Torthaí cuardaigh údar :: UTM Library Massive Scholar Tracking

1

Integrative proximal-ubiquitomics profiling for deubiquitinase and E3 ligase substrate discovery applied to USP30 de réir Damianou, A, Jones, H, Grigoriou, A, Vendrell, I, Davis, S, Kessler, B

Foilsithe / Cruthaithe 2024

Internet publication

2

Modulation of proteostasis counteracts oxidative stress and affects DNA base excision repair capacity in ATM-deficient cells de réir Poletto, M, Yang, D, Fletcher, S, Vendrell, I, Fischer, R, Legrand, A, Dianov, G

Foilsithe / Cruthaithe 2017

Journal article

3

Data-independent acquisition proteomics of cerebrospinal fluid implicates endoplasmic reticulum and inflammatory mechanisms in amyotrophic lateral sclerosis de réir Dellar, ER, Vendrell, I, Talbot, K, Kessler, B, Fischer, R, Turner, MR, Thompson, AG

Foilsithe / Cruthaithe 2023

Journal article

4

RASSF1A is required for the maintenance of nuclear actin levels de réir Chatzifrangkeskou, M, Pefani, D, Eyres, M, Vendrell, I, Fischer, R, Pankova, D, O'Neill, E

Foilsithe / Cruthaithe 2019

Journal article

5

RASSF1A controls tissue stiffness and cancer stem‐like cells in lung adenocarcinoma de réir Pankova, D, Jiang, Y, Chatzifrangkeskou, M, Vendrell, I, Buzzelli, J, Ryan, A, Brown, C, O'Neill, E

Foilsithe / Cruthaithe 2019

Journal article

6

SPRTN protease-cleaved MRE11 decreases DNA repair and radiosensitises cancer cells de réir Na, J, Newman, J, Then, CK, Syed, J, Vendrell, I, Torrecilla, I, Ellermann, S, Ramadan, K, Fischer, R, Kiltie, A

Foilsithe / Cruthaithe 2021

Journal article

7

p97/VCP inhibition causes excessive MRE11-dependent DNA end resection promoting cell killing after ionizing radiation de réir Kilgas, S, Singh, AN, Paillas, S, Then, C-K, Torrecilla, I, Nicholson, J, Browning, L, Vendrell, I, Konietzny, R, Kiltie, AE, Ramadan, K

Foilsithe / Cruthaithe 2021

Journal article

8

BLM and BRCA1-BARD1 coordinate complementary mechanisms of joint DNA molecule resolution de réir Tsukada, K, Jones, SE, Bannister, J, Durin, M-A, Vendrell, I, Fawkes, M, Fischer, R, Kessler, BM, Chapman, JR, Blackford, AN

Foilsithe / Cruthaithe 2024

Journal article

9

Disease-associated KBTBD4 mutations in medulloblastoma elicit neomorphic ubiquitylation activity to promote CoREST degradation de réir Chen, Z, Ioris, RM, Richardson, S, Van Ess, AN, Vendrell, I, Kessler, BM, Buffa, FM, Busino, L, Clifford, SC, Bullock, AN, D'Angiolella, V

Foilsithe / Cruthaithe 2022

Journal article

10

Oncogenic mutations of KRAS modulate its turnover by the CUL3/LZTR1 E3 ligase complex de réir Damianou, A, Liang, Z, Lassen, F, Vendrell, I, Vere, G, Hester, S, Charles, PD, Pinto-Fernandez, A, Santos, A, Fischer, R, Kessler, BM

Foilsithe / Cruthaithe 2024

Journal article

11

Tumor imaging using radiolabelled matrix metalloproteinase-activated anthrax proteins de réir Xavier, M, Liu, S, Bugge, T, Baguna-Torres, J, Mosley, M, Hopkins, S, Allen, P, Berridge, G, Vendrell, I, Fischer, R, Kersemans, V, Smart, S, Leppla, S, Cornelissen, B

Foilsithe / Cruthaithe 2019

Journal article

12

Cyclin F–EXO1 axis controls cell cycle–dependent execution of double-strand break repair de réir Yang, H, Fouad, S, Smith, P, Bae, EY, Ji, Y, Lan, X, Van Ess, A, Buffa, FM, Fischer, R, Vendrell, I, Kessler, BM, D’Angiolella, V

