR‐T cell infusion by Paulus A. F. Geerts, Nils ’t Hart, Otto Visser, Valentín Ortiz‐Maldonado, Martine E. D. Chamuleau

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Chimeric Antigen Receptor T Cells Targeting CD19 and Ibrutinib for Chronic Lymphocytic Leukemia by Julio Delgado, Miguel Caballero-Baños, Valentín Ortiz-Maldonado, Maria Castellà, Laura Magnano, Manel Juan, Álvaro Urbano-Ispizua

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P1399: INITIAL CLINICAL RESULTS OF EUPLAGIA-1, A PHASE 1/2 TRIAL OF POINT-OF-CARE MANUFACTURED GLPG5201 IN R/R CLL/SLL WITH OR WITHOUT RICHTER’S TRANSFORMATION by Nuria Martinez-Cibrian, Sergi Betriu, Valentín Ortiz-Maldonado, Daniel Esteban, Natalia Tovar, Ana Triguero Moreno, Leticia Alserawan, Mercedes Montoro, Anna Van Muyden, Maike Spoon, Margot Pont, Christian Jacques, Julio Delgado

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Impact of immunological aging on T cell-mediated therapies in older adults with multiple myeloma and lymphoma by Tamas Fulop, Abdullah M Khan, Valentín Ortiz-Maldonado, Marcus Vetter, Rainer Wirth, Fabian Ullrich, Paul J Bröckelmann, Amin T Turki, Elena-Diana Chiru, Bastian von Tresckow, Raul Cordoba, Nina Rosa Neuendorff

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Lymphodepletion – an essential but undervalued part of the chimeric antigen receptor T-cell therapy cycle by Benno Lickefett, Lulu Chu, Valentin Ortiz-Maldonado, Linda Warmuth, Pere Barba, Matteo Doglio, David Henderson, Michael Hudecek, Andreas Kremer, Janet Markman, Magdalena Nauerth, Helene Negre, Carmen Sanges, Philipp B. Staber, Rebecca Tanzi, Julio Delgado, Dirk H. Busch, Jürgen Kuball, Maik Luu, Ulrich Jäger

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Characterization of the endotheliopathy, innate-immune activation and hemostatic imbalance underlying CAR-T cell toxicities: laboratory tools for an early and differential diagnosi... by Alvaro Urbano-Ispizua, Sara Fernández, Pedro Castro, Francesc Fernández-Avilés, Enric Carreras, Adrián Téllez, Valentín Ortiz-Maldonado, Carlos Fernández de Larrea, Julio Delgado, Olaf Penack, Ana Belen Moreno-Castaño, Helena Ventosa, Marta Palomo, Julia Martinez-Sanchez, Alex Ramos, J M Nicolás, Gines Escolar, Maribel Diaz-Ricart

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P1394: RITUXIMAB BASED LYMPHODEPLETION MAY INCREASE ENGRAFTMENT AND EFFICACY OF SECOND INFUSIONS OF CART19 CELLS IN B-CELL ACUTE LYMPHOBLASTIC LEUKEMIA. by Valentín Ortiz-Maldonado, Nuria Martinez-Cibrian, Marta Español-Rego, Guillermo Muñoz-Sanchez, Sergio Navarro, Leticia Alserawan, Maria Castella, Daniel Benitez-Ribas, Laura Magnano, Eva Gine, Luis Gerardo Rodríguez Lobato, Alexandra Martínez Roca, Helena Brillembourg, Mercedes Montoro, Pilar Ayora, Carlos Fernandez de Larrea, Mariona Pascal, Jordi Esteve, Avaro Urbano Ispizua, Manel Juan, Julio Delgado

