Methotrexate-induced side effects are not due to differences in pharmacokinetics in children with Down syndrome and acute lymphoblastic leukemia by Trudy D. Buitenkamp, Ron A.A. Mathôt, Valerie de Haas, Rob Pieters, C. Michel Zwaan

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Low frequency of type-I and type-II aberrations in myeloid leukemia of Down syndrome, underscoring the unique entity of this disease by Marjolein Blink, Marry M. van den Heuvel-Eibrink, Valerie de Haas, Jan-Henning Klusmann, Henrik Hasle, C. Michel Zwaan

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P366: ARE MINIMAL RESIDUAL DISEASE MEASUREMENTS AFTER CONSOLIDATION THERAPY USEFUL IN CHILDREN WITH ACUTE LYMPHOBLASTIC LEUKEMIA? by Janine Stutterheim, Rachella Van der Waarden, Hester de Groot-Kruseman, Edwin Sonneveld, Valerie De Haas, Ellen C Van der Schoot, Vincent van der Velden, Rana Dandis, Rob Pieters

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CircRNAs Dysregulated in Juvenile Myelomonocytic Leukemia: CircMCTP1 Stands Out by Anna Dal Molin, Mattias Hofmans, Mattias Hofmans, Enrico Gaffo, Alessia Buratin, Alessia Buratin, Hélène Cavé, Hélène Cavé, Christian Flotho, Valerie de Haas, Valerie de Haas, Charlotte M. Niemeyer, Jan Stary, Pieter Van Vlierberghe, Pieter Van Vlierberghe, Jan Philippé, Jan Philippé, Barbara De Moerloose, Barbara De Moerloose, Geertruij te Kronnie, Silvia Bresolin, Silvia Bresolin, Tim Lammens, Tim Lammens, Stefania Bortoluzzi, Stefania Bortoluzzi

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Low-dose cytarabine to prevent myeloid leukemia in children with Down syndrome: TMD Prevention 2007 study by Marius Flasinski, Kira Scheibke, Martin Zimmermann, Ursula Creutzig, Katarina Reinhardt, Femke Verwer, Valerie de Haas, Vincent H.J. van der Velden, Christine von Neuhoff, C. Michel Zwaan, Dirk Reinhardt, Jan-Henning Klusmann

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Mapping epigenetic regulator gene mutations in cytogenetically normal pediatric acute myeloid leukemia by Daria G. Valerio, Jenny E. Katsman-Kuipers, Joop H. Jansen, Lonneke J. Verboon, Valerie de Haas, Jan Stary, André Baruchel, Martin Zimmermann, Rob Pieters, Dirk Reinhardt, Marry M. van den Heuvel-Eibrink, C. Michel Zwaan

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Higher ratio immune versus constitutive proteasome level as novel indicator of sensitivity of pediatric acute leukemia cells to proteasome inhibitors by Denise Niewerth, Niels E. Franke, Gerrit Jansen, Yehuda G. Assaraf, Johan van Meerloo, Christopher J. Kirk, Jeremiah Degenhardt, Janet Anderl, Aaron D. Schimmer, Sonja Zweegman, Valerie de Haas, Terzah M. Horton, Gertjan J.L. Kaspers, Jacqueline Cloos

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Gene expression profiles associated with pediatric relapsed AML. by Costa Bachas, Gerrit Jan Schuurhuis, C Michel Zwaan, Marry M van den Heuvel-Eibrink, Monique L den Boer, Eveline S J M de Bont, Zinia J Kwidama, Dirk Reinhardt, Ursula Creutzig, Valérie de Haas, Gertjan J L Kaspers, Jacqueline Cloos

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Long non-coding RNAs as novel therapeutic targets in juvenile myelomonocytic leukemia by Mattias Hofmans, Tim Lammens, Barbara Depreter, Ying Wu, Miriam Erlacher, Aurélie Caye, Hélène Cavé, Christian Flotho, Valerie de Haas, Charlotte M. Niemeyer, Jan Stary, Filip Van Nieuwerburgh, Dieter Deforce, Wouter Van Loocke, Pieter Van Vlierberghe, Jan Philippé, Barbara De Moerloose