Foilsithe / Cruthaithe 2024

Journal article

13

USP18 is an essential regulator of muscle cell differentiation and maturation de réir Olie, CS, Pinto-Fernández, A, Damianou, A, Vendrell, I, Mei, H, den Hamer, B, van der Wal, E, de Greef, JC, Raz, V, Kessler, BM

Foilsithe / Cruthaithe 2023

Journal article

14

Elevated cerebrospinal fluid ubiquitin carboxyl-terminal hydrolase isozyme L1 in asymptomatic C9orf72 hexanucleotide repeat expansion carriers de réir Dellar, ER, Vendrell, I, Amein, B, Lester, DG, Yoganathan, K, Dharmadasa, T, Sogorb‐Esteve, A, Fischer, R, Talbot, K, Rohrer, JD, Turner, MR, Thompson, AG, Edmond, EC

Foilsithe / Cruthaithe 2024

Journal article

15

Structural premise of selective deubiquitinase USP30 inhibition by small-molecule benzosulfonamides de réir O’Brien, DP, Jones, HBL, Guenther, F, Murphy, EJ, England, KS, Vendrell, I, Anderson, M, Brennan, PE, Davis, JB, Pinto-Fernández, A, Turnbull, AP, Kessler, BM

Foilsithe / Cruthaithe 2023

Journal article

16

Covalent fragment screening and optimization identifies the chloroacetohydrazide scaffold as inhibitors for ubiquitin C-terminal hydrolase L1 de réir Imhoff, RD, Patel, R, Safdar, MH, Jones, HBL, Pinto-Fernandez, A, Vendrell, I, Chen, H, Muli, CS, Krabill, AD, Kessler, BM, Wendt, MK, Das, C, Flaherty, DP

Foilsithe / Cruthaithe 2024

Journal article

17

E2F1 proteolysis via SCF-cyclin F underlies synthetic lethality between cyclin F loss and Chk1 inhibition de réir Burdova, K, Yang, H, Faedda, R, Hume, S, Chauhan, J, Ebner, D, Kessler, B, Vendrell, I, Drewry, D, Wells, C, Hatch, S, Dianov, G, Buffa, F, D'Angiolella, V

Foilsithe / Cruthaithe 2019

Journal article

18

SPRTN protease and checkpoint kinase 1 cross-activation loop safeguards DNA replication de réir Halder, S, Torrecilla, I, Burkhalter, MD, Popović, M, Fielden, J, Vaz, B, Oehler, J, Pilger, D, Lessel, D, Wiseman, K, Singh, AN, Vendrell, I, Fischer, R, Philipp, M, Ramadan, K

Foilsithe / Cruthaithe 2019

Journal article

19

TEX264 coordinates p97- and SPRTN-mediated resolution of topoisomerase 1-DNA adducts de réir Fielden, J, Wiseman, K, Torrecilla, I, Li, S, Hume, S, Chiang, SC, Ruggiano, A, Singh, AN, Freire, R, Hassanieh, S, Domingo, E, Vendrell, I, Fischer, R, Kessler, BM, Maughan, TS, El-Khamisy, SF, Ramadan, K

Foilsithe / Cruthaithe 2020

Journal article

20

Structural dynamics of the ubiquitin specific protease UPS30 in complex with a cyanopyrrolidine-containing covalent inhibitor de réir O’Brien, DP, Jones, HBL, Shi, Y, Guenther, F, Vendrell, I, Viner, R, Brennan, PE, Mead, E, Zarganes-Tzitzikas, T, Davis, JB, Pinto-Fernández, A, England, KS, Murphy, EJ, Turnbull, AP, Kessler, BM

Foilsithe / Cruthaithe 2024

Internet publication

Integrative proximal-ubiquitomics profiling for deubiquitinase and E3 ligase substrate discovery applied to USP30 de réir Damianou, A, Jones, H, Grigoriou, A, Vendrell, I, Davis, S, Kessler, B

Modulation of proteostasis counteracts oxidative stress and affects DNA base excision repair capacity in ATM-deficient cells de réir Poletto, M, Yang, D, Fletcher, S, Vendrell, I, Fischer, R, Legrand, A, Dianov, G

Data-independent acquisition proteomics of cerebrospinal fluid implicates endoplasmic reticulum and inflammatory mechanisms in amyotrophic lateral sclerosis de réir Dellar, ER, Vendrell, I, Talbot, K, Kessler, B, Fischer, R, Turner, MR, Thompson, AG

RASSF1A is required for the maintenance of nuclear actin levels de réir Chatzifrangkeskou, M, Pefani, D, Eyres, M, Vendrell, I, Fischer, R, Pankova, D, O'Neill, E

