DNA-Related Pathways Defective in Human Premature Aging by Vilhelm A. Bohr

Get full text

Urolithin A and nicotinamide riboside differentially regulate innate immune defenses and metabolism in human microglial cells by Helena Borland Madsen, Claudia Navarro, Emilie Gasparini, Jae-Hyeon Park, Zhiquan Li, Deborah L. Croteau, Deborah L. Croteau, Vilhelm A. Bohr, Vilhelm A. Bohr

Get full text

Cytosolic Self-DNA—A Potential Source of Chronic Inflammation in Aging by Mansour Akbari, Daryl P. Shanley, Vilhelm A. Bohr, Lene Juel Rasmussen

Get full text

Heterochromatin: an epigenetic point of view in aging by Jong-Hyuk Lee, Edward W. Kim, Deborah L. Croteau, Vilhelm A. Bohr

Get full text

Mechanism of Werner DNA helicase: POT1 and RPA stimulates WRN to unwind beyond gaps in the translocating strand. by Byungchan Ahn, Jae Wan Lee, Hana Jung, Gad Beck, Vilhelm A Bohr

Get full text

Nucleolin inhibits G4 oligonucleotide unwinding by Werner helicase. by Fred E Indig, Ivana Rybanska, Parimal Karmakar, Chakravarty Devulapalli, Haiqing Fu, France Carrier, Vilhelm A Bohr

Get full text

WRN regulates pathway choice between classical and alternative non-homologous end joining by Raghavendra A. Shamanna, Huiming Lu, Jessica K. de Freitas, Jane Tian, Deborah L. Croteau, Vilhelm A. Bohr

Get full text

RECQL4 requires PARP1 for recruitment to DNA damage, and PARG dePARylation facilitates its associated role in end joining by Mansoor Hussain, Prabhat Khadka, Komal Pekhale, Tomasz Kulikowicz, Samuel Gray, Alfred May, Deborah L. Croteau, Vilhelm A. Bohr

Get full text

Enzymatic activities and DNA substrate specificity of Mycobacterium tuberculosis DNA helicase XPB. by Seetha V Balasingham, Ephrem Debebe Zegeye, Håvard Homberset, Marie L Rossi, Jon K Laerdahl, Vilhelm A Bohr, Tone Tønjum

Get full text

RecQ dysfunction contributes to social and depressive-like behavior and affects aldolase activity in mice by Yujun Hou, Jae-Hyeon Park, Xiuli Dan, Xixia Chu, Beimeng Yang, Mansoor Hussain, Deborah L. Croteau, Vilhelm A. Bohr

Get full text

The DNA repair enzyme, aprataxin, plays a role in innate immune signaling by Helena B. Madsen, Louise I. Pease, Rebekah-Louise Scanlan, Mansour Akbari, Lene J. Rasmussen, Daryl P. Shanley, Vilhelm A. Bohr

Get full text

Age-related disease association of endogenous γ-H2AX foci in mononuclear cells derived from leukapheresis. by Shepherd H Schurman, Christopher A Dunn, Rebecca Greaves, Binbing Yu, Luigi Ferrucci, Deborah L Croteau, Michael M Seidman, Vilhelm A Bohr

Get full text

Markers of Mitochondrial Function and DNA Repair Associated with Physical Function in Centenarians by Ines Sanchez-Roman, Beatriz Ferrando, Camilla Myrup Holst, Jonas Mengel-From, Signe Hoei Rasmussen, Mikael Thinggaard, Vilhelm A. Bohr, Kaare Christensen, Tinna Stevnsner

Get full text

Acquired Localized Cutis Laxa due to Increased Elastin Turnover by Rie Harboe Nygaard, Scott Maynard, Peter Schjerling, Michael Kjaer, Klaus Qvortrup, Vilhelm A. Bohr, Lene J. Rasmussen, Gregor B.E. Jemec, Michael Heidenheim

Get full text

Nicotinamide adenine dinucleotide supplementation drives gut microbiota variation in Alzheimer’s mouse model by Xixia Chu, Yujun Hou, Yujun Hou, Qiong Meng, Deborah L. Croteau, Deborah L. Croteau, Yong Wei, Supriyo De, Kevin G. Becker, Vilhelm A. Bohr

Get full text

NAD+ augmentation with nicotinamide riboside improves lymphoid potential of Atm −/− and old mice HSCs by Le Zong, Mayuri Tanaka-Yano, Bongsoo Park, Hagai Yanai, Ferda T. Turhan, Deborah L. Croteau, Jane Tian, Evandro F. Fang, Vilhelm A. Bohr, Isabel Beerman

Get full text

A high-throughput screen to identify novel small molecule inhibitors of the Werner Syndrome Helicase-Nuclease (WRN). by Joshua A Sommers, Tomasz Kulikowicz, Deborah L Croteau, Thomas Dexheimer, Dorjbal Dorjsuren, Ajit Jadhav, David J Maloney, Anton Simeonov, Vilhelm A Bohr, Robert M Brosh

Get full text

Nicotinamide riboside modulates the reactive species interactome, bioenergetic status and proteomic landscape in a brain-region-specific manner by Alejandro Marmolejo-Garza, Laurent Chatre, Deborah L. Croteau, Alejandro Herron-Bedoya, Minh Danh Anh Luu, Benoit Bernay, Julien Pontin, Vilhelm A. Bohr, Erik Boddeke, Amalia M. Dolga

Get full text

Short-term NAD+ supplementation prevents hearing loss in mouse models of Cockayne syndrome by Mustafa N. Okur, Beatrice Mao, Risako Kimura, Scott Haraczy, Tracy Fitzgerald, Kamren Edwards-Hollingsworth, Jane Tian, Wasif Osmani, Deborah L. Croteau, Matthew W. Kelley, Vilhelm A. Bohr

Get full text

JNK Phosphorylates SIRT6 to Stimulate DNA Double-Strand Break Repair in Response to Oxidative Stress by Recruiting PARP1 to DNA Breaks by Michael Van Meter, Matthew Simon, Gregory Tombline, Alfred May, Timothy D. Morello, Basil P. Hubbard, Katie Bredbenner, Rosa Park, David A. Sinclair, Vilhelm A. Bohr, Vera Gorbunova, Andrei Seluanov

Get full text