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P1391: VARNIMCABTAGENE AUTOLEUCEL (VAR-CEL) IN RELAPSED/ REFRACTORY CD19+ NON-HODGKIN LYMPHOMA by Nuria Martinez-Cibrian, Valentín Ortiz-Maldonado, Marta Español-Rego, Daniel Benitez-Ribas, Joan Cid, Miquel Lozano, Sergio Navarro, Laura Magnano, Eva Gine, Juan Gonzalo Correa Saldarriaga, Pablo Mozas, Luis Gerardo Rodríguez Lobato, Helena Brillembourg, Mercedes Montoro, Pilar Ayora, Leticia Alserawan, Alexandra Martínez Roca, Armando Lopez-Guillermo, Avaro Urbano Ispizua, Manel Juan, Mariona Pascal, Julio Delgado

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Post-mortem neuropathologic examination of a 6-case series of CAR T-cell treated patients by Núria Vidal Robau, Gabriela Caballero, Ivan Archilla, Andrea Ladino, Sara Fernández, Valentín Ortiz-Maldonado, Montserrat Rovira, Marta Gómez-Hernando, Julio Delgado, María Suárez-Lledó, Carlos Fernández de Larrea, Olga Balagué, Gerard Frigola, Abel Muñoz, Estrella Ortiz, Teresa Ribalta, Miguel J. Martinez, Maria Angeles-Marcos, Marta Español-Rego, Azucena González, Daniel Benitez-Ribas, Eugenia Martinez-Hernandez, Pedro Castro, Iban Aldecoa

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Best Treatment Option for Patients With Refractory Aggressive B-Cell Lymphoma in the CAR-T Cell Era: Real-World Evidence From GELTAMO/GETH Spanish Groups by Mariana Bastos-Oreiro, Antonio Gutierrez, Juan Luís Reguera, Gloria Iacoboni, Lucía López-Corral, María José Terol, Valentín Ortíz-Maldonado, Jaime Sanz, Luisa Guerra-Dominguez, Rebeca Bailen, Alberto Mussetti, Pau Abrisqueta, Rafael Hernani, Hugo Luzardo, Juan-Manuel Sancho, Javier Delgado-Serrano, Antonio Salar, Carlos Grande, Leyre Bento, Sonia González de Villambrosía, Daniel García-Belmonte, Anna Sureda, Antonio Pérez-Martínez, Pere Barba, Mi Kwon, Alejandro Martín García-Sancho

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Axicabtagene ciloleucel compared to tisagenlecleucel for the treatment of aggressive B-cell lymphoma by Mi Kwon, Gloria Iacoboni, Juan Luis Reguera, Lucía López Corral, Rafael Hernani Morales, Valentín Ortiz-Maldonado, Manuel Guerreiro, Ana Carolina Caballero, María Luisa Guerra Domínguez, Jose Maria Sanchez Pina, Alberto Mussetti, Juan Manuel Sancho, Mariana Bastos-Oreiro, Eva Catala, Javier Delgado, Hugo Luzardo Henriquez, Jaime Sanz, María Calbacho, Rebeca Bailén, Cecilia Carpio, Jose Maria Ribera, Anna Sureda, Javier Briones, Juan Carlos Hernandez-Boluda, Nuria Martínez Cebrián, Jose Luis Diez Martin, Alejandro Martín, Pere Barba

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Development and validation of predictive models of early immune effector cell–associated hematotoxicity by Emily C. Liang, Jennifer J. Huang, Andrew J. Portuguese, Valentín Ortiz-Maldonado, Aya Albittar, Natalie Wuliji, Ryan Basom, Yein Jeon, Qian Wu, Aiko Torkelson, Delaney Kirchmeier, Abigail Chutnik, Barbara Pender, Mohamed Sorror, Joshua A. Hill, Noam E. Kopmar, Rahul Banerjee, Andrew J. Cowan, Damian Green, Ajay K. Gopal, Christina Poh, Mazyar Shadman, Alexandre V. Hirayama, Brian G. Till, Erik L. Kimble, Lorenzo Iovino, Aude G. Chapuis, Folashade Otegbeye, Ryan D. Cassaday, Filippo Milano, Cameron J. Turtle, David G. Maloney, Jordan Gauthier

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