RASSF1A controls tissue stiffness and cancer stem‐like cells in lung adenocarcinoma de réir Pankova, D, Jiang, Y, Chatzifrangkeskou, M, Vendrell, I, Buzzelli, J, Ryan, A, Brown, C, O'Neill, E

SPRTN protease-cleaved MRE11 decreases DNA repair and radiosensitises cancer cells de réir Na, J, Newman, J, Then, CK, Syed, J, Vendrell, I, Torrecilla, I, Ellermann, S, Ramadan, K, Fischer, R, Kiltie, A

p97/VCP inhibition causes excessive MRE11-dependent DNA end resection promoting cell killing after ionizing radiation de réir Kilgas, S, Singh, AN, Paillas, S, Then, C-K, Torrecilla, I, Nicholson, J, Browning, L, Vendrell, I, Konietzny, R, Kiltie, AE, Ramadan, K

BLM and BRCA1-BARD1 coordinate complementary mechanisms of joint DNA molecule resolution de réir Tsukada, K, Jones, SE, Bannister, J, Durin, M-A, Vendrell, I, Fawkes, M, Fischer, R, Kessler, BM, Chapman, JR, Blackford, AN

Disease-associated KBTBD4 mutations in medulloblastoma elicit neomorphic ubiquitylation activity to promote CoREST degradation de réir Chen, Z, Ioris, RM, Richardson, S, Van Ess, AN, Vendrell, I, Kessler, BM, Buffa, FM, Busino, L, Clifford, SC, Bullock, AN, D'Angiolella, V

Oncogenic mutations of KRAS modulate its turnover by the CUL3/LZTR1 E3 ligase complex de réir Damianou, A, Liang, Z, Lassen, F, Vendrell, I, Vere, G, Hester, S, Charles, PD, Pinto-Fernandez, A, Santos, A, Fischer, R, Kessler, BM

Tumor imaging using radiolabelled matrix metalloproteinase-activated anthrax proteins de réir Xavier, M, Liu, S, Bugge, T, Baguna-Torres, J, Mosley, M, Hopkins, S, Allen, P, Berridge, G, Vendrell, I, Fischer, R, Kersemans, V, Smart, S, Leppla, S, Cornelissen, B

Cyclin F–EXO1 axis controls cell cycle–dependent execution of double-strand break repair de réir Yang, H, Fouad, S, Smith, P, Bae, EY, Ji, Y, Lan, X, Van Ess, A, Buffa, FM, Fischer, R, Vendrell, I, Kessler, BM, D’Angiolella, V

USP18 is an essential regulator of muscle cell differentiation and maturation de réir Olie, CS, Pinto-Fernández, A, Damianou, A, Vendrell, I, Mei, H, den Hamer, B, van der Wal, E, de Greef, JC, Raz, V, Kessler, BM

Structural premise of selective deubiquitinase USP30 inhibition by small-molecule benzosulfonamides de réir O’Brien, DP, Jones, HBL, Guenther, F, Murphy, EJ, England, KS, Vendrell, I, Anderson, M, Brennan, PE, Davis, JB, Pinto-Fernández, A, Turnbull, AP, Kessler, BM

E2F1 proteolysis via SCF-cyclin F underlies synthetic lethality between cyclin F loss and Chk1 inhibition de réir Burdova, K, Yang, H, Faedda, R, Hume, S, Chauhan, J, Ebner, D, Kessler, B, Vendrell, I, Drewry, D, Wells, C, Hatch, S, Dianov, G, Buffa, F, D'Angiolella, V

SPRTN protease and checkpoint kinase 1 cross-activation loop safeguards DNA replication de réir Halder, S, Torrecilla, I, Burkhalter, MD, Popović, M, Fielden, J, Vaz, B, Oehler, J, Pilger, D, Lessel, D, Wiseman, K, Singh, AN, Vendrell, I, Fischer, R, Philipp, M, Ramadan, K

TEX264 coordinates p97- and SPRTN-mediated resolution of topoisomerase 1-DNA adducts de réir Fielden, J, Wiseman, K, Torrecilla, I, Li, S, Hume, S, Chiang, SC, Ruggiano, A, Singh, AN, Freire, R, Hassanieh, S, Domingo, E, Vendrell, I, Fischer, R, Kessler, BM, Maughan, TS, El-Khamisy, SF, Ramadan, K

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