Intratracheal Administration of siRNA Triggers mRNA Silencing in the Lung to Modulate T Cell Immune Response and Lung Inflammation by Bruce Ng, Tanesha Cash-Mason, Yi Wang, Jessica Seitzer, Julja Burchard, Duncan Brown, Vadim Dudkin, Joseph Davide, Vasant Jadhav, Laura Sepp-Lorenzino, Pedro J. Cejas

Get full text

Silencing Myostatin Using Cholesterol-conjugated siRNAs Induces Muscle Growth by Tayeba Khan, Hans Weber, Jillian DiMuzio, Andrea Matter, Belma Dogdas, Tosha Shah, Anil Thankappan, Jyoti Disa, Vasant Jadhav, Laura Lubbers, Laura Sepp-Lorenzino, Walter R Strapps, Marija Tadin-Strapps

Get full text

Selection of GalNAc-conjugated siRNAs with limited off-target-driven rat hepatotoxicity by Maja M. Janas, Mark K. Schlegel, Carole E. Harbison, Vedat O. Yilmaz, Yongfeng Jiang, Rubina Parmar, Ivan Zlatev, Adam Castoreno, Huilei Xu, Svetlana Shulga-Morskaya, Kallanthottathil G. Rajeev, Muthiah Manoharan, Natalie D. Keirstead, Martin A. Maier, Vasant Jadhav

Get full text

RNAi-mediated rheostat for dynamic control of AAV-delivered transgenes by Megha Subramanian, James McIninch, Ivan Zlatev, Mark K. Schlegel, Charalambos Kaittanis, Tuyen Nguyen, Saket Agarwal, Timothy Racie, Martha Arbaiza Alvarado, Kelly Wassarman, Thomas S. Collins, Tyler Chickering, Christopher R. Brown, Karyn Schmidt, Adam B. Castoreno, Svetlana Shulga-Morskaya, Elena Stamenova, Kira Buckowing, Daniel Berman, Joseph D. Barry, Anna Bisbe, Martin A. Maier, Kevin Fitzgerald, Vasant Jadhav

Get full text

Pharmacological Characterization of a Novel ENaCα siRNA (GSK2225745) With Potential for the Treatment of Cystic Fibrosis by Kenneth L Clark, Stephen A Hughes, Pallav Bulsara, Jill Coates, Kitty Moores, Joel Parry, Michael Carr, Ruth J Mayer, Paul Wilson, Chris Gruenloh, Daren Levin, Jill Darton, Wolf-Michael Weber, Katja Sobczak, Deborah R Gill, Stephen C Hyde, Lee A Davies, Ian A Pringle, Stephanie G Sumner-Jones, Vasant Jadhav, Sharon Jamison, Walter R Strapps, Victoria Pickering, Mark R Edbrooke

Get full text