A robust clustering algorithm for identifying problematic samples in genome-wide association studies by Bellenguez, C, Strange, A, Freeman, C, Wellcome Trust Case Control Consortium 2, Donnelly, P, Spencer, C

Comparison of methods to account for relatedness in genome-wide association studies with family-based data. by Jakris Eu-Ahsunthornwattana, E Nancy Miller, Michaela Fakiola, Wellcome Trust Case Control Consortium 2, Selma M B Jeronimo, Jenefer M Blackwell, Heather J Cordell

Get full text

Genetic variation in VAC14 is associated with bacteremia secondary to diverse pathogens in African children by Gilchrist, J, Mentzer, A, Rautanen, A, Pirinen, M, Mwarumba, S, Njuguna, P, Mturi, N, Wellcome Trust Case-Control Consortium 2, Kenyan Bacteraemia Study Group, Williams, T, Scott, J, Hill, A

Genome-wide association study of intraocular pressure identifies the GLCCI1/ICA1 region as a glaucoma susceptibility locus. by Blue Mountains Eye Study (BMES), Wellcome Trust Case Control Consortium 2 (WTCCC2), Strange, A, Bellenguez, C, Freeman, C, Pirinen, M, Su, Z, Band, G, Pearson, R, Vukcevic, D, Rautanen, A, Spencer, C, Donnelly, P

A "candidate-interactome" aggregate analysis of genome-wide association data in multiple sclerosis. by Rosella Mechelli, Renato Umeton, Claudia Policano, Viviana Annibali, Giulia Coarelli, Vito A G Ricigliano, Danila Vittori, Arianna Fornasiero, Maria Chiara Buscarinu, International Multiple Sclerosis Genetics Consortium, Wellcome Trust Case Control Consortium,2, Silvia Romano, Marco Salvetti, Giovanni Ristori

Get full text

Human genetic and metabolite variation reveals that methylthioadenosine is a prognostic biomarker and an inflammatory regulator in sepsis by Wang, L, Ko, E, Gilchrist, J, Pittman, K, Rautanen, A, Pirinen, M, Thompson, J, Dubois, L, Langley, R, Jaslow, S, Salinas, R, Rouse, D, Moseley, M, Mwarumba, S, Njuguna, P, Mturi, N, Wellcome Trust Case Control Consortium 2, Kenyan Bacteraemia Study Group, Williams, T, Scott, J, Hill, A, Woods, C, Ginsburg, G, Tsalik, E, Ko, D

Serum iron levels and the risk of Parkinson disease: a Mendelian randomization study. by Irene Pichler, Fabiola Del Greco M, Martin Gögele, Christina M Lill, Lars Bertram, Chuong B Do, Nicholas Eriksson, Tatiana Foroud, Richard H Myers, PD GWAS Consortium, Michael Nalls, Margaux F Keller, International Parkinson's Disease Genomics Consortium, Wellcome Trust Case Control Consortium 2, Beben Benyamin, John B Whitfield, Genetics of Iron Status Consortium, Peter P Pramstaller, Andrew A Hicks, John R Thompson, Cosetta Minelli

Get full text

Association of genetic markers with CSF oligoclonal bands in multiple sclerosis patients. by Maurizio A Leone, Nadia Barizzone, Federica Esposito, Ausiliatrice Lucenti, Hanne F Harbo, An Goris, Ingrid Kockum, Annette Bang Oturai, Elisabeth Gulowsen Celius, Inger L Mero, Bénédicte Dubois, Tomas Olsson, Helle Bach Søndergaard, Daniele Cusi, Sara Lupoli, Bettina Kulle Andreassen, International Multiple Sclerosis Genetics Consortium, Wellcome Trust Case Control Consortium 2, Kjell-Morten Myhr, Franca R Guerini, PROGEMUS Group, PROGRESSO Group, Giancarlo Comi, Filippo Martinelli-Boneschi, Sandra D'Alfonso

Get full text

Use of schizophrenia and bipolar disorder polygenic risk scores to identify psychotic disorders by Calafato, MS, Thygesen, JH, Ranlund, S, Zartaloudi, E, Cahn, W, Crespo-Facorro, B, Díez-Revuelta, Á, Di Forti, M, Genetic Risk And Outcome Of Psychosis (Group) Consortium, Hall, M-H, Iyegbe, C, Jablensky, A, Kahn, R, Kalaydjieva, L, Kravariti, E, Lin, K, McDonald, C, McIntosh, AM, McQuillin, A, Psychosis Endophenotypes International Consortium (PEIC), Picchioni, M, Rujescu, D, Shaikh, M, Toulopoulou, T, Os, JV, Vassos, E, Walshe, M, Powell, J, Lewis, CM, Murray, RM, Bramon, E, Wellcome Trust Case Control Consortium 2 (WTCCC2)

Insights into the genetic architecture of early stage age-related macular degeneration: a genome-wide association study meta-analysis. by Elizabeth G Holliday, Albert V Smith, Belinda K Cornes, Gabriëlle H S Buitendijk, Richard A Jensen, Xueling Sim, Thor Aspelund, Tin Aung, Paul N Baird, Eric Boerwinkle, Ching Yu Cheng, Cornelia M van Duijn, Gudny Eiriksdottir, Vilmundur Gudnason, Tamara Harris, Alex W Hewitt, Michael Inouye, Fridbert Jonasson, Barbara E K Klein, Lenore Launer, Xiaohui Li, Gerald Liew, Thomas Lumley, Patrick McElduff, Barbara McKnight, Paul Mitchell, Bruce M Psaty, Elena Rochtchina, Jerome I Rotter, Rodney J Scott, Wanting Tay, Kent Taylor, Yik Ying Teo, André G Uitterlinden, Ananth Viswanathan, Sophia Xie, Wellcome Trust Case Control Consortium 2, Johannes R Vingerling, Caroline C W Klaver, E Shyong Tai, David Siscovick, Ronald Klein, Mary Frances Cotch, Tien Y Wong, John Attia, Jie Jin Wang

Get full text

Author Correction: Cross-ancestry genome-wide association analysis of corneal thickness strengthens link between complex and Mendelian eye diseases by Iglesias, AI, Mishra, A, Vitart, V, Bykhovskaya, Y, Höhn, R, Springelkamp, H, Cuellar-Partida, G, Gharahkhani, P, Bailey, JNC, Willoughby, CE, Li, X, Yazar, S, Nag, A, Khawaja, AP, Polašek, O, Siscovick, D, Mitchell, P, Tham, YC, Haines, JL, Kearns, LS, Hayward, C, Shi, Y, Van Leeuwen, EM, Taylor, KD, Blue Mountains Eye Study - Gwas Group, Bonnemaijer, P, Rotter, JI, Martin, NG, Zeller, T, Mills, RA, Souzeau, E, Staffieri, SE, Jonas, JB, Schmidtmann, I, Boutin, T, Kang, JH, Lucas, SEM, Wong, TY, Beutel, ME, Wilson, JF, Wellcome Trust Case Control Consortium 2 (Wtccc2), Neighborhood Consortium, Uitterlinden, AG, Vithana, EN, Foster, PJ, Hysi, PG, Hewitt, AW, Khor, CC, Pasquale, LR, Montgomery, GW, Klaver, CCW, Aung, T, Pfeiffer, N, Mackey, DA, Hammond, CJ, Cheng, C-Y, Craig, JE, Rabinowitz, YS, Wiggs, JL, Burdon, KP, Van Duijn, CM, Macgregor, S

Genome-wide association studies in oesophageal adenocarcinoma and Barrett's oesophagus: a large-scale meta-analysis. by Gharahkhani, P, Fitzgerald, R, Vaughan, T, Palles, C, Gockel, I, Tomlinson, I, Buas, M, May, A, Gerges, C, Anders, M, Becker, J, Kreuser, N, Noder, T, Venerito, M, Veits, L, Schmidt, T, Manner, H, Schmidt, C, Hess, T, Böhmer, A, Izbicki, J, Hölscher, A, Lang, H, Lorenz, D, Schumacher, B, Hackelsberger, A, Mayershofer, R, Pech, O, Vashist, Y, Ott, K, Vieth, M, Weismüller, J, Nöthen, M, Barrett's and Esophageal Adenocarcinoma Consortium (BEACON), Esophageal Adenocarcinoma GenEtics Consortium (EAGLE), Wellcome Trust Case Control Consortium 2 (WTCCC2), Attwood, S, Barr, H, Chegwidden, L, de Caestecker, J, Harrison, R, Love, S, MacDonald, D, Moayyedi, P, Prenen, H, Watson, R, Iyer, P, Anderson, L, Bernstein, L, Chow, W, Hardie, L, Lagergren, J, Liu, G, Risch, H, Wu, A, Ye, W, Bird, N, Shaheen, N, Gammon, M, Corley, D, Caldas, C, Moebus, S, Knapp, M, Peters, W, Neuhaus, H, Rösch, T, Ell, C, MacGregor, S, Pharoah, P, Whiteman, D, Jankowski, J, Schumacher, J

Common genetic determinants of intraocular pressure and primary open-angle glaucoma. by Leonieke M E van Koolwijk, Wishal D Ramdas, M Kamran Ikram, Nomdo M Jansonius, Francesca Pasutto, Pirro G Hysi, Stuart Macgregor, Sarah F Janssen, Alex W Hewitt, Ananth C Viswanathan, Jacoline B ten Brink, S Mohsen Hosseini, Najaf Amin, Dominiek D G Despriet, Jacqueline J M Willemse-Assink, Rogier Kramer, Fernando Rivadeneira, Maksim Struchalin, Yurii S Aulchenko, Nicole Weisschuh, Matthias Zenkel, Christian Y Mardin, Eugen Gramer, Ulrich Welge-Lüssen, Grant W Montgomery, Francis Carbonaro, Terri L Young, DCCT/EDIC Research Group, Céline Bellenguez, Peter McGuffin, Paul J Foster, Fotis Topouzis, Paul Mitchell, Jie Jin Wang, Tien Y Wong, Monika A Czudowska, Albert Hofman, Andre G Uitterlinden, Roger C W Wolfs, Paulus T V M de Jong, Ben A Oostra, Andrew D Paterson, Wellcome Trust Case Control Consortium 2, David A Mackey, Arthur A B Bergen, André Reis, Christopher J Hammond, Johannes R Vingerling, Hans G Lemij, Caroline C W Klaver, Cornelia M van Duijn

Get full text

Genetic loci for retinal arteriolar microcirculation. by Xueling Sim, Richard A Jensen, M Kamran Ikram, Mary Frances Cotch, Xiaohui Li, Stuart MacGregor, Jing Xie, Albert Vernon Smith, Eric Boerwinkle, Paul Mitchell, Ronald Klein, Barbara E K Klein, Nicole L Glazer, Thomas Lumley, Barbara McKnight, Bruce M Psaty, Paulus T V M de Jong, Albert Hofman, Fernando Rivadeneira, Andre G Uitterlinