Interrogating type 2 diabetes genome-wide association data using a biological pathway-based approach. by Perry, JR, McCarthy, M, Hattersley, A, Zeggini, E, Weedon, M, Frayling, T

Quantitative traits associated with the Type 2 diabetes susceptibility allele in Kir6.2. by Weedon, M, Gloyn, A, Frayling, T, Hattersley, A, Davey Smith, G, Ben-Shlomo, Y

No evidence of association of ENPP1 variants with type 2 diabetes or obesity in a study of 8,089 U.K. Caucasians. by Weedon, M, Shields, B, Hitman, G, Walker, M, McCarthy, M, Hattersley, A, Frayling, T

Functional variation in VEGF is not associated with type 2 diabetes in a United Kingdom Caucasian population. by Freathy, R, Weedon, M, Shields, B, Hitman, G, Walker, M, McCarthy, M, Hattersley, A, Frayling, T

Assessing the combined impact of 18 common genetic variants of modest effect sizes on type 2 diabetes risk. by Lango, H, Palmer, C, Morris, A, Zeggini, E, Hattersley, A, McCarthy, M, Frayling, T, Weedon, M

A large-scale association analysis of common variation of the HNF1alpha gene with type 2 diabetes in the U.K. Caucasian population. by Weedon, M, Owen, K, Shields, B, Hitman, G, Walker, M, McCarthy, M, Hattersley, A, Frayling, T

Common variations in the ALMS1 gene do not contribute to susceptibility to type 2 diabetes in a large white UK population. by Patel, S, Minton, J, Weedon, M, Frayling, T, Ricketts, C, Hitman, G, McCarthy, M, Hattersley, A, Walker, M, Barrett, T

The functional "KL-VS" variant of KLOTHO is not associated with type 2 diabetes in 5028 UK Caucasians by Freathy, R, Weedon, M, Melzer, D, Shields, B, Hitman, G, Walker, M, McCarthy, M, Hattersley, A, Frayling, T

Genetic variation in the small heterodimer partner gene and young-onset type 2 diabetes, obesity, and birth weight in U.K. subjects. by Mitchell, S, Weedon, M, Owen, K, Shields, B, Wilkins-Wall, B, Walker, M, McCarthy, M, Frayling, T, Hattersley, A

Sequencing PDX1 (insulin promoter factor 1) in 1788 UK individuals found 5% had a low frequency coding variant, but these variants are not associated with Type 2 diabetes. by Edghill, E, Khamis, A, Weedon, M, Walker, M, Hitman, G, McCarthy, M, Owen, K, Ellard, S, T Hattersley, A, Frayling, T

Assessment of the role of common genetic variation in the transient neonatal diabetes mellitus (TNDM) region in type 2 diabetes: a comparative genomic and tagging single nucleotide... by Gloyn, A, Mackay, D, Weedon, M, McCarthy, M, Walker, M, Hitman, G, Knight, B, Owen, K, Hattersley, A, Frayling, T

Type 2 diabetes transcription factor 7-like 2 (TCF7L2) risk alleles reduce beta-cell function and increase birth weight by Freathy, R, Weedon, M, McCarthy, M, Walker, M, Hitman, G, Ring, S, Ben-Shlomo, Y, Smith, G, Hattersley, A, Frayling, T

Association analysis of 6,736 U.K. subjects provides replication and confirms TCF7L2 as a type 2 diabetes susceptibility gene with a substantial effect on individual risk. by Groves, C, Zeggini, E, Minton, J, Frayling, T, Weedon, M, Rayner, N, Hitman, G, Walker, M, Wiltshire, S, Hattersley, A, McCarthy, M

Assessment of the role of genetic variation in the transient neonatal diabetes (TNDM) region on chromosome 6q24 in type 2 diabetes: a comparative genomic and haplotype approach by Gloyn, A, MacKay, D, Weedon, M, McCarthy, M, Walker, M, Hitman, G, Sampson, M, Knight, B, Hattersley, A, Frayling, T

Large scale case-control and family-based analyses of TCF7L2 variants in > 6000 UK subjects demonstrates an almost two-fold difference in relative risk between homozygote classe... by Groves, C, Zeggini, E, Minton, J, Frayling, T, Weedon, M, Rayner, N, Hitman, G, Walker, M, Wiltshire, S, Hattersley, A, McCarthy, M

Common variants of the hepatocyte nuclear factor-4alpha P2 promoter are associated with type 2 diabetes in the U.K. population. by Weedon, M, Owen, K, Shields, B, Hitman, G, Walker, M, McCarthy, M, Love-Gregory, L, Permutt, M, Hattersley, A, Frayling, T

Combining information from common type 2 diabetes risk polymorphisms improves disease prediction. by Weedon, M, McCarthy, M, Hitman, G, Walker, M, Groves, C, Zeggini, E, Rayner, N, Shields, B, Owen, K, Hattersley, A, Frayling, T

Development and validation of multivariable clinical diagnostic models to identify type 1 diabetes requiring rapid insulin therapy in adults aged 18-50 years by Lynam, A, McDonald, T, Hill, A, Dennis, J, Oram, R, Pearson, E, Weedon, M, Hattersley, A, Owen, KR, Shields, B, Jones, A

Combining information from common type 2 diabetes risk polymorphisms improves disease prediction by Weedon, M, McCarthy, M, Hitman, G, Walker, M, Groves, C, Zeggini, E, Rayner, N, Shields, B, Owen, K, Hattersley, A, Frayling, T

Common variants of the novel type 2 diabetes genes CDKAL1 and HHEX/IDE are associated with decreased pancreatic beta-cell function. by Pascoe, L, Tura, A, Patel, S, Ibrahim, I, Ferrannini, E, Zeggini, E, Weedon, M, Mari, A, Hattersley, A, McCarthy, M, Frayling, T, Walker, M