Inhibition of Aurora-B kinase activity confers antitumor efficacy in preclinical mouse models of early and advanced gastrointestinal neoplasia. by Alferez, D, Goodlad, R, Odedra, R, Sini, P, Crafter, C, Ryan, A, Wedge, SR, Wright, N, Anderson, E, Wilkinson, R

Dual inhibition of VEGFR and EGFR signaling reduces the incidence and size of intestinal adenomas in Apc(Min/+) mice. by Alferez, D, Wilkinson, R, Watkins, J, Poulsom, R, Mandir, N, Wedge, SR, Pyrah, I, Smith, N, Jackson, L, Ryan, A, Goodlad, R

Selective DNA-PKcs inhibition extends the therapeutic index of localized radiotherapy and chemotherapy by Willoughby, CE, Jiang, Y, Thomas, HD, Willmore, E, Kyle, S, Wittner, A, Phillips, N, Zhao, Y, Tudhope, SJ, Prendergast, L, Junge, G, Lourenco, LM, Finlay, MRV, Turner, P, Munck, JM, Griffin, RJ, Rennison, T, Pickles, J, Cano, C, Newell, DR, Reeves, HL, Ryan, AJ, Wedge, SR