Walter J. Koch

Walter J. Koch Walter J. “Wally” Koch (born March 2, 1961) is an American scientist best known for his work with G protein-coupled receptors in the heart and gene therapy approaches to cardiovascular disease. He is currently an Instructor at Duke University, and formerly at Lewis Katz School of Medicine at Temple University where he was the Director of the Center for Translational Medicine, Professor and Chairman of the Department of Pharmacology, and W.W. Smith Chair in Cardiovascular Medicine. In 2013, he co-founded the biotech company, Renovacor. Provided by Wikipedia
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  1. 1
    Nitric Oxide and S-Nitrosylation in Cardiac Regulation: G Protein-Coupled Receptor Kinase-2 and β-Arrestins as Targets

    Nitric Oxide and S-Nitrosylation in Cardiac Regulation: G Protein-Coupled Receptor Kinase-2 and β-Arrestins as Targets by Gizem Kayki-Mutlu, Walter J. Koch

    Published 2021-01-01
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  2. 2
    New Insights in Cardiac β-Adrenergic Signaling During Heart Failure and Aging

    New Insights in Cardiac β-Adrenergic Signaling During Heart Failure and Aging by Claudio de Lucia, Akito Eguchi, Walter J. Koch

    Published 2018-08-01
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  3. 3
    Targeting cardiac beta-adrenergic signaling via GRK2 inhibition for heart failure therapy

    Targeting cardiac beta-adrenergic signaling via GRK2 inhibition for heart failure therapy by Alessandro eCannavo, Daniela eLiccardo, Walter J. Koch

    Published 2013-09-01
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  4. 4
    In Vivo Stimulation of α- and β-Adrenoceptors in Mice Differentially Alters Small RNA Content of Circulating Extracellular Vesicles

    In Vivo Stimulation of α- and β-Adrenoceptors in Mice Differentially Alters Small RNA Content of Circulating Extracellular Vesicles by Jin-Sook Kwon, Eric W. Barr, J. Kurt Chuprun, Walter J. Koch

    Published 2021-05-01
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  5. 5
    Identification and Characterization of Amlexanox as a G Protein-Coupled Receptor Kinase 5 Inhibitor

    Identification and Characterization of Amlexanox as a G Protein-Coupled Receptor Kinase 5 Inhibitor by Kristoff T. Homan, Emily Wu, Alessandro Cannavo, Walter J. Koch, John J. G. Tesmer

    Published 2014-10-01
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  6. 6
    Targeting GRK5 for Treating Chronic Degenerative Diseases

    Targeting GRK5 for Treating Chronic Degenerative Diseases by Federica Marzano, Antonio Rapacciuolo, Nicola Ferrara, Giuseppe Rengo, Walter J. Koch, Alessandro Cannavo

    Published 2021-02-01
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  7. 7
    Sponging Away Cardiac Injury

    Sponging Away Cardiac Injury by Gizem Kayki-Mutlu, PhD, Kimberly M. Ferrero, MS, Walter J. Koch, PhD

    Published 2022-11-01
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  8. 8
    Ethyl Pyruvate Modulates Murine Dendritic Cell Activation and Survival Through Their Immunometabolism

    Ethyl Pyruvate Modulates Murine Dendritic Cell Activation and Survival Through Their Immunometabolism by Marita Chakhtoura, Robert W. Chain, Priscila Y. Sato, Priscila Y. Sato, Connie C. Qiu, Michael H. Lee, Joseph J. Meissler, Joseph J. Meissler, Toby K. Eisenstein, Toby K. Eisenstein, Walter J. Koch, Walter J. Koch, Roberto Caricchio, Stefania Gallucci

    Published 2019-01-01
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  9. 9
    Identification and Comparison of Hyperglycemia-Induced Extracellular Vesicle Transcriptome in Different Mouse Stem Cells

    Identification and Comparison of Hyperglycemia-Induced Extracellular Vesicle Transcriptome in Different Mouse Stem Cells by Grace Huang, Venkata Naga Srikanth Garikipati, Yan Zhou, Cynthia Benedict, Steven R. Houser, Walter J. Koch, Raj Kishore

    Published 2020-09-01
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  10. 10
    Metabolic Reprogramming in HIV-Associated Neurocognitive Disorders

    Metabolic Reprogramming in HIV-Associated Neurocognitive Disorders by Charles N. S. Allen, Sterling P. Arjona, Maryline Santerre, Claudio De Lucia, Walter J. Koch, Bassel E. Sawaya, Bassel E. Sawaya, Bassel E. Sawaya

    Published 2022-03-01
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  11. 11
    Myocardial Strain and Cardiac Output are Preferable Measurements for Cardiac Dysfunction and Can Predict Mortality in Septic Mice

    Myocardial Strain and Cardiac Output are Preferable Measurements for Cardiac Dysfunction and Can Predict Mortality in Septic Mice by Matthew Hoffman, Ioannis D. Kyriazis, Anna M. Lucchese, Claudio de Lucia, Michela Piedepalumbo, Michael Bauer, P. Christian Schulze, Michael J. Bonios, Walter J. Koch, Konstantinos Drosatos

    Published 2019-05-01
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  12. 12
    Tumor necrosis factor-α and lymphotoxin-α mediate myocardial ischemic injury via TNF receptor 1, but are cardioprotective when activating TNF receptor 2.

    Tumor necrosis factor-α and lymphotoxin-α mediate myocardial ischemic injury via TNF receptor 1, but are cardioprotective when activating TNF receptor 2. by Yanqing Zhang, Jianli Zhao, Wayne Bond Lau, Li-Yuan Jiao, Baojiang Liu, Yuexing Yuan, Xiaoliang Wang, Erhe Gao, Walter J Koch, Xin-Liang Ma, Yajing Wang

    Published 2013-01-01
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  13. 13
    Cigarette smoke modulates vascular smooth muscle phenotype: implications for carotid and cerebrovascular disease.

    Cigarette smoke modulates vascular smooth muscle phenotype: implications for carotid and cerebrovascular disease. by Robert M Starke, Muhammad S Ali, Pascal M Jabbour, Stavropoula I Tjoumakaris, Fernando Gonzalez, David M Hasan, Robert H Rosenwasser, Gary K Owens, Walter J Koch, Aaron S Dumont

    Published 2013-01-01
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  14. 14
    Myocardial Ablation of G Protein-Coupled Receptor Kinase 2 (GRK2) Decreases Ischemia/Reperfusion Injury through an Anti-Intrinsic Apoptotic Pathway.

    Myocardial Ablation of G Protein-Coupled Receptor Kinase 2 (GRK2) Decreases Ischemia/Reperfusion Injury through an Anti-Intrinsic Apoptotic Pathway. by Qian Fan, Mai Chen, Lin Zuo, Xiying Shang, Maggie Z Huang, Michele Ciccarelli, Philip Raake, Henriette Brinks, Kurt J Chuprun, Gerald W Dorn, Walter J Koch, Erhe Gao

    Published 2013-01-01
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  15. 15
    Nuclear translocation of cardiac G protein-Coupled Receptor kinase 5 downstream of select Gq-activating hypertrophic ligands is a calmodulin-dependent process.

    Nuclear translocation of cardiac G protein-Coupled Receptor kinase 5 downstream of select Gq-activating hypertrophic ligands is a calmodulin-dependent process. by Jessica I Gold, Jeffrey S Martini, Jonathan Hullmann, Erhe Gao, J Kurt Chuprun, Linda Lee, Douglas G Tilley, Joseph E Rabinowitz, Julie Bossuyt, Donald M Bers, Walter J Koch

    Published 2013-01-01
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  16. 16
    G protein-coupled receptor kinase 2 promotes cardiac hypertrophy.

    G protein-coupled receptor kinase 2 promotes cardiac hypertrophy. by Philipp Schlegel, Julia Reinkober, Eric Meinhardt, Henrike Tscheschner, Erhe Gao, Sarah M Schumacher, Ancai Yuan, Johannes Backs, Patrick Most, Thomas Wieland, Walter J Koch, Hugo A Katus, Philip W Raake

    Published 2017-01-01
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  17. 17
    LIN28a induced metabolic and redox regulation promotes cardiac cell survival in the heart after ischemic injury

    LIN28a induced metabolic and redox regulation promotes cardiac cell survival in the heart after ischemic injury by Antonia Elizabeth Yuko, Vagner Oliveira Carvalho Rigaud, Justin Kurian, Ji H. Lee, Nicole Kasatkin, Michael Behanan, Tao Wang, Anna Maria Luchesse, Sadia Mohsin, Walter J. Koch, Hong Wang, Mohsin Khan

    Published 2021-11-01
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  18. 18
    microRNA in Cardiovascular Aging and Age-Related Cardiovascular Diseases

    microRNA in Cardiovascular Aging and Age-Related Cardiovascular Diseases by Claudio de Lucia, Claudio de Lucia, Klara Komici, Giulia Borghetti, Grazia Daniela Femminella, Leonardo Bencivenga, Alessandro Cannavo, Alessandro Cannavo, Graziamaria Corbi, Nicola Ferrara, Nicola Ferrara, Steven R. Houser, Walter J. Koch, Giuseppe Rengo, Giuseppe Rengo

    Published 2017-06-01
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  19. 19
    Sphingosine Kinases and Sphingosine 1-Phosphate Receptors: Signaling and Actions in the Cardiovascular System

    Sphingosine Kinases and Sphingosine 1-Phosphate Receptors: Signaling and Actions in the Cardiovascular System by Alessandro Cannavo, Alessandro Cannavo, Daniela Liccardo, Daniela Liccardo, Klara Komici, Graziamaria Corbi, Claudio de Lucia, Grazia D. Femminella, Andrea Elia, Leonardo Bencivenga, Nicola Ferrara, Nicola Ferrara, Walter J. Koch, Nazareno Paolocci, Nazareno Paolocci, Giuseppe Rengo, Giuseppe Rengo

    Published 2017-08-01
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  20. 20
    Consequence of the tumor‐associated conversion to cyclin D1b

    Consequence of the tumor‐associated conversion to cyclin D1b by Michael A Augello, Lisa D Berman‐Booty, Richard Carr 3rd, Akihiro Yoshida, Jeffry L Dean, Matthew J Schiewer, Felix Y Feng, Scott A Tomlins, Erhe Gao, Walter J Koch, Jeffrey L Benovic, John Alan Diehl, Karen E Knudsen

    Published 2015-05-01
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