Phenotypic and molecular features underlying neurodegeneration of motor neurons derived from spinal and bulbar muscular atrophy patients 由 Marianne Sheila, Gunaseelan Narayanan, Siming Ma, Wai Leong Tam, Josiah Chai, Lawrence W. Stanton

獲取全文

Deep learning based CETSA feature prediction cross multiple cell lines with latent space representation 由 Shenghao Zhao, Xulei Yang, Zeng Zeng, Peisheng Qian, Ziyuan Zhao, Lingyun Dai, Nayana Prabhu, Pär Nordlund, Wai Leong Tam

獲取全文

Mfap4: a promising target for enhanced liver regeneration and chronic liver disease treatment 由 Viktoriia Iakovleva, Anna Wuestefeld, Agnes Bee Leng Ong, Rong Gao, Neslihan Arife Kaya, May Yin Lee, Weiwei Zhai, Wai Leong Tam, Yock Young Dan, Torsten Wuestefeld

獲取全文

<i>miR-7</i> Controls the Dopaminergic/Oligodendroglial Fate through Wnt/β-catenin Signaling Regulation 由 Lavanya Adusumilli, Nicola Facchinello, Cathleen Teh, Giorgia Busolin, Minh TN Le, Henry Yang, Giorgia Beffagna, Stefano Campanaro, Wai Leong Tam, Francesco Argenton, Bing Lim, Vladimir Korzh, Natascia Tiso

獲取全文

Musashi proteins are post-transcriptional regulators of the epithelial-luminal cell state 由 Yarden Katz, Feifei Li, Nicole J Lambert, Ethan S Sokol, Wai-Leong Tam, Albert W Cheng, Edoardo M Airoldi, Christopher J Lengner, Piyush B Gupta, Zhengquan Yu, Rudolf Jaenisch, Christopher B Burge

獲取全文

Signalling inhibition by ponatinib disrupts productive alternative lengthening of telomeres (ALT) 由 Frances Karla Kusuma, Aishvaryaa Prabhu, Galen Tieo, Syed Moiz Ahmed, Pushkar Dakle, Wai Khang Yong, Elina Pathak, Vikas Madan, Yan Yi Jiang, Wai Leong Tam, Dennis Kappei, Peter Dröge, H. Phillip Koeffler, Maya Jeitany

獲取全文

Robust delivery of RIG‐I agonists using extracellular vesicles for anti‐cancer immunotherapy 由 Boya Peng, Trinh Mai Nguyen, Migara Kavishka Jayasinghe, Chang Gao, Thach Tuan Pham, Luyen Tien Vu, Eric Yew Meng Yeo, Gracemary Yap, Lingzhi Wang, Boon Cher Goh, Wai Leong Tam, Dahai Luo, Minh TN Le

獲取全文

Customised design of antisense oligonucleotides targeting EGFR driver mutants for personalised treatment of non-small cell lung cancerResearch in context 由 Trinh T.T. Tran, Cao Dai Phung, Brendon Z.J. Yeo, Rebecca C. Prajogo, Migara K. Jayasinghe, Ju Yuan, Daniel S.W. Tan, Eric Y.M. Yeo, Boon Cher Goh, Wai Leong Tam, Minh T.N. Le

獲取全文

Author Correction: The effect of inhibition of receptor tyrosine kinase AXL on DNA damage response in ovarian cancer 由 Xun Hui Yeo, Vignesh Sundararajan, Zhengwei Wu, Zi Jin Cheryl Phua, Yin Ying Ho, Kai Lay Esther Peh, Yi-Chia Chiu, Tuan Zea Tan, Dennis Kappei, Ying Swan Ho, David Shao Peng Tan, Wai Leong Tam, Ruby Yun-Ju Huang

獲取全文

The effect of inhibition of receptor tyrosine kinase AXL on DNA damage response in ovarian cancer 由 Xun Hui Yeo, Vignesh Sundararajan, Zhengwei Wu, Zi Jin Cheryl Phua, Yin Ying Ho, Kai Lay Esther Peh, Yi-Chia Chiu, Tuan Zea Tan, Dennis Kappei, Ying Swan Ho, David Shao Peng Tan, Wai Leong Tam, Ruby Yun-Ju Huang

