T-cell receptors binding orientation over peptide/MHC class I is driven by long-range interactions. by Mathias Ferber, Vincent Zoete, Olivier Michielin

Get full text

Educational Tools to Introduce Computer-Aided Drug Design to Students and to the Public at Large by Antoine Daina, Marie-Claude Blatter, Vivienne Baillie Gerritsen, Vincent Zoete

Get full text

Distinct OGT-Binding Sites Promote HCF-1 Cleavage. by Tanja Bhuiyan, Patrice Waridel, Vaibhav Kapuria, Vincent Zoete, Winship Herr

Get full text

Both APRIL and antibody-fragment-based CAR T cells for myeloma induce BCMA downmodulation by trogocytosis and internalization by David Gfeller, Benita Wolf, Caroline Arber, Vincent Zoete, Nicolas Camviel, Giancarlo Croce

Get full text

The SwissSimilarity 2021 Web Tool: Novel Chemical Libraries and Additional Methods for an Enhanced Ligand-Based Virtual Screening Experience by Maiia E. Bragina, Antoine Daina, Marta A. S. Perez, Olivier Michielin, Vincent Zoete

Get full text

Swiss-PO: a new tool to analyze the impact of mutations on protein three-dimensional structures for precision oncology by Fanny S. Krebs, Vincent Zoete, Maxence Trottet, Timothée Pouchon, Christophe Bovigny, Olivier Michielin

Get full text

The caveolin-binding motif of the pathogen-related yeast protein Pry1, a member of the CAP protein superfamily, is required for in vivo export of cholesteryl acetate by Vineet Choudhary, Rabih Darwiche, David Gfeller, Vincent Zoete, Olivier Michielin, Roger Schneiter

Get full text

Model structure of human APOBEC3G. by Kun-Lin Zhang, Bastien Mangeat, Millan Ortiz, Vincent Zoete, Didier Trono, Amalio Telenti, Olivier Michielin

Get full text

Monoubiquitination and activity of the paracaspase MALT1 requires glutamate 549 in the dimerization interface. by Katrin Cabalzar, Christiane Pelzer, Annette Wolf, Georg Lenz, Justyna Iwaszkiewicz, Vincent Zoete, Stephan Hailfinger, Margot Thome

Get full text

Structure-based prediction of BRAF mutation classes using machine-learning approaches by Fanny S. Krebs, Christian Britschgi, Sylvain Pradervand, Rita Achermann, Petros Tsantoulis, Simon Haefliger, Andreas Wicki, Olivier Michielin, Vincent Zoete

Get full text

Prediction of cross-recognition of peptide-HLA A2 by Melan-A-specific cytotoxic T lymphocytes using three-dimensional quantitative structure-activity relationships. by Theres Fagerberg, Vincent Zoete, Sebastien Viatte, Petra Baumgaertner, Pedro M Alves, Pedro Romero, Daniel E Speiser, Olivier Michielin

Get full text

The Peroxisomal Enzyme L-PBE Is Required to Prevent the Dietary Toxicity of Medium-Chain Fatty Acids by Jun Ding, Ursula Loizides-Mangold, Gianpaolo Rando, Vincent Zoete, Olivier Michielin, Janardan K. Reddy, Walter Wahli, Howard Riezman, Bernard Thorens

Get full text

Trametinib Induces the Stabilization of a Dual <i>GNAQ</i> p.Gly48Leu- and <i>FGFR4</i> p.Cys172Gly-Mutated Uveal Melanoma. The Role of Molecular Modelling in Personalized Oncology by Fanny S. Krebs, Camille Gérard, Alexandre Wicky, Veronica Aedo-Lopez, Edoardo Missiaglia, Bettina Bisig, Mounir Trimech, Olivier Michielin, Krisztian Homicsko, Vincent Zoete

Get full text

Response and Resistance to Trametinib in MAP2K1-Mutant Triple-Negative Melanoma by Fanny Seraphine Krebs, Bianca Moura, Edoardo Missiaglia, Veronica Aedo-Lopez, Olivier Michielin, Petros Tsantoulis, Bettina Bisig, Mounir Trimech, Vincent Zoete, Krisztian Homicsko

Get full text

VEGFR-2 redirected CAR-T cells are functionally impaired by soluble VEGF-A competition for receptor binding by George Coukos, Evripidis Lanitis, Melita Irving, Paris Kosti, Catherine Ronet, Elisabetta Cribioli, Giorgia Rota, Aodrenn Spill, Patrick Reichenbach, Vincent Zoete, Denarda Dangaj Laniti

Get full text

Design of short peptides to block BTLA/HVEM interactions for promoting anticancer T-cell responses. by Marta Spodzieja, Sławomir Lach, Justyna Iwaszkiewicz, Valérie Cesson, Katarzyna Kalejta, Daniel Olive, Olivier Michielin, Daniel E Speiser, Vincent Zoete, Laurent Derré, Sylwia Rodziewicz-Motowidło

Get full text

Identification of human IKK-2 inhibitors of natural origin (part I): modeling of the IKK-2 kinase domain, virtual screening and activity assays. by Esther Sala, Laura Guasch, Justyna Iwaszkiewicz, Miquel Mulero, Maria-Josepa Salvadó, Montserrat Pinent, Vincent Zoete, Aurélien Grosdidier, Santiago Garcia-Vallvé, Olivier Michielin, Gerard Pujadas

Get full text

Structure-based optimization of type III indoleamine 2,3-dioxygenase 1 (IDO1) inhibitors by Ute F. Röhrig, Somi Reddy Majjigapu, Pierre Vogel, Aline Reynaud, Florence Pojer, Nahzli Dilek, Patrick Reichenbach, Kelly Ascenção, Melita Irving, George Coukos, Olivier Michielin, Vincent Zoete

Get full text

Deciphering the Mechanisms of Improved Immunogenicity of Hypochlorous Acid-Treated Antigens in Anti-Cancer Dendritic Cell-Based Vaccines by Michele Graciotti, Fabio Marino, HuiSong Pak, Petra Baumgaertner, Anne-Christine Thierry, Johanna Chiffelle, Marta A. S. Perez, Vincent Zoete, Alexandre Harari, Michal Bassani-Sternberg, Lana E. Kandalaft

Get full text

Herpes simplex encephalitis in adult patients with MASP-2 deficiency. by Stéphanie Bibert, Jocelyne Piret, Mathieu Quinodoz, Emilie Collinet, Vincent Zoete, Olivier Michielin, Rafik Menasria, Pascal Meylan, Titus Bihl, Véronique Erard, Florence Fellmann, Carlo Rivolta, Guy Boivin, Pierre-Yves Bochud

Get full text