Editorial of Special Issues “Gut Microbiota–Host Interactions: From Symbiosis to Dysbiosis 2.0” by Valentina Zuccaro, Francesca Romana Ponziani, Raffaele Bruno

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HBV and HDV: New Treatments on the Horizon by Valentina Zuccaro, Erika Asperges, Marta Colaneri, Lea Nadia Marvulli, Raffaele Bruno

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Fungal Osteomyelitis: A Systematic Review of Reported Cases by Erika Asperges, Giuseppe Albi, Francesco Truffelli, Andrea Salvaderi, Flavia Puci, Aurelia Sangani, Valentina Zuccaro, Valeria Scotti, Paolo Orsolini, Enrico Brunetti, Raffaele Bruno

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Microbiota in <i>Clostridioides difficile</i>-Associated Diarrhea: Comparison in Recurrent and Non-Recurrent Infections by Alessandra Gazzola, Simona Panelli, Marta Corbella, Cristina Merla, Francesco Comandatore, Annalisa De Silvestri, Antonio Piralla, Valentina Zuccaro, Claudio Bandi, Piero Marone, Patrizia Cambieri

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What prompts clinicians to start antibiotic treatment in COVID-19 patients? An Italian web survey helps us to understand where the doubts lie by Marta Colaneri, Pietro Valsecchi, Marco Vecchia, Alessandro Di Filippo, Valentina Zuccaro, Elena Seminari, Paolo Sacchi, Laura Maiocchi, Massimiliano Fabbiani, Alessandra Ricciardi, Alba Muzzi, Raffaele Bruno

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Gut Microbiota and B Cell Receptor (BCR) Inhibitors for the Treatment of Chronic Lymphocytic Leukemia: Is Biodiversity Correlated with Clinical Response or Immune-Related Adverse E... by Valentina Zuccaro, Greta Petazzoni, Irene Mileto, Marta Corbella, Erika Asperges, Paolo Sacchi, Sara Rattotti, Marzia Varettoni, Irene Defrancesco, Patrizia Cambieri, Fausto Baldanti, Luca Arcaini, Raffaele Bruno

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Performance of Existing Definitions and Tests for the Diagnosis of Invasive Fungal Diseases other than Invasive Candidiasis and Invasive Aspergillosis in Critically Ill, Adult Pati... by Daniele R. Giacobbe, Andrea Cortegiani, Ilias Karaiskos, Toine Mercier, Sofia Tejada, Maddalena Peghin, Cecilia Grecchi, Chiara Rebuffi, Erika Asperges, Valentina Zuccaro, Luigia Scudeller, Matteo Bassetti, the FUNDICU investigators

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Tocilizumab for Treatment of Severe COVID-19 Patients: Preliminary Results from SMAtteo COvid19 REgistry (SMACORE) by Marta Colaneri, Laura Bogliolo, Pietro Valsecchi, Paolo Sacchi, Valentina Zuccaro, Fabio Brandolino, Carlomaurizio Montecucco, Francesco Mojoli, Emanuele Maria Giusti, Raffaele Bruno, the COVID IRCCS San Matteo Pavia Task Force

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Dynamic NLR and PLR in Predicting COVID-19 Severity: A Retrospective Cohort Study by Erika Asperges, Giuseppe Albi, Valentina Zuccaro, Margherita Sambo, Teresa C. Pieri, Matteo Calia, Marta Colaneri, Laura Maiocchi, Federica Melazzini, Angioletta Lasagna, Andrea Peri, Francesco Mojoli, Paolo Sacchi, Raffaele Bruno

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Impact of Pneumococcal Urinary Antigen Testing in COVID-19 Patients: Outcomes from the San Matteo COVID-19 Registry (SMACORE) by Pietro Valsecchi, Marta Colaneri, Valentina Zuccaro, Erika Asperges, Filippo Costanzo, Bianca Mariani, Silvia Roda, Rita Minucci, Francesco Bertuccio, Elia Fraolini, Matteo Bosio, Claudio Tirelli, Tiberio Oggionni, Angelo Corsico, Raffaele Bruno

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Assessing the Efficacy of Early Therapies against SARS-CoV-2 in Hematological Patients: A Real-Life Study from a COVID-19 Referral Centre in Northern Italy by Marta Colaneri, Teresa Chiara Pieri, Silvia Roda, Alessandra Ricciardi, Manuel Gotti, Jacqueline Ferrari, Luca Arcaini, Sara Rattotti, Antonio Piralla, Federica Giardina, Guglielmo Ferrari, Paolo Sacchi, Valentina Zuccaro, Fausto Baldanti, Raffaele Bruno

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Evaluation of HIV-1 integrase resistance emergence and evolution in patients treated with integrase inhibitors by Rossana Scutari, Claudia Alteri, Ilaria Vicenti, Domenico Di Carlo, Valentina Zuccaro, Francesca Incardona, Vanni Borghi, Antonia Bezenchek, Massimo Andreoni, Andrea Antinori, Carlo Federico Perno, Antonio Cascio, Andrea De Luca, Maurizio Zazzi, Maria Mercedes Santoro

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The Bio-Diversity and the Role of Gut Microbiota in Postmenopausal Women with Luminal Breast Cancer Treated with Aromatase Inhibitors: An Observational Cohort Study by Angioletta Lasagna, Mara De Amici, Chiara Rossi, Valentina Zuccaro, Marta Corbella, Greta Petazzoni, Francesco Comandatore, Lucia Sacchi, Giorgia Testa, Elisa Ferraris, Gianpiero Rizzo, Richard Tancredi, Alessandra Ferrari, Marco Lucioni, Paolo Sacchi, Raffaele Bruno, Paolo Pedrazzoli

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Predicting in-hospital mortality from Coronavirus Disease 2019: A simple validated app for clinical use. by Bianca Magro, Valentina Zuccaro, Luca Novelli, Lorenzo Zileri, Ciro Celsa, Federico Raimondi, Mauro Gori, Giulia Cammà, Salvatore Battaglia, Vincenzo Giuseppe Genova, Laura Paris, Matteo Tacelli, Francesco Antonio Mancarella, Marco Enea, Massimo Attanasio, Michele Senni, Fabiano Di Marco, Luca Ferdinando Lorini, Stefano Fagiuoli, Raffaele Bruno, Calogero Cammà, Antonio Gasbarrini

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Competing-risk analysis of coronavirus disease 2019 in-hospital mortality in a Northern Italian centre from SMAtteo COvid19 REgistry (SMACORE) by Valentina Zuccaro, Ciro Celsa, Margherita Sambo, Salvatore Battaglia, Paolo Sacchi, Simona Biscarini, Pietro Valsecchi, Teresa Chiara Pieri, Ilaria Gallazzi, Marta Colaneri, Michele Sachs, Silvia Roda, Erika Asperges, Matteo Lupi, Alessandro Di Filippo, Elena Seminari, Angela Di Matteo, Stefano Novati, Laura Maiocchi, Marco Enea, Massimo Attanasio, Calogero Cammà, Raffaele Bruno

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The Model for Early COvid-19 Recognition (MECOR) Score: A Proof-of-Concept for a Simple and Low-Cost Tool to Recognize a Possible Viral Etiology in Community-Acquired Pneumonia Pat... by Gianluca Sambataro, Mauro Giuffrè, Domenico Sambataro, Andrea Palermo, Giovanna Vignigni, Roberto Cesareo, Nunzio Crimi, Sebastiano Emanuele Torrisi, Carlo Vancheri, Lorenzo Malatino, Michele Colaci, Nicoletta Del Papa, Francesca Pignataro, Erik Roman-Pognuz, Massimiliano Fabbiani, Francesca Montagnani, Chiara Cassol, Lorenzo Cavagna, Valentina Zuccaro, Verena Zerbato, Cristina Maurel, Roberto Luzzati, Stefano Di Bella

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What is the impact of SARS-CoV-2 pandemic on antimicrobial stewardship programs (ASPs)? The results of a survey among a regional network of infectious disease centres by Agnese Comelli, Camilla Genovese, Andrea Lombardi, Chiara Bobbio, Luigia Scudeller, Umberto Restelli, Antonio Muscatello, Spinello Antinori, Paolo Bonfanti, Salvatore Casari, Antonella Castagna, Francesco Castelli, Antonella d’Arminio Monforte, Fabio Franzetti, Paolo Grossi, Matteo Lupi, Paola Morelli, Stefania Piconi, Massimo Puoti, Luigi Pusterla, Angelo Regazzetti, Marco Rizzi, Stefano Rusconi, Valentina Zuccaro, Andrea Gori, Alessandra Bandera, the ASP Lomb Study Group

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Calcineurin Inhibitor-Based Immunosuppression and COVID-19: Results from a Multidisciplinary Cohort of Patients in Northern Italy by Lorenzo Cavagna, Elena Seminari, Giovanni Zanframundo, Marilena Gregorini, Angela Di Matteo, Teresa Rampino, Carlomaurizio Montecucco, Stefano Pelenghi, Barbara Cattadori, Eleonora Francesca Pattonieri, Patrizio Vitulo, Alessandro Bertani, Gianluca Sambataro, Carlo Vancheri, Alessandro Biglia, Emanuele Bozzalla-Cassione, Valentina Bonetto, Maria Cristina Monti, Elena Ticozzelli, Annalisa Turco, Tiberio Oggionni, Angelo Corsico, Francesco Bertuccio, Valentina Zuccaro, Veronica Codullo, Monica Morosini, Carlo Marena, Massimiliano Gnecchi, Carlo Pellegrini, Federica Meloni

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Dysmetabolism, Diabetes and Clinical Outcomes in Patients Cured of Chronic Hepatitis C: A Real‐Life Cohort Study by Luca Valenti, Serena Pelusi, Alessio Aghemo, Sara Gritti, Luisa Pasulo, Cristiana Bianco, Claudia Iegri, Giuliana Cologni, Elisabetta Degasperi, Roberta D’Ambrosio, Paolo delPoggio, Alessandro Soria, Massimo Puoti, Isabella Carderi, Marie Graciella Pigozzi, Canio Carriero, Angiola Spinetti, Valentina Zuccaro, Massimo Memoli, Alessia Giorgini, Mauro Viganò, Maria Grazia Rumi, Tiziana Re, Ombretta Spinelli, Maria Chiara Colombo, Tiziana Quirino, Barbara Menzaghi, Gianpaolo Lorini, Angelo Pan, Antonella D’Arminio Monforte, Elisabetta Buscarini, Aldo Autolitano, Paolo Bonfanti, Natalia Terreni, Gianpiero Aimo, Monia Mendeni, Daniele Prati, Pietro Lampertico, Massimo Colombo, Stefano Fagiuoli, for the NAVIGATORE‐Lombardia Network

