The flavivirus NS2B–NS3 protease–helicase as a target for antiviral drug development 由 Luo, Dahai, Vasudevan, Subhash, Lescar, Julien

获取全文
获取全文

Expression and immunoaffinity purification of recombinant dengue virus 2 NS1 protein as a cleavable SUMOstar fusion 由 Rozen-Gagnon, Kathryn, Ruedl, Christiane, Moreland, Nicole J., Vasudevan, Subhash G.

获取全文
获取全文

Zika virus nonstructural protein 5 residue R681 is critical for dimer formation and enzymatic activity 由 Saw, Wuan-Geok, Chan, Kitti Wing-Ki, Vasudevan, Subhash G., Grüber, Gerhard

获取全文

Dengue virus serotype infection specifies the activation of the unfolded protein response 由 Chevet Eric, Vasudevan Subhash G, Wang Qing, Pluquet Olivier, Umareddy Indira, Gu Feng

获取全文

The magnitude of dengue virus NS1 protein secretion is strain dependent and does not correlate with severe pathologies in the mouse infection model 由 Watanabe, Satoru, Tan, Kah Hin, Rathore, Abhay P. S., Rozen-Gagnon, Kathryn, Shuai, Wang, Ruedl, Christiane, Vasudevan, Subhash G.

获取全文
获取全文

Luteolin escape mutants of dengue virus map to prM and NS2B and reveal viral plasticity during maturation 由 Vasudevan, Subhash G., Peng, Minhua, Swarbrick, Crystall Marie Dawn, Chan, Kitti Wing-Ki, Luo, Dahai, Zhang, Wei, Lai, Xiaoping, Li, Geng

获取全文
获取全文

Crystal structures of full length DENV4 NS2B-NS3 reveal the dynamic interaction between NS2B and NS3 由 Phoo, Wint Wint, El Sahili, Abbas, Zhang, ZhenZhen, Chen, Ming Wei, Liew, Chong Wai, Lescar, Julien, Vasudevan, Subhash G., Luo, Dahai

获取全文

A conserved arginine in NS5 binds genomic 3' stem-loop RNA for primer-independent initiation of flavivirus RNA replication 由 Wang, Sai, Chan, Kitti Wing Ki, Tan, Min Jie Alvin, Flory, Charlotte, Luo, Dahai, Lescar, Julian, Forwood, Jade K., Vasudevan, Subhash G.

获取全文

Molecular basis for specific viral RNA recognition and 2' -O-ribose methylation by the dengue virus nonstructural protein 5 (NS5) 由 Zhao, Yongqian, Soh, Tingjin Sherryl, Lim, Siew Pheng, Chung, Ka Yan, Swaminathan, Kunchithapadam, Vasudevan, Subhash G., Shi, Pei-Yong, Lescar, Julien, Luo, Dahai

获取全文
获取全文

Luteolin restricts dengue virus replication through inhibition of the proprotein convertase furin 由 Peng, Minhua, Watanabe, Satoru, Chan, Kitti Wing Ki, He, Qiuyan, Zhao, Ya, Zhang, Zhongde, Lai, Xiaoping, Luo, Dahai, Vasudevan, Subhash G., Li, Geng

获取全文
获取全文

Non-nucleoside inhibitors of Zika virus RNA-dependent RNA polymerase 由 Gharbi-Ayachi, Aïcha, Santhanakrishnan, Sridhar, Wong, Yee Hwa, Chan, Kitti Wing Ki, Tan, Siok Thing, Bates, Roderick Wayland, Vasudevan, Subhash G., El Sahili, Abbas, Lescar, Julien

获取全文

NS3 helicase from dengue virus specifically recognizes viral RNA sequence to ensure optimal replication 由 Swarbrick, Crystall M. D., Basavannacharya, Chandrakala, Chan, Kitti W. K., Chan, Shu-Ann, Singh, Daljit, Wei, Na, Phoo, Wint Wint, Luo, Dahai, Lescar, Julien, Vasudevan, Subhash G.

