Showing 1 - 5 results of 5 for search 'Vanessa Siegmund', query time: 0.03s Refine Results
  1. 1
    A library approach for the de novo high-throughput isolation of humanized VHH domains with favorable developability properties following camelid immunization

    A library approach for the de novo high-throughput isolation of humanized VHH domains with favorable developability properties following camelid immunization by Paul Arras, Han Byul Yoo, Lukas Pekar, Christian Schröter, Thomas Clarke, Simon Krah, Daniel Klewinghaus, Vanessa Siegmund, Andreas Evers, Stefan Zielonka

    Published 2023-12-01
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  2. 2
    Cattle-derived knob paratopes grafted onto peripheral loops of the IgG1 Fc region enable the generation of a novel symmetric bispecific antibody format

    Cattle-derived knob paratopes grafted onto peripheral loops of the IgG1 Fc region enable the generation of a novel symmetric bispecific antibody format by Desislava Yanakieva, Lena Vollmer, Andreas Evers, Vanessa Siegmund, Paul Arras, Lukas Pekar, Achim Doerner, Bernhard Valldorf, Harald Kolmar, Stefan Zielonka, Stefan Zielonka, Simon Krah

    Published 2023-10-01
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  3. 3
    AI/ML combined with next-generation sequencing of VHH immune repertoires enables the rapid identification of de novo humanized and sequence-optimized single domain antibodies: a prospective case study

    AI/ML combined with next-generation sequencing of VHH immune repertoires enables the rapid identification of de novo humanized and sequence-optimized single domain antibodies: a pr... by Paul Arras, Paul Arras, Han Byul Yoo, Lukas Pekar, Thomas Clarke, Lukas Friedrich, Christian Schröter, Jennifer Schanz, Jason Tonillo, Vanessa Siegmund, Achim Doerner, Simon Krah, Enrico Guarnera, Stefan Zielonka, Stefan Zielonka, Andreas Evers

    Published 2023-09-01
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  4. 4
    Generation and engineering of potent single domain antibody-based bispecific IL-18 mimetics resistant to IL-18BP decoy receptor inhibition

    Generation and engineering of potent single domain antibody-based bispecific IL-18 mimetics resistant to IL-18BP decoy receptor inhibition by Britta Lipinski, Laura Unmuth, Paul Arras, Stefan Becker, Christina Bauer, Lars Toleikis, Simon Krah, Achim Doerner, Desislava Yanakieva, Ammelie Svea Boje, Katja Klausz, Matthias Peipp, Vanessa Siegmund, Andreas Evers, Harald Kolmar, Lukas Pekar, Stefan Zielonka

    Published 2023-12-01
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  5. 5
    A Generic Approach for Miniaturized Unbiased High-Throughput Screens of Bispecific Antibodies and Biparatopic Antibody–Drug Conjugates

    A Generic Approach for Miniaturized Unbiased High-Throughput Screens of Bispecific Antibodies and Biparatopic Antibody–Drug Conjugates by Nadine Barron, Stephan Dickgiesser, Markus Fleischer, Angelika-Nicole Bachmann, Daniel Klewinghaus, Jens Hannewald, Elke Ciesielski, Ilja Kusters, Til Hammann, Volker Krause, Sebastian Winfried Fuchs, Vanessa Siegmund, Alec W. Gross, Dirk Mueller-Pompalla, Simon Krah, Stefan Zielonka, Achim Doerner

    Published 2024-02-01
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