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Characterization of long COVID temporal sub-phenotypes by distributed representation learning from electronic health record data: a cohort studyResearch in Context by Arianna Dagliati, Zachary H. Strasser, Zahra Shakeri Hossein Abad, Jeffrey G. Klann, Kavishwar B. Wagholikar, Rebecca Mesa, Shyam Visweswaran, Michele Morris, Yuan Luo, Darren W. Henderson, Malarkodi Jebathilagam Samayamuthu, Bryce W.Q. Tan, Guillame Verdy, Gilbert S. Omenn, Zongqi Xia, Riccardo Bellazzi, Shawn N. Murphy, John H. Holmes, Hossein Estiri, James R. Aaron, Giuseppe Agapito, Adem Albayrak, Giuseppe Albi, Mario Alessiani, Anna Alloni, Danilo F. Amendola, François Angoulvant, Li L.L.J. Anthony, Bruce J. Aronow, Fatima Ashraf, Andrew Atz, Paul Avillach, Paula S. Azevedo, James Balshi, Brett K. Beaulieu-Jones, Douglas S. Bell, Antonio Bellasi, Riccardo Bellazzi, Vincent Benoit, Michele Beraghi, José Luis Bernal-Sobrino, Mélodie Bernaux, Romain Bey, Surbhi Bhatnagar, Alvar Blanco-Martínez, Clara-Lea Bonzel, John Booth, Silvano Bosari, Florence T. Bourgeois, Robert L. Bradford, Gabriel A. Brat, Stéphane Bréant, Nicholas W. Brown, Raffaele Bruno, William A. Bryant, Mauro Bucalo, Emily Bucholz, Anita Burgun, Tianxi Cai, Mario Cannataro, Aldo Carmona, Charlotte Caucheteux, Julien Champ, Jin Chen, Krista Y. Chen, Luca Chiovato, Lorenzo Chiudinelli, Kelly Cho, James J. Cimino, Tiago K. Colicchio, Sylvie Cormont, Sébastien Cossin, Jean B. Craig, Juan Luis Cruz-Bermúdez, Jaime Cruz-Rojo, Arianna Dagliati, Mohamad Daniar, Christel Daniel, Priyam Das, Batsal Devkota, Audrey Dionne, Rui Duan, Julien Dubiel, Scott L. DuVall, Loic Esteve, Hossein Estiri, Shirley Fan, Robert W. Follett, Thomas Ganslandt, Noelia García- Barrio, Lana X. Garmire, Nils Gehlenborg, Emily J. Getzen, Alon Geva, Tobias Gradinger, Alexandre Gramfort, Romain Griffier, Nicolas Griffon, Olivier Grisel, Alba Gutiérrez-Sacristán, Larry Han, David A. Hanauer, Christian Haverkamp, Derek Y. Hazard, Bing He, Darren W. Henderson, Martin Hilka, Yuk-Lam Ho, John H. Holmes, Chuan Hong, Kenneth M. Huling, Meghan R. Hutch, Richard W. Issitt, Anne Sophie Jannot, Vianney Jouhet, Ramakanth Kavuluru, Mark S. Keller, Chris J. Kennedy, Daniel A. Key, Katie Kirchoff, Jeffrey G. Klann, Isaac S. Kohane, Ian D. Krantz, Detlef Kraska, Ashok K. Krishnamurthy, Sehi L'Yi, Trang T. Le, Judith Leblanc, Guillaume Lemaitre, Leslie Lenert, Damien Leprovost, Molei Liu, Ne Hooi Will Loh, Qi Long, Sara Lozano-Zahonero, Yuan Luo, Kristine E. Lynch, Sadiqa Mahmood, Sarah E. Maidlow, Adeline Makoudjou, Alberto Malovini, Kenneth D. Mandl, Chengsheng Mao, Anupama Maram, Patricia Martel, Marcelo R. Martins, Jayson S. Marwaha, Aaron J. Masino, Maria Mazzitelli, Arthur Mensch, Marianna Milano, Marcos F. Minicucci, Bertrand Moal, Taha Mohseni Ahooyi, Jason H. Moore, Cinta Moraleda, Jeffrey S. Morris, Michele Morris, Karyn L. Moshal, Sajad Mousavi, Danielle L. Mowery, Douglas A. Murad, Shawn N. Murphy, Thomas P. Naughton, Carlos Tadeu Breda Neto, Antoine Neuraz, Jane Newburger, Kee Yuan Ngiam, Wanjiku F.M. Njoroge, James B. Norman, Jihad Obeid, Marina P. Okoshi, Karen L. Olson, Gilbert S. Omenn, Nina Orlova, Brian D. Ostasiewski, Nathan P. Palmer, Nicolas Paris, Lav P. Patel, Miguel Pedrera-Jiménez, Emily R. Pfaff, Ashley C. Pfaff, Danielle Pillion, Sara Pizzimenti, Hans U. Prokosch, Robson A. Prudente, Andrea Prunotto, Víctor Quirós-González, Rachel B. Ramoni, Maryna Raskin, Siegbert Rieg, Gustavo Roig-Domínguez, Pablo Rojo, Paula Rubio-Mayo, Paolo Sacchi, Carlos Sáez, Elisa Salamanca, Malarkodi Jebathilagam Samayamuthu, L. Nelson Sanchez-Pinto, Arnaud Sandrin, Nandhini Santhanam, Janaina C.C. Santos, Fernando J. Sanz Vidorreta, Maria Savino, Emily R. Schriver, Petra Schubert, Juergen Schuettler, Luigia Scudeller, Neil J. Sebire, Pablo Serrano-Balazote, Patricia Serre, Arnaud Serret-Larmande, Mohsin Shah, Zahra Shakeri Hossein Abad, Domenick Silvio, Piotr Sliz, Jiyeon Son, Charles Sonday, Andrew M. South, Anastasia Spiridou, Zachary H. Strasser, Amelia L.M. Tan, Bryce W.Q. Tan, Byorn W.L. Tan, Suzana E. Tanni, Deanne M. Taylor, Ana I. Terriza-Torres, Valentina Tibollo, Patric Tippmann, Emma M.S. Toh, Carlo Torti, Enrico M. Trecarichi, Yi-Ju Tseng, Andrew K. Vallejos, Gael Varoquaux, Margaret E. Vella, Guillaume Verdy, Jill-Jênn Vie, Shyam Visweswaran, Michele Vitacca, Kavishwar B. Wagholikar, Lemuel R. Waitman, Xuan Wang, Demian Wassermann, Griffin M. Weber, Martin Wolkewitz, Scott Wong, Zongqi Xia, Xin Xiong, Ye Ye, Nadir Yehya, William Yuan, Alberto Zambelli, Harrison G. Zhang, Daniela Zo¨ller, Valentina Zuccaro, Chiara Zucco

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