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BCOR and BCORL1 mutations in pediatric acute myeloid leukemia by Jasmijn D.E. de Rooij, Marry M. van den Heuvel-Eibrink, Malou C.H. Hermkens, Lonneke J. Verboon, Susan T.C.J.M. Arentsen-Peters, Maarten Fornerod, Andre Baruchel, Jan Stary, Dirk Reinhardt, Valerie de Haas, Rob Pieters, C. Michel Zwaan

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Lack of splice factor and cohesin complex mutations in pediatric myelodysplastic syndrome by Julia C. Obenauer, François G. Kavelaars, Mathijs A. Sanders, Remco M. Hoogenboezem, Andrica C. H. de Vries, Paulina M. H. van Strien, Valerie de Haas, Franco Locatelli, Henrik Hasle, Peter J. M. Valk, Ivo P. Touw, Marry M. van den Heuvel-Eibrink

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Population pharmacokinetics of intravenous Erwinia asparaginase in pediatric acute lymphoblastic leukemia patients by Sebastiaan D.T. Sassen, Ron A.A. Mathôt, Rob Pieters, Robin Q.H. Kloos, Valérie de Haas, Gertjan J.L. Kaspers, Cor van den Bos, Wim J.E. Tissing, Maroeska te Loo, Marc B. Bierings, Wouter J.W. Kollen, Christian M. Zwaan, Inge M. van der Sluis

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Guideline for management of non-Down syndrome neonates with a myeloproliferative disease on behalf of the I-BFM AML Study Group and EWOG-MDS by Eline J.M. Bertrums, C. Michel Zwaan, Daisuke Hasegawa, Valerie de Haas, Dirk N. Reinhardt, Franco Locatelli, Barbara de Moerloose, Michael Dworzak, Arjan Buijs, Petr Smisek, Alexandra Kolenova, Cornelis Jan Pronk, Jan-Henning Klusmann, Ana Carboné, Alina Ferster, Evangelia Antoniou, Soheil Meshinchi, Susana C. Raimondi, Charlotte M. Niemeyer, Henrik Hasle, Marry M. van den Heuvel-Eibrink, Bianca F. Goemans

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Normal karyotype is a poor prognostic factor in myeloid leukemia of Down syndrome: a retrospective, international study by Marjolein Blink, Martin Zimmermann, Christine von Neuhoff, Dirk Reinhardt, Valerie de Haas, Henrik Hasle, Maureen M. O’Brien, Batia Stark, Julie Tandonnet, Andrea Pession, Katerina Tousovska, Daniel K.L. Cheuk, Kazuko Kudo, Takashi Taga, Jeffrey E. Rubnitz, Iren Haltrich, Walentyna Balwierz, Rob Pieters, Erik Forestier, Bertil Johansson, Marry M. van den Heuvel-Eibrink, C. Michel Zwaan

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LIN28B is over-expressed in specific subtypes of pediatric leukemia and regulates lncRNA H19 by Hetty H. Helsmoortel, Barbara De Moerloose, Tim Pieters, Farzaneh Ghazavi, Silvia Bresolin, Hélène Cavé, Andrica de Vries, Valerie de Haas, Christian Flotho, Veerle Labarque, Charlotte Niemeyer, Pascale De Paepe, Nadine Van Roy, Jan Stary, Marry M. van den Heuvel-Eibrink, Yves Benoit, Johannes Schulte, Steven Goossens, Geert Berx, Jody J. Haigh, Frank Speleman, Pieter Van Vlierberghe, Tim Lammens

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GENOTYPE/PHENOTYPE ASSOCIATIONS IN 174 INDIVIDUALS WITH GERMLINE GATA2 MUTATIONS by Lili Kotmayer, Emilia Kozyra, Maximilian Kaiser, Michael Dworzak, Barbara De Moerloose, Jan Starý, Henrik Hasle, Kirsi Jahnukainen, Sophia Polychronopoulou, Krisztián Kállay, Owen Smith, Shlomit Barzilai, Riccardo Masetti, Jochen Buechner, Marek Ussowicz, Paula Kjollerstrom, Ivana Boďová, Marko Kavcic, Albert Catala, Dominik Turkiewicz, Markus Schmugge, Valérie De Haas, Rebecca Voss, Anna Bigas, Damia Romero, Csaba Bödör, Miriam Erlacher, Alessandra Giorgetti, Charlotte Niemeyer, Marcin Wlodarski

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NPM1 MUTATIONS IN CHILDREN WITH MYELODYSPLASTIC SYNDROME WITH EXCESS BLASTS by Ayami Yoshimi, Miriam Erlacher, Peter Noellke, Senthilkumar Ramamoorthy, Gudrun Göhring, Shlomit Barzilai – Birenboim, Ivana Bodova, Jochen Buechner, Albert Catala, Valérie De Haas, Barbara De Moerloose, Michael Dworzak, Henrik Hasle, Kirsi Jahnukainen, Krisztian Kallay, Marko Kavcic, Paula Kjollerstrom, Franco Locatelli, Riccardo Masetti, Sophia Polychronopoulou, Markus Schmugge, Owen Smith, Jan Stary, Dominik Turkiewicz, Marek Ussowicz, Natalia Rotari, Marcin Wlodarski, Brigitte Strahm, Charlotte Niemeyer

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Integrative analysis of type-I and type-II aberrations underscores the genetic heterogeneity of pediatric acute myeloid leukemia by Brian V. Balgobind, Iris H.I.M. Hollink, Susan T.C.J.M. Arentsen-Peters, Martin Zimmermann, Jochen Harbott, H. Berna Beverloo, Anne R.M. von Bergh, Jacqueline Cloos, Gertjan J.L. Kaspers, Valerie de Haas, Zuzana Zemanova, Jan Stary, Jean-Michel Cayuela, Andre Baruchel, Ursula Creutzig, Dirk Reinhardt, Rob Pieters, C. Michel Zwaan, Marry M. van den Heuvel-Eibrink

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M&M: an RNA-seq based pan-cancer classifier for paediatric tumoursResearch in context by Fleur S.A. Wallis, John L. Baker-Hernandez, Marc van Tuil, Claudia van Hamersveld, Marco J. Koudijs, Eugène T.P. Verwiel, Alex Janse, Laura S. Hiemcke-Jiwa, Ronald R. de Krijger, Mariëtte E.G. Kranendonk, Marijn A. Vermeulen, Pieter Wesseling, Uta E. Flucke, Valérie de Haas, Maaike Luesink, Eelco W. Hoving, Josef H. Vormoor, Max M. van Noesel, Jayne Y. Hehir-Kwa, Bastiaan B.J. Tops, Patrick Kemmeren, Lennart A. Kester

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t(6;9)(p22;q34)/DEK-NUP214-rearranged pediatric myeloid leukemia: an international study of 62 patients by Julie Damgaard Sandahl, Eva A. Coenen, Erik Forestier, Jochen Harbott, Bertil Johansson, Gitte Kerndrup, Souichi Adachi, Anne Auvrignon, H. Berna Beverloo, Jean-Michel Cayuela, Lucy Chilton, Maarten Fornerod, Valérie de Haas, Christine J. Harrison, Hiroto Inaba, Gertjan J.L. Kaspers, Der-Cherng Liang, Franco Locatelli, Riccardo Masetti, Christine Perot, Susana C. Raimondi, Katarina Reinhardt, Daisuke Tomizawa, Nils von Neuhoff, Marco Zecca, C. Michel Zwaan, Marry M. van den Heuvel-Eibrink, Henrik Hasle

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