High-resolution specificity profiling and off-target prediction for site-specific DNA recombinases by Jeffrey L. Bessen, Lena K. Afeyan, Vlado Dančík, Luke W. Koblan, David B. Thompson, Chas Leichner, Paul A. Clemons, David R. Liu

Get full text

Addendum: High-resolution specificity profiling and off-target prediction for site-specific DNA recombinases by Jeffrey L. Bessen, Lena K. Afeyan, Vlado Dančík, Luke W. Koblan, David B. Thompson, Chas Leichner, Paul A. Clemons, David R. Liu

Get full text

Knowledge Beacons: Web services for data harvesting of distributed biomedical knowledge. by Lance M Hannestad, Vlado Dančík, Meera Godden, Imelda W Suen, Kenneth C Huellas-Bruskiewicz, Benjamin M Good, Christopher J Mungall, Richard M Bruskiewich

Get full text

Predicting compound activity from phenotypic profiles and chemical structures by Nikita Moshkov, Tim Becker, Kevin Yang, Peter Horvath, Vlado Dancik, Bridget K. Wagner, Paul A. Clemons, Shantanu Singh, Anne E. Carpenter, Juan C. Caicedo

Get full text

Quantitative-proteomic comparison of alpha and Beta cells to uncover novel targets for lineage reprogramming. by Amit Choudhary, Kaihui Hu He, Philipp Mertins, Namrata D Udeshi, Vlado Dančík, Dina Fomina-Yadlin, Stefan Kubicek, Paul A Clemons, Stuart L Schreiber, Steven A Carr, Bridget K Wagner

Get full text

A GPX4-dependent cancer cell state underlies the clear-cell morphology and confers sensitivity to ferroptosis by Yilong Zou, Michael J. Palte, Amy A. Deik, Haoxin Li, John K. Eaton, Wenyu Wang, Yuen-Yi Tseng, Rebecca Deasy, Maria Kost-Alimova, Vlado Dančík, Elizaveta S. Leshchiner, Vasanthi S. Viswanathan, Sabina Signoretti, Toni K. Choueiri, Jesse S. Boehm, Bridget K. Wagner, John G. Doench, Clary B. Clish, Paul A. Clemons, Stuart L. Schreiber

Get full text

Biolink Model: A universal schema for knowledge graphs in clinical, biomedical, and translational science by Deepak R. Unni, Sierra A. T. Moxon, Michael Bada, Matthew Brush, Richard Bruskiewich, J. Harry Caufield, Paul A. Clemons, Vlado Dancik, Michel Dumontier, Karamarie Fecho, Gustavo Glusman, Jennifer J. Hadlock, Nomi L. Harris, Arpita Joshi, Tim Putman, Guangrong Qin, Stephen A. Ramsey, Kent A. Shefchek, Harold Solbrig, Karthik Soman, Anne E. Thessen, Melissa A. Haendel, Chris Bizon, Christopher J. Mungall, The Biomedical Data Translator Consortium

Get full text

Progress toward a universal biomedical data translator by Karamarie Fecho, Anne E. Thessen, Sergio E. Baranzini, Chris Bizon, Jennifer J. Hadlock, Sui Huang, Ryan T. Roper, Noel Southall, Casey Ta, Paul B. Watkins, Mark D. Williams, Hao Xu, William Byrd, Vlado Dančík, Marc P. Duby, Michel Dumontier, Gustavo Glusman, Nomi L. Harris, Eugene W. Hinderer, Greg Hyde, Adam Johs, Andrew I. Su, Guangrong Qin, Qian Zhu, The Biomedical Data Translator Consortium

Get full text

Human genetics in rheumatoid arthritis guides a high-throughput drug screen of the CD40 signaling pathway. by Gang Li, Dorothée Diogo, Di Wu, Jim Spoonamore, Vlado Dancik, Lude Franke, Fina Kurreeman, Elizabeth J Rossin, Grant Duclos, Cathy Hartland, Xuezhong Zhou, Kejie Li, Jun Liu, Philip L De Jager, Katherine A Siminovitch, Alexandra Zhernakova, Soumya Raychaudhuri, John Bowes, Steve Eyre, Leonid Padyukov, Peter K Gregersen, Jane Worthington, Rheumatoid Arthritis Consortium International (RACI), Namrata Gupta, Paul A Clemons, Eli Stahl, Nicola Tolliday, Robert M Plenge

Get full text

Niche-Based Screening in Multiple Myeloma Identifies a Kinesin-5 Inhibitor with Improved Selectivity over Hematopoietic Progenitors by Shrikanta Chattopadhyay, Alison L. Stewart, Siddhartha Mukherjee, Cherrie Huang, Kimberly A. Hartwell, Peter G. Miller, Radhika Subramanian, Leigh C. Carmody, Rushdia Z. Yusuf, David B. Sykes, Joshiawa Paulk, Amedeo Vetere, Sonia Vallet, Loredana Santo, Diana D. Cirstea, Teru Hideshima, Vlado Dančík, Max M. Majireck, Mahmud M. Hussain, Shambhavi Singh, Ryan Quiroz, Jonathan Iaconelli, Rakesh Karmacharya, Nicola J. Tolliday, Paul A. Clemons, Malcolm A.S. Moore, Andrew M. Stern, Alykhan F. Shamji, Benjamin L. Ebert, Todd R. Golub, Noopur S. Raje, David T. Scadden, Stuart L. Schreiber

Get full text