The Orexin-A/OX1R System Induces Cell Death in Pancreatic Cancer Cells Resistant to Gemcitabine and Nab-Paclitaxel Treatment by Thierry Voisin, Pascal Nicole, Valérie Gratio, Anaïs Chassac, Dounia Mansour, Vinciane Rebours, Vinciane Rebours, Anne Couvelard, Anne Couvelard, Alain Couvineau

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The Anti-tumoral Properties of Orexin/Hypocretin Hypothalamic Neuropeptides: An Unexpected Therapeutic Role by Alain Couvineau, Stéphanie Dayot, Pascal Nicole, Valérie Gratio, Vinciane Rebours, Anne Couvelard, Thierry Voisin

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Hypoxia pathways and cellular stress activate pancreatic stellate cells: development of an organotypic culture model of thick slices of normal human pancreas. by Vinciane Rebours, Miguel Albuquerque, Alain Sauvanet, Philippe Ruszniewski, Philippe Lévy, Valérie Paradis, Pierre Bedossa, Anne Couvelard

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Fatal Bile Duct Necrosis: A Rare Complication of Transcatheter Arterial Chemoembolization in a Patient with Endocrine Hepatic Metastasis by Anne-Laure Pelletier, Pascal Hammel, Magali Zappa, Pierre Bedossa, Vinciane Rebours, Olivia Hentic, Frédérique Maire, Philippe Levy, Philippe Ruszniewski

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Role of the fatty pancreatic infiltration in pancreatic oncogenesis by Sonia Frendi, Chloé Martineau, Hélène Cazier, Rémy Nicolle, Anaïs Chassac, Miguel Albuquerque, Jérôme Raffenne, Julie Le Faouder, Valérie Paradis, Jérôme Cros, Anne Couvelard, Vinciane Rebours

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CT-Based Radiomics Analysis to Predict Malignancy in Patients with Intraductal Papillary Mucinous Neoplasm (IPMN) of the Pancreas by David Tobaly, Joao Santinha, Riccardo Sartoris, Marco Dioguardi Burgio, Celso Matos, Jérôme Cros, Anne Couvelard, Vinciane Rebours, Alain Sauvanet, Maxime Ronot, Nikolaos Papanikolaou, Valérie Vilgrain

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Expanding ACMG variant classification guidelines into a general framework by Emmanuelle Masson, Wen-Bin Zou, Emmanuelle Génin, David N. Cooper, Gerald Le Gac, Yann Fichou, Na Pu, Vinciane Rebours, Claude Férec, Zhuan Liao, Jian-Min Chen

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Natural history of SPINK1 germline mutation related-pancreatitis by Nelly Muller, Ioannis Sarantitis, Marie Rouanet, Louis de Mestier, Christopher Halloran, William Greenhalf, Claude Férec, Emmanuelle Masson, Philippe Ruszniewski, Philippe Lévy, John Neoptolemos, Louis Buscail, Vinciane Rebours

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Efficacy and tolerance of LV5FU2-carboplatin chemotherapy in patients with advanced pancreatic ductal adenocarcinoma after failure of standard regimens by Thomas Chaigneau, Lina Aguilera Munoz, Caroline Oger, Clémence Gourdeau, Olivia Hentic, Lucie Laurent, Nelly Muller, Marco Dioguardi Burgio, Marie-Pauline Gagaille, Philippe Lévy, Vinciane Rebours, Pascal Hammel, Louis de Mestier

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Pancreatic Ductal Adenocarcinoma Arising in Young and Old Patients Displays Similar Molecular Features by Jérôme Raffenne, Fernando A. Martin, Rémy Nicolle, Marina Konta, Yuna Blum, Jérôme Torrisani, Francesco Puleo, Jean Baptiste Bachet, Magali Svrcek, Armel Bardier-Dupas, Jean Francois Emile, Peter Demetter, Miroslav Radman, Jean Luc Van Laethem, Pascal Hammel, Vinciane Rebours, Valérie Paradis, Anne Couvelard, Jérôme Cros

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Pacpaint: a histology-based deep learning model uncovers the extensive intratumor molecular heterogeneity of pancreatic adenocarcinoma by Charlie Saillard, Flore Delecourt, Benoit Schmauch, Olivier Moindrot, Magali Svrcek, Armelle Bardier-Dupas, Jean Francois Emile, Mira Ayadi, Vinciane Rebours, Louis de Mestier, Pascal Hammel, Cindy Neuzillet, Jean Baptiste Bachet, Juan Iovanna, Nelson Dusetti, Yuna Blum, Magali Richard, Yasmina Kermezli, Valerie Paradis, Mikhail Zaslavskiy, Pierre Courtiol, Aurelie Kamoun, Remy Nicolle, Jerome Cros

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Acinar-to-Ductal Metaplasia Induced by Transforming Growth Factor Beta Facilitates KRASG12D-driven Pancreatic TumorigenesisSummary by Nicolas Chuvin, David F. Vincent, Roxane M. Pommier, Lindsay B. Alcaraz, Johann Gout, Cassandre Caligaris, Karam Yacoub, Victoire Cardot, Elodie Roger, Bastien Kaniewski, Sylvie Martel, Celia Cintas, Sophie Goddard-Léon, Amélie Colombe, Julie Valantin, Nicolas Gadot, Emilie Servoz, Jennifer Morton, Isabelle Goddard, Anne Couvelard, Vinciane Rebours, Julie Guillermet, Owen J. Sansom, Isabelle Treilleux, Ulrich Valcourt, Stéphanie Sentis, Pierre Dubus, Laurent Bartholin

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