获取全文
获取全文

Structural insight and flexible features of NS5 proteins from all four serotypes of Dengue virus in solution 由 Saw, Wuan Geok, Tria, Giancarlo, Grüber, Ardina, Subramanian Manimekalai, Malathy Sony, Zhao, Yongqian, Chandramohan, Arun, Srinivasan Anand, Ganesh, Matsui, Tsutomu, Weiss, Thomas M., Vasudevan, Subhash G., Grüber, Gerhard

获取全文
获取全文

Flexibility of NS5 Methyltransferase-Polymerase Linker Region Is Essential for Dengue Virus Replication 由 Zhao, Yongqian, Soh, Tingjin Sherryl, Chan, Kitti Wing Ki, Fung, Sarah Suet Yin, Swaminathan, Kunchithapadam, Lim, Siew Pheng, Shi, Pei-Yong, Huber, Thomas, Lescar, Julien, Luo, Dahai, Vasudevan, Subhash G.

获取全文
获取全文

The C-terminal 18 Amino Acid Region of Dengue Virus NS5 Regulates its Subcellular Localization and Contains a Conserved Arginine Residue Essential for Infectious Virus Production 由 Chan, Kitti W. K., Tay, Moon Y. F., Smith, Kate, Ng, Ivan H. W., Zhao, Yongqian, Ooi, Eng Eong, Lescar, Julien, Luo, Dahai, Jans, David A., Forwood, Jade K., Vasudevan, Subhash G.

获取全文
获取全文

The C-terminal 50 amino acid residues of dengue NS3 protein are important for NS3-NS5 interaction and viral replication 由 Tay, Moon Y. F., Saw, Wuan Geok, Zhao, Yongqian, Chan, Kitti W. K., Singh, Daljit, Chong, Yuwen, Forwood, Jade K., Ooi, Eng Eong, Grüber, Gerhard, Lescar, Julien, Luo, Dahai, Vasudevan, Subhash G.

获取全文
获取全文

Cell-active carbazole derivatives as inhibitors of the zika virus protease 由 Rassias, Gerasimos, Zogali, Vasiliki, Swarbrick, Crystall M. D., Chan, Kitti Wing Ki, Chan, Shu Ann, Gwee, Chin Piaw, Wang, Sai, Kaplanai, Entzy, Canko, Aleksander, Kiousis, Dimitrios, Lescar, Julien, Luo, Dahai, Matsoukas, Minos-Timotheos, Vasudevan, Subhash G.

获取全文

A crystal structure of the dengue virus NS5 protein reveals a novel inter-domain interface essential for protein flexibility and virus replication 由 Zhao, Yongqian, Soh, Tingjin Sherryl, Zheng, Jie, Chan, Kitti Wing Ki, Phoo, Wint Wint, Lee, Chin Chin, Tay, Moon Y. F., Swaminathan, Kunchithapadam, Cornvik, Tobias Carl, Lim, Siew Pheng, Shi, Pei-Yong, Lescar, Julien, Vasudevan, Subhash G., Luo, Dahai

获取全文
获取全文

Rational engineering and characterization of an mAb that neutralizes Zika virus by targeting a mutationally constrained quaternary epitope 由 Tharakaraman, Kannan, Watanabe, Satoru, Chan, Kuan Rong, Huan, Jia, Subramanian, Vidya, Chionh, Yok Hian, Raguram, Aditya, Quinlan, Devin, McBee, Megan, Ong, Eugenia Z., Gan, Esther S., Tan, Hwee Cheng, Tyagi, Anu, Bhushan, Shashi, Lescar, Julien, Vasudevan, Subhash G., Ooi, Eng Eong, Sasisekharan, Ram

获取全文

Rational Engineering and Characterization of an mAb that Neutralizes Zika Virus by Targeting a Mutationally Constrained Quaternary Epitope 由 Watanabe, Satoru, Chan, Kuan Rong, Huan, Jia, Chionh, Yok Hian, Raguram, Aditya, McBee, Megan, Ong, Eugenia Z., Gan, Esther S., Tan, Hwee Cheng, Tyagi, Anu, Bhushan, Shashi, Lescar, Julien, Vasudevan, Subhash G., Ooi, Eng Eong, Tharakaraman, Kannan, Subramanian, Vidya, Quinlan, Devin Scott, Sasisekharan, Ram

获取全文
获取全文
获取全文