The Current State of Molecular Testing in the BRAF-Mutated Melanoma Landscape by Irene Vanni, Irene Vanni, Enrica Teresa Tanda, Francesco Spagnolo, Virginia Andreotti, Virginia Andreotti, William Bruno, William Bruno, Paola Ghiorzo, Paola Ghiorzo

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Current State of Target Treatment in BRAF Mutated Melanoma by Enrica Teresa Tanda, Irene Vanni, Irene Vanni, Andrea Boutros, Virginia Andreotti, Virginia Andreotti, William Bruno, William Bruno, Paola Ghiorzo, Paola Ghiorzo, Francesco Spagnolo

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Germline <i>POT1</i> Variants: A Critical Perspective on <i>POT1</i> Tumor Predisposition Syndrome by Virginia Andreotti, Irene Vanni, Lorenza Pastorino, Paola Ghiorzo, William Bruno

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Case Report: A BRCA2 Mutation Identified Through Next-Generation Sequencing in a Birt–Hogg–Dubè Syndrome Family by Erika Bandini, Ilaria Cangini, Valentina Arcangeli, Mila Ravegnani, Virginia Andreotti, Virginia Andreotti, Giovanna Prisinzano, Lorenza Pastorino, Lorenza Pastorino, Giovanni Martinelli, Fabio Falcini, Daniele Calistri, Valentina Zampiga, Rita Danesi

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Non-BRAF Mutant Melanoma: Molecular Features and Therapeutical Implications by Irene Vanni, Irene Vanni, Enrica Teresa Tanda, Bruna Dalmasso, Bruna Dalmasso, Lorenza Pastorino, Lorenza Pastorino, Virginia Andreotti, Virginia Andreotti, William Bruno, William Bruno, Andrea Boutros, Francesco Spagnolo, Paola Ghiorzo, Paola Ghiorzo

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The coordinated p53 and estrogen receptor cis-regulation at an FLT1 promoter SNP is specific to genotoxic stress and estrogenic compound. by Yari Ciribilli, Virginia Andreotti, Daniel Menendez, Jan-Stephan Langen, Gilbert Schoenfelder, Michael A Resnick, Alberto Inga

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Functional analysis of a CDKN2A 5'UTR germline variant associated with pancreatic cancer development. by William Bruno, Virginia Andreotti, Alessandra Bisio, Lorenza Pastorino, Giuseppe Fornarini, Stefania Sciallero, Giovanna Bianchi-Scarrà, Alberto Inga, Paola Ghiorzo

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p53 transactivation and the impact of mutations, cofactors and small molecules using a simplified yeast-based screening system. by Virginia Andreotti, Yari Ciribilli, Paola Monti, Alessandra Bisio, Mattia Lion, Jennifer Jordan, Gilberto Fronza, Paola Menichini, Michael A Resnick, Alberto Inga

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Novel Allosteric Mechanism of Dual p53/MDM2 and p53/MDM4 Inhibition by a Small Molecule by Vera V. Grinkevich, Aparna Vema, Karin Fawkner, Natalia Issaeva, Virginia Andreotti, Eleanor R. Dickinson, Elisabeth Hedström, Clemens Spinnler, Alberto Inga, Lars-Gunnar Larsson, Anders Karlén, Margareta Wilhelm, Perdita E. Barran, Andrei L. Okorokov, Galina Selivanova, Joanna E. Zawacka-Pankau

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Ataxia-Telangiectasia Mutated Loss of Heterozygosity in Melanoma by Lorenza Pastorino, Bruna Dalmasso, Eleonora Allavena, Irene Vanni, Filippo Ugolini, Gianna Baroni, Michela Croce, Antonio Guadagno, Francesco Cabiddu, Virginia Andreotti, William Bruno, Gabriele Zoppoli, Lorenzo Ferrando, Enrica Teresa Tanda, Francesco Spagnolo, Chiara Menin, Rosaria Gangemi, Daniela Massi, Paola Ghiorzo

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Clinical Significance of Germline Pathogenic Variants among 51 Cancer Predisposition Genes in an Unselected Cohort of Italian Pancreatic Cancer Patients by Alberto Puccini, Marta Ponzano, Bruna Dalmasso, Irene Vanni, Annalice Gandini, Silvia Puglisi, Roberto Borea, Malvina Cremante, William Bruno, Virginia Andreotti, Eleonora Allavena, Valentino Martelli, Fabio Catalano, Massimiliano Grassi, Maria Laura Iaia, Chiara Pirrone, Alessandro Pastorino, Giuseppe Fornarini, Stefania Sciallero, Paola Ghiorzo, Lorenza Pastorino

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Quality assessment of a clinical next-generation sequencing melanoma panel within the Italian Melanoma Intergroup (IMI) by Irene Vanni, Milena Casula, Lorenza Pastorino, Antonella Manca, Bruna Dalmasso, Virginia Andreotti, Marina Pisano, Maria Colombino, Italian Association for Cancer Research (AIRC) Study Group, Ulrich Pfeffer, Enrica Teresa Tanda, Carla Rozzo, Panagiotis Paliogiannis, Antonio Cossu, Paola Ghiorzo, Giuseppe Palmieri, for the Italian Melanoma Intergroup (IMI)

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Whole-Exome Sequencing and cfDNA Analysis Uncover Genetic Determinants of Melanoma Therapy Response in a Real-World Setting by Irene Vanni, Lorenza Pastorino, Enrica Teresa Tanda, Virginia Andreotti, Bruna Dalmasso, Nicola Solari, Matteo Mascherini, Francesco Cabiddu, Antonio Guadagno, Simona Coco, Eleonora Allavena, William Bruno, Gabriella Pietra, Michela Croce, Rosaria Gangemi, Michele Piana, Gabriele Zoppoli, Lorenzo Ferrando, Francesco Spagnolo, Paola Queirolo, Paola Ghiorzo

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Insights into Genetic Susceptibility to Melanoma by Gene Panel Testing: Potential Pathogenic Variants in <em>ACD</em>, <em>ATM</em>, <em>BAP1</em>, and <em>POT1</em> by Lorenza Pastorino, Virginia Andreotti, Bruna Dalmasso, Irene Vanni, Giulia Ciccarese, Mario Mandalà, Giuseppe Spadola, Maria Antonietta Pizzichetta, Giovanni Ponti, Maria Grazia Tibiletti, Elena Sala, Maurizio Genuardi, Pietro Chiurazzi, Gabriele Maccanti, Siranoush Manoukian, Serena Sestini, Rita Danesi, Valentina Zampiga, Roberta La Starza, Ignazio Stanganelli, Alberto Ballestrero, Luca Mastracci, Federica Grillo, Stefania Sciallero, Federica Cecchi, Enrica Teresa Tanda, Francesco Spagnolo, Paola Queirolo, Italian Melanoma Intergroup (IMI), Alisa M. Goldstein, William Bruno, Paola Ghiorzo

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