PB1863: BRUIN CLL-322: A PHASE 3 OPEN-LABEL, RANDOMIZED STUDY OF FIXED DURATION PIRTOBRUTINIB+VENETOCLAX AND RITUXIMAB VS VENETOCLAX AND RITUXIMAB IN PREVIOUSLY TREATED CLL/SLL (TR... por A. R. Mato, W. G. Wierda, J. M. Pagel, M. S. Davids, P. L. Zinzani, Y. Lu, H. Liu, S. Shahda, C. C. Leow, C. S. Tam, J. A. Woyach, T. A. Eyre

Obter o texto integral

PB1878: CROSS-TRIAL ANALYSIS OF FIXED-DURATION IBRUTINIB (I) PLUS VENETOCLAX (V) VS FLUDARABINE (F), CYCLOPHOSPHAMIDE (C), AND RITUXIMAB (R) AS FIRST-LINE TREATMENT FOR CHRONIC LYM... por J. C. Barrientos, P. M. Barr, A. R. Mato, C. S. Tam, P. Ghia, C. Moreno, N. E. Kay, T. Siddiqi, E. Szafer-Glusman, C. Zhou, L. Neumayr, G. Krigsfeld, W. G. Wierda, T. Shanafelt

Obter o texto integral

P649: A FIRST-IN-HUMAN PHASE 1 TRIAL OF NX-2127, A FIRST-IN-CLASS ORAL BTK DEGRADER WITH IMID-LIKE ACTIVITY, IN PATIENTS WITH RELAPSED AND REFRACTORY B-CELL MALIGNANCIES por A. Mato, A. Danilov, M. R. Patel, M. Tees, I. Flinn, W. Ai, K. Patel, M. Wang, S. M. O’Brien, S. Nandakumar, M. Tan, E. Meredith, M. Gessner, S. Y. Kim, A. Wiestner, W. G. Wierda

Obter o texto integral

S146: VENETOCLAX IN PATIENTS WITH CHRONIC LYMPHOCYTIC LEUKEMIA WITH 17P DELETION: 6-YEAR FOLLOW-UP AND GENOMIC ANALYSES IN A PIVOTAL PHASE 2 TRIAL por S. Stilgenbauer, E. Tausch, A. W. Roberts, M. S. Davids, B. Eichhorst, M. Hallek, P. Hillmen, C. Schneider, S. Böttcher, R. Popovic, M. T. Ghanim, M. Moran, W. J. Sinai, X. Wang, N. Mukherjee, B. Chyla, W. G. Wierda, J. F. Seymour

Obter o texto integral

P640: PIRTOBRUTINIB, A HIGHLY SELECTIVE, NON-COVALENT (REVERSIBLE) BTK INHIBITOR IN COMBINATION WITH VENETOCLAX±RITUXIMAB IN RELAPSED/REFRACTORY CLL: RESULTS FROM THE BRUIN PHASE 1... por L. E. Roeker, A. R. Mato, J. R. Brown, C. C. Coombs, N. N. Shah, W. G. Wierda, M. R. Patel, K. L. Lewis, M. Balbas, J. Zhao, N. C. Ku, J. F. Kherani, D. E. Tsai, B. Nair, C. Y. Cheah

Obter o texto integral

P669: FIXED-DURATION (FD) IBRUTINIB + VENETOCLAX FOR FIRST-LINE TREATMENT OF CHRONIC LYMPHOCYTIC LEUKEMIA (CLL)/SMALL LYMPHOCYTIC LYMPHOMA (SLL): 3-YEAR FOLLOW-UP FROM THE PHASE 2... por C. Moreno, W. G. Wierda, P. M. Barr, T. Siddiqi, J. N. Allan, T. J. Kipps, L. Trentin, R. Jacobs, S. Jackson, A. Tedeschi, S. Opat, R. Bannerji, B. J. Kuss, L. J. Croner, E. Szafer-Glusman, C. Zhou, A. Szoke, J. P. Dean, P. Ghia, C. S. Tam

Obter o texto integral

P369: A PHASE II STUDY OF MINI-HYPER-CVD PLUS VENETOCLAX IN PATIENTS WITH PHILADELPHIA CHROMOSOME-NEGATIVE ACUTE LYMPHOBLASTIC LEUKEMIA por J. Senapati, H. Kantarjian, N. Short, M. Konopleva, F. Ravandi, N. Jain, P. A. Thompson, N. Pemmaraju, W. G. Wierda, G. Borthakur, T. M. Kadia, G. Garcia-Manero, M. Yilmaz, J. Thankachan, M. Zhao, C. Loiselle, M. T. Talley, M. I. Kwari, R. S. Garris, E. J. Jabbour

Obter o texto integral

P666: ACALABRUTINIB ± OBINUTUZUMAB VS OBINUTUZUMAB + CHLORAMBUCIL IN TREATMENT-NAIVE CHRONIC LYMPHOCYTIC LEUKEMIA: 5-YEAR FOLLOW-UP OF ELEVATE-TN por J. P. Sharman, M. Egyed, W. Jurczak, A. Skarbnik, K. Patel, I. W. Flinn, M. Kamdar, T. Munir, R. Walewska, L. M. Fogliatto, Y. Herishanu, V. Banerji, G. Follows, P. Walker, K. Karlsson, P. Ghia, A. Janssens, F. Cymbalista, E. Ferrant, W. G. Wierda, V. Munugalavadla, T. Yu, M. H. Wang, J. A. Woyach

Obter o texto integral

P356: SUBGROUP ANALYSES OF KTE-X19, AN ANTI-CD19 CHIMERIC ANTIGEN RECEPTOR (CAR) T-CELL THERAPY, IN ADULT PATIENTS WITH RELAPSED OR REFRACTORY B-CELL ACUTE LYMPHOBLASTIC LEUKEMIA (... por B. D. Shah, R. D. Cassaday, J. H. Park, R. Houot, O. O. Oluwole, A. C. Logan, N. Boissel, T. Leguay, M. R. Bishop, M. S. Topp, D. Tzachanis, K. M. O’Dwyer, M. L. Arellano, Y. Lin, M. R. Baer, G. J. Schiller, M. Subklewe, M. Abedi, M. C. Minnema, W. G. Wierda, D. J. DeAngelo, P. Stiff, D. Jeyakumar, J. Dong, S. Adhikary, L. Zhou, P. C. Schuberth, B. Kharabi Masouleh, A. Ghobadi

Obter o texto integral

S147: PIRTOBRUTINIB, A HIGHLY SELECTIVE, NON-COVALENT (REVERSIBLE) BTK INHIBITOR IN PREVIOUSLY TREATED CLL/SLL: UPDATED RESULTS FROM THE PHASE 1/2 BRUIN STUDY por A. R. Mato, J. M. Pagel, C. C. Coombs, N. N. Shah, N. Lamanna, T. Munir, E. Lech-Maranda, T. A. Eyre, J. A. Woyach, W. G. Wierda, C. Y. Cheah, J. B. Cohen, L. E. Roeker, M. R. Patel, B. Fakhri, M. A. Barve, C. Tam, D. Lewis, J. N. Gerson, A. J. Alencar, C. Ujjani, I. Flinn, S. Sundaram, S. Ma, D. Jagadeesh, J. Rhodes, J. Taylor, O. Abdel-Wahab, P. Ghia, S. J. Schuster, D. Wang, B. Nair, E. Zhu, D. E. Tsai, M. S. Davids, J. R. Brown, W. Jurczak

Obter o texto integral