獲取全文

B-MYB is essential for normal cell cycle progression and chromosomal stability of embryonic stem cells. 由 Kirill V Tarasov, Yelena S Tarasova, Wai Leong Tam, Daniel R Riordon, Steven T Elliott, Gabriela Kania, Jinliang Li, Satoshi Yamanaka, David G Crider, Gianluca Testa, Ronald A Li, Bing Lim, Colin L Stewart, Yie Liu, Jennifer E Van Eyk, Robert P Wersto, Anna M Wobus, Kenneth R Boheler

獲取全文

PARP4 interacts with hnRNPM to regulate splicing during lung cancer progression 由 Yi Fei Lee, Cheryl Zi Jin Phua, Ju Yuan, Bin Zhang, May Yin Lee, Srinivasaraghavan Kannan, Yui Hei Jasper Chiu, Casslynn Wei Qian Koh, Choon Kong Yap, Edwin Kok Hao Lim, Jianbin Chen, Yuhua Lim, Jane Jia Hui Lee, Anders Jacobsen Skanderup, Zhenxun Wang, Weiwei Zhai, Nguan Soon Tan, Chandra S. Verma, Yvonne Tay, Daniel Shao Weng Tan, Wai Leong Tam

獲取全文

Deficiency of the splicing factor RBM10 limits EGFR inhibitor response in EGFR-mutant lung cancer 由 Shigeki Nanjo, Wei Wu, Niki Karachaliou, Collin M. Blakely, Junji Suzuki, Yu-Ting Chou, Siraj M. Ali, D. Lucas Kerr, Victor R. Olivas, Jonathan Shue, Julia Rotow, Manasi K. Mayekar, Franziska Haderk, Nilanjana Chatterjee, Anatoly Urisman, Jia Chi Yeo, Anders J. Skanderup, Aaron C. Tan, Wai Leong Tam, Oscar Arrieta, Kazuyoshi Hosomichi, Akihiro Nishiyama, Seiji Yano, Yuriy Kirichok, Daniel S.W. Tan, Rafael Rosell, Ross A Okimoto, Trever G. Bivona

獲取全文

Tumour-initiating cell-specific miR-1246 and miR-1290 expression converge to promote non-small cell lung cancer progression 由 Wen Cai Zhang, Tan Min Chin, Henry Yang, Min En Nga, Declan Patrick Lunny, Edwin Kok Hao Lim, Li Li Sun, Yin Huei Pang, Yi Ning Leow, Shanneen Rossellini Y Malusay, Priscilla Xin Hui Lim, Jeravan Zili Lee, Benedict Jian Wei Tan, Ng Shyh-Chang, Elaine Hsuen Lim, Wan Teck Lim, Daniel Shao Weng Tan, Eng Huat Tan, Bee Choo Tai, Ross Andrew Soo, Wai Leong Tam, Bing Lim

獲取全文

Multimodal molecular landscape of response to Y90-resin microsphere radioembolization followed by nivolumab for advanced hepatocellular carcinoma 由 David Tai, Fei Yao, Joycelyn Lee, Su Pin Choo, Joe Yeong, Jeffrey Chun Tatt Lim, Han Chong Toh, Xinru Lim, Jiangfeng Ye, Denise Goh, Tony Kiat-Hon Lim, Mai Chan Lau, Timothy Wai Ho Shuen, Weiwei Zhai, Jia Qi Lim, Lawrence Cheung, Neslihan Arife Kaya, Cheryl Zi Jin Phua, Felicia Yu Ting Wee, Craig Ryan Joseph, Zhen Wei Neo, Kelvin S H Loke, Apoorva Gogna, May Yin Lee, Axel Hilmer, Yun Shen Chan, Wai Leong Tam

