Merkel cell carcinoma and follicular lymphoma: A highly unusual collision tumor by Kran Suknuntha, Kritika Subramanian, Joelle Racchumi, Wayne Tam

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Mutation analysis links angioimmunoblastic T-cell lymphoma to clonal hematopoiesis and smoking by Shuhua Cheng, Wei Zhang, Giorgio Inghirami, Wayne Tam

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Simple deep sequencing-based post-remission MRD surveillance predicts clinical relapse in B-ALL by Shuhua Cheng, Giorgio Inghirami, Shuo Cheng, Wayne Tam

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Myeloid neoplasms with isolated del(5q) and JAK2 V617F mutation: a “grey zone” combination of myelodysplastic and myeloproliferative features? by Valentina F.I. Sangiorgio, Julia T. Geyer, Elizabeth Margolskee, Mustafa Al-Kawaaz, Susan Mathew, Wayne Tam, Attilio Orazi

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Dysregulation of Blimp1 transcriptional repressor unleashes p130Cas/ErbB2 breast cancer invasion by Marianna Sciortino, Maria del Pilar Camacho-Leal, Francesca Orso, Elena Grassi, Andrea Costamagna, Paolo Provero, Wayne Tam, Emilia Turco, Paola Defilippi, Daniela Taverna, Sara Cabodi

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Bone marrow morphology is a strong discriminator between chronic eosinophilic leukemia, not otherwise specified and reactive idiopathic hypereosinophilic syndrome by Sa A. Wang, Robert P. Hasserjian, Wayne Tam, Albert G. Tsai, Julia T. Geyer, Tracy I. George, Kathryn Foucar, Heesun J. Rogers, Eric D. Hsi, Bryan A. Rea, Adam Bagg, Carlos E. Bueso-Ramos, Daniel A. Arber, Srdan Verstovsek, Attilio Orazi

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S235: GENERATION AND APPLICATION OF A LIVING T-CELL LYMPHOMA PATIENT-DERIVED TUMOR XENOGRAFT BIOREPOSITORY by Luca Vincenzo Cappelli, Danilo Fiore, Liu Zhaoqi, Nikita Kotlov, Jude Phillip, Paul Zumbo, Liron Yoffe, Claudia Pignataro, Paola Ghione, Han Xueshuai, Valentina Fragliasso, Gerolama Condorelli, Robin Foà, Joshua Brody, Doron Betel, John Chan, Wayne Tam, David Weinstock, Leandro Cerchietti, Raul Rabadan, Steven Horwitz, Giorgio Inghirami

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Comparison of Multiple Clinical Testing Modalities for Assessment of NPM1-Mutant AML by Amanda Lopez, Sanjay Patel, Julia T. Geyer, Joelle Racchumi, Amy Chadburn, Paul Simonson, Madhu M. Ouseph, Giorgio Inghirami, Nuria Mencia-Trinchant, Monica L. Guzman, Alexandra Gomez-Arteaga, Alexandra Gomez-Arteaga, Sangmin Lee, Pinkal Desai, Ellen K. Ritchie, Gail J. Roboz, Wayne Tam, Michael J. Kluk

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<i>STAT5B</i> mutations in myeloid neoplasms differ by disease subtypes but characterize a subset of chronic myeloid neoplasms with eosinophilia and/or basophilia by C. Cameron Yin, Wayne Tam, Serena M. Walker, Amandeep Kaur, Madhu M. Ouseph, Wei Xie, Olga K.Weinberg, Peng Li, Zhuang Zuo, Mark J. Routbort, Simon Chen, L. Jeffrey Medeiros, Tracy I George, Attilio Orazi, Daniel A. Arber, Adam Bagg, Robert P. Hasserjian, Sa A. Wang

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Co-shared genomic alterations within tumors from patients with both myeloproliferative neoplasms and lymphoma by Johanne M. Holst, Martin B. Pedersen, Marie B. Enemark, Marcus C. Hansen, Patrick R. Noerhave, Trine L. Plesner, Henrik Frederiksen, Michael B. Moeller, Stephen J. Hamilton-Dutoit, Peter Noergaard, Bo K. Mortensen, Hans B. Ommen, Jesper Stentoft, Wayne Tam, Maja Ludvigsen, Wing C. Chan, Nicolai J. Birkbak, Giorgio Inghirami, Francesco d’Amore

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P1205: A LIVING PATIENT-DERIVED BIOREPOSITORY FOSTERING MICROENVIRONMENT DISSECTION IN T-CELL LYMPHOMA by Danilo Fiore, Luca Vincenzo Cappelli, Liu Zhaoqi, Nikita Kotlov, Maria Sorokina, Jude Phillip, Paul Zumbo, Liron Yoffe, Han Xueshuai, Claudia Pignataro, Paola Ghione, Valentina Fragliasso, Gerolama Condorelli, Robin Foà, Joshua Brody, Doron Betel, Wing C Chan, Wayne Tam, Anastasie Nikitina, Aleksander Bagaev, Nathan Fowler, David Weinstock, Leandro Cerchietti, Raul Rabadan, Steve Horwitz, Giorgio Inghirami

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Myeloproliferative and lymphoproliferative malignancies occurring in the same patient: a nationwide discovery cohort by Johanne M. Holst, Trine L. Plesner, Martin B. Pedersen, Henrik Frederiksen, Michael B. Møller, Michael R. Clausen, Marcus C. Hansen, Stephen Jacques Hamilton-Dutoit, Peter Nørgaard, Preben Johansen, Tobias Ramm Eberlein, Bo K. Mortensen, Gustav Mathiasen, Andreas Øvlisen, Rui Wang, Chao Wang, Weiwei Zhang, Hans Beier Ommen, Jesper Stentoft, Maja Ludvigsen, Wayne Tam, Wing C. Chan, Giorgio Inghirami, Francesco d'Amore

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Immunoglobulin somatic hypermutation has clinical impact in DLBCL and potential implications for immune checkpoint blockade and neoantigen-based immunotherapies by Zijun Y. Xu-Monette, Jianyong Li, Yi Xia, Beryl Crossley, Robert D. Bremel, Yi Miao, Min Xiao, Thomas Snyder, Ganiraju C. Manyam, Xiaohong Tan, Hongwei Zhang, Carlo Visco, Alexandar Tzankov, Karen Dybkaer, Govind Bhagat, Wayne Tam, Hua You, Eric D. Hsi, J. Han van Krieken, Jooryung Huh, Maurilio Ponzoni, Andrés J. M. Ferreri, Michael B. Møller, Miguel A. Piris, Jane N. Winter, Jeffrey T. Medeiros, Bing Xu, Yong Li, Ilan Kirsch, Ken H. Young

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DNA mismatch repair defect and intratumor heterogeneous deficiency differently impact immune responses in diffuse large B-cell lymphoma by Zijun Y. Xu-Monette, Cancan Luo, Li Yu, Yong Li, Govind Bhagat, Alexandar Tzankov, Carlo Visco, Xiangshan Fan, Karen Dybkaer, Ali Sakhdari, Nicholas T. Wang, Alyssa F. Yuan, April Chiu, Wayne Tam, Youli Zu, Eric D. Hsi, Anamarija M. Perry, Wenting Song, Dennis O’Malley, Qingyan Au, Harry Nunns, Heounjeong Go, Michael B. Møller, Benjamin M. Parsons, Santiago Montes-Moreno, Maurilio Ponzoni, Andrés J.M. Ferreri, Aliyah R. Sohani, Jeremy S. Abramson, Bing Xu, Ken H. Young

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XPO1 expression worsens the prognosis of unfavorable DLBCL that can be effectively targeted by selinexor in the absence of mutant p53 by Manman Deng, Mingzhi Zhang, Zijun Y. Xu-Monette, Lan V. Pham, Alexandar Tzankov, Carlo Visco, Xiaosheng Fang, Govind Bhagat, Feng Zhu, Karen Dybkaer, April Chiu, Wayne Tam, Youli Zu, Eric D. Hsi, William W. L. Choi, Jooryung Huh, Maurilio Ponzoni, Andrés J. M. Ferreri, Michael B. Møller, Benjamin M. Parsons, J. Han van Krieken, Miguel A. Piris, Jane N. Winter, Fredrick Hagemeister, Lapo Alinari, Yong Li, Michael Andreeff, Bing Xu, Ken H. Young

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Targeting the epichaperome as an effective precision medicine approach in a novel PML-SYK fusion acute myeloid leukemia by Mayumi Sugita, David C. Wilkes, Rohan Bareja, Kenneth W. Eng, Sarah Nataraj, Reyna A. Jimenez-Flores, LunBiao Yan, Jeanne Pauline De Leon, Jaclyn A. Croyle, Justin Kaner, Swathi Merugu, Sahil Sharma, Theresa Y. MacDonald, Zohal Noorzad, Palak Panchal, Danielle Pancirer, Shuhua Cheng, Jenny Z. Xiang, Luke Olson, Koen Van Besien, David S. Rickman, Susan Mathew, Wayne Tam, Mark A. Rubin, Himisha Beltran, Andrea Sboner, Duane C. Hassane, Gabriela Chiosis, Olivier Elemento, Gail J. Roboz, Juan Miguel Mosquera, Monica L. Guzman

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