Druggable Sterol Metabolizing Enzymes in Infectious Diseases: Cell Targets to Therapeutic Leads by W. David Nes, Minu Chaudhuri, David J. Leaver

Get full text

Cholesterol import fails to prevent catalyst-based inhibition of ergosterol synthesis and cell proliferation of Trypanosoma brucei by Wenxu Zhou, George A.M. Cross, W. David Nes

Get full text

Steroidal Antimetabolites Protect Mice against <i>Trypanosoma brucei</i> by Minu Chaudhuri, Ujjal K. Singha, Boden H. Vanderloop, Anuj Tripathi, W. David Nes

Get full text

Evolutionarily conserved Δ25(27)-olefin ergosterol biosynthesis pathway in the alga Chlamydomonas reinhardtii by Matthew B. Miller, Brad A. Haubrich, Qian Wang, William J. Snell, W. David Nes

Get full text

Enzymatic chokepoints and synergistic drug targets in the sterol biosynthesis pathway of Naegleria fowleri. by Wenxu Zhou, Anjan Debnath, Gareth Jennings, Hye Jee Hahn, Boden H Vanderloop, Minu Chaudhuri, W David Nes, Larissa M Podust

Get full text

CYP51 is an essential drug target for the treatment of primary amoebic meningoencephalitis (PAM). by Anjan Debnath, Claudia M Calvet, Gareth Jennings, Wenxu Zhou, Alexander Aksenov, Madeline R Luth, Ruben Abagyan, W David Nes, James H McKerrow, Larissa M Podust

Get full text

Steroidal antibiotics are antimetabolites of Acanthamoeba steroidogenesis with phylogenetic implications by Wenxu Zhou, Emilio Ramos, Xunlu Zhu, Paxtyn M. Fisher, Medhanie E. Kidane, Boden H. Vanderloop, Crista D. Thomas, Juqiang Yan, Ujjal Singha, Minu Chaudhuri, Michael T. Nagel, W.David Nes

Get full text