獲取全文

Dependency of NELF-E-SLUG-KAT2B epigenetic axis in breast cancer carcinogenesis 由 Jieqiong Zhang, Zhenhua Hu, Hwa Hwa Chung, Yun Tian, Kah Weng Lau, Zheng Ser, Yan Ting Lim, Radoslaw M. Sobota, Hwei Fen Leong, Benjamin Jieming Chen, Clarisse Jingyi Yeo, Shawn Ying Xuan Tan, Jian Kang, Dennis Eng Kiat Tan, Ieng Fong Sou, Urszula Lucja McClurg, Manikandan Lakshmanan, Thamil Selvan Vaiyapuri, Anandhkumar Raju, Esther Sook Miin Wong, Vinay Tergaonkar, Ravisankar Rajarethinam, Elina Pathak, Wai Leong Tam, Ern Yu Tan, Wee-Wei Tee

獲取全文

Elucidating the genomic architecture of Asian EGFR-mutant lung adenocarcinoma through multi-region exome sequencing 由 Rahul Nahar, Weiwei Zhai, Tong Zhang, Angela Takano, Alexis J. Khng, Yin Yeng Lee, Xingliang Liu, Chong Hee Lim, Tina P. T. Koh, Zaw Win Aung, Tony Kiat Hon Lim, Lavanya Veeravalli, Ju Yuan, Audrey S. M. Teo, Cheryl X. Chan, Huay Mei Poh, Ivan M. L. Chua, Audrey Ann Liew, Dawn Ping Xi Lau, Xue Lin Kwang, Chee Keong Toh, Wan-Teck Lim, Bing Lim, Wai Leong Tam, Eng-Huat Tan, Axel M. Hillmer, Daniel S. W. Tan

獲取全文

Domain-specific p53 mutants activate EGFR by distinct mechanisms exposing tissue-independent therapeutic vulnerabilities 由 Teresa Lai Fong Ho, May Yin Lee, Hui Chin Goh, Germaine Yi Ning Ng, Jane Jia Hui Lee, Srinivasaraghavan Kannan, Yan Ting Lim, Tianyun Zhao, Edwin Kok Hao Lim, Cheryl Zi Jin Phua, Yi Fei Lee, Rebecca Yi Xuan Lim, Perry Jun Hao Ng, Ju Yuan, Dedrick Kok Hong Chan, Bettina Lieske, Choon Seng Chong, Kuok Chung Lee, Jeffrey Lum, Wai Kit Cheong, Khay Guan Yeoh, Ker Kan Tan, Radoslaw M. Sobota, Chandra S. Verma, David P. Lane, Wai Leong Tam, Ashok R. Venkitaraman

獲取全文

Intratumoural immune heterogeneity as a hallmark of tumour evolution and progression in hepatocellular carcinoma 由 Phuong H. D. Nguyen, Siming Ma, Cheryl Z. J. Phua, Neslihan A. Kaya, Hannah L. H. Lai, Chun Jye Lim, Jia Qi Lim, Martin Wasser, Liyun Lai, Wai Leong Tam, Tony K. H. Lim, Wei Keat Wan, Tracy Loh, Wei Qiang Leow, Yin Huei Pang, Chung Yip Chan, Ser Yee Lee, Peng Chung Cheow, Han Chong Toh, Florent Ginhoux, Shridhar Iyer, Alfred W. C. Kow, Yock Young Dan, Alexander Chung, Brian K. P. Goh, Salvatore Albani, Pierce K. H. Chow, Weiwei Zhai, Valerie Chew

獲取全文

Author Correction: Intratumoural immune heterogeneity as a hallmark of tumour evolution and progression in hepatocellular carcinoma 由 Phuong H. D. Nguyen, Siming Ma, Cheryl Z. J. Phua, Neslihan A. Kaya, Hannah L. H. Lai, Chun Jye Lim, Jia Qi Lim, Martin Wasser, Liyun Lai, Wai Leong Tam, Tony K. H. Lim, Wei Keat Wan, Tracy Loh, Wei Qiang Leow, Yin Huei Pang, Chung Yip Chan, Ser Yee Lee, Peng Chung Cheow, Han Chong Toh, Florent Ginhoux, Shridhar Iyer, Alfred W. C. Kow, Yock Young Dan, Alexander Chung, Glen K. Bonney, Brian K. P. Goh, Salvatore Albani, Pierce K. H. Chow, Weiwei Zhai, Valerie Chew

獲取全文