Bruce D. Walker
Bruce D. Walker (born 1952) is an American physician and scientist whose infectious disease research has produced many findings regarding HIV/AIDS. He became interested in studying HIV/AIDS after practicing on the front lines of the epidemic in the early 1980s, prior to the identification of HIV as the etiologic agent and prior to the availability of viable treatment options.An infectious disease specialist and researcher, Walker is the founding director of the Ragon Institute of Mass General, MIT, and Harvard. He is also an investigator at Howard Hughes Medical Institute, an adjunct professor at Nelson R. Mandela School of Medicine at the University of KwaZulu-Natal, and a founding co-director of the Africa Health Research Institute, formerly known as KwaZulu-Natal Research Institute for Tuberculosis and HIV (K-RITH).
He played an active role in COVID-19 research, helping found and co-lead the Massachusetts Consortium on Pathogen Readiness (MassCPR) and advance vaccine development with the Ragon Institute.
Walker was named a Fellow of the American Association for the Advancement of Science in 2004. He was elected to the National Academy of Medicine in 2009. Provided by Wikipedia
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Evolution and Diversity of Immune Responses during Acute HIV Infection by Kazer, Samuel W, Walker, Bruce D, Shalek, Alex K
Published 2022
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Translating HIV Sequences into Quantitative Fitness Landscapes Predicts Viral Vulnerabilities for Rational Immunogen Design by Ferguson, Andrew L., Mann, Jaclyn K., Omarjee, Saleha, Ndung'u, Thumbi, Walker, Bruce D., Chakraborty, Arup K., Ferguson, Andrew L.
Published 2016
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The Fitness Landscape of HIV-1 Gag: Advanced Modeling Approaches and Validation of Model Predictions by In Vitro Testing by Mann, Jaclyn K., Barton, John P., Ferguson, Andrew L., Omarjee, Saleha, Walker, Bruce D., Ndung'u, Thumbi, Chakraborty, Arup K
Published 2014
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Rapid, efficient functional characterization and recovery of HIV-specific human CD8+ T cells using microengraving by Varadarajan, Navin, Kwon, Douglas, Law, Kenneth M., Ogunniyi, Adebola Oluwakayode, Anahtar, Melis N., Richter, James M., Walker, Bruce D., Love, John C
Published 2012
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High Avidity CD8+ T Cells Efficiently Eliminate Motile HIV-Infected Targets and Execute a Locally Focused Program of Anti-Viral Function by Foley, Maria Hottelet, Forcier, Talitha L., McAndrew, Elizabeth G., Gonzalez, Michael, Chen, Huabiao, Juelg, Boris, Walker, Bruce D., Irvine, Darrell J
Published 2014
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Profiling human antibody responses by integrated single-cell analysis by Ogunniyi, Adebola Oluwakayode, Politano, Timothy J., Varadarajan, Navin, Landais, Elise, Poignard, Pascal, Walker, Bruce D., Kwon, Douglas S., Love, J. Christopher, Thomas, Brittany Anne
Published 2016
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Effects of thymic selection of the T cell repertoire on HLA-class I associated control of HIV infection by Kosmrlj, Andrej, Read, Elizabeth L., Qi, Ying, Allen, Todd M., Altfeld, Marcus, Deeks, Steven G., Pereyra, Florencia, Carrington, Mary, Walker, Bruce D., Chakraborty, Arup K
Published 2013
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Engineering modular intracellular protein sensor-actuator devices by Monel, Blandine, Beal, Jacob, Clayton, Kiera L, Wroblewska, Liliana, McKeon, AnneMarie, Walker, Bruce D., Siciliano, Velia, DiAndreth, Breanna, Huh, Jin Hang, Weiss, Ron
Published 2018
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Coordinate linkage of HIV evolution reveals regions of immunological vulnerability by Pereyra, Florencia, Miura, Toshiyuki, Allen, Todd M., Altfeld, Marcus, Carrington, Mary, Walker, Bruce D., Dahirel, Vincent, Shekhar, Karthik, Artyomov, Mikita, Talsania, Shiv, Irvine, Darrell J., Chakraborty, Arup K.
Published 2012
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Histone Deacetylase Inhibitors Impair the Elimination of HIV-Infected Cells by Cytotoxic T-Lymphocytes by Jones, Richard Bradley, O'Connor, Rachel, Mueller, Stefanie, Foley, Maria Hottelet, Karel, Dan, Lichterfeld, Mathias, Kovacs, Colin, Ostrowski, Mario A., Trocha, Alicja, Walker, Bruce D., Szeto, Gregory, Irvine, Darrell J
Published 2014
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A Reproducibility-Based Computational Framework Identifies an Inducible, Enhanced Antiviral State in Dendritic Cells from HIV-1 Elite Controllers by Martin-Gayo, Enrique, Cole, Michael B., Ouyang, Zhengyu, Cronin, Jacqueline, Lichterfeld, Mathias, Walker, Bruce D., Yosef, Nir, Yu, Xu G., Kolb, Kellie Elizabeth, Kazer, Samuel Weisgurt, Ordovas-Montanes, Jose Manuel, Shalek, Alexander K
Published 2018
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A Reproducibility-Based Computational Framework Identifies an Inducible, Enhanced Antiviral State in Dendritic Cells from HIV-1 Elite Controllers by Martin-Gayo, Enrique, Ouyang, Zhengyu, Cronin, Jacqueline, Lichterfeld, Mathias, Yosef, Nir, Cole, Michael B., Walker, Bruce D., Yu, Xu G., Kolb, Kellie Elizabeth, Kazer, Samuel Weisgurt, Ordovas-Montanes, Jose Manuel, Shalek, Alexander K
Published 2018
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Virus-driven Inflammation Is Associated With the Development of bNAbs in Spontaneous Controllers of HIV by Dugast, Anne-Sophie, Lofano, Giuseppe, Moore, Sarah, Hoffner, Michelle, Simek, Melissa, Poignard, Pascal, Seaman, Michael, Suscovich, Todd J., Pereyra, Florencia, Walker, Bruce D., Kwon, Douglas S., Keele, Brandon F., Alter, Galit, Arnold, Kelly Benedict, Lauffenburger, Douglas A
Published 2018
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HST.176 Cellular and Molecular Immunology, Fall 2002 by Pillai, Shiv, Anderson, Paul, Auchincloss, Hugh, Balk, Steven, Cherayil, Bobby, Davis, Benjamin, Hafler, David A., Lichtman, Andrew H., Ploegh, Hidde L., Rajewsky, K., 1936-, Schmidt, Emmett Vance, 1952-, Sharpe, Arlene, Sykes, Megan, Andrian, Ulrich von, Walker, Bruce D., 1952-
Published 2002
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Circulating CXCR5[superscript +]CXCR3[superscript +]PD-1[superscript lo] Tfh-like cells in HIV-1 controllers with neutralizing antibody breadth by Martin-Gayo, Enrique, Cronin, Jacqueline, Hickman, Taylor, Ouyang, Zhengyu, Lindqvist, Madelene, Schulze zur Wiesch, Julian, Cubas, Rafael, Porichis, Filippos, van Lunzen, Jan, Haddad, Elias K., Walker, Bruce D., Kaufmann, Daniel E., Lichterfeld, Mathias, Yu, Xu G., Kolb, Kellie Elizabeth, Shalek, Alexander K
Published 2018
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A genome-wide CRISPR screen identifies a restricted set of HIV host dependency factors by Park, Ryan J, Koundakjian, Dylan, Hultquist, Judd F, Lamothe-Molina, Pedro, Monel, Blandine, Schumann, Kathrin, Yu, Haiyan, Krupzcak, Kevin M, Garcia-Beltran, Wilfredo, Piechocka-Trocha, Alicja, Krogan, Nevan J, Marson, Alexander, Hacohen, Nir, Walker, Bruce D, Wang, Tim, Sabatini, David, Lander, Eric Steven
Published 2018
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Temporal effect of HLA-B*57 on viral control during primary HIV-1 infection by Vaidya, Sagar A, Streeck, Hendrik, Beckwith, Noor, Ghebremichael, Musie, Pereyra, Florencia, Addo, Marylyn M., Rychert, Jenna, Routy, Jean-Pierre, Jessen, Heiko, Kelleher, Anthony D, Hecht, Frederick, Sekaly, Rafick-Pierre, Carrington, Mary, Walker, Bruce D, Allen, Todd M., Rosenberg, Eric S, Altfeld, Marcus, Kwon, Douglas
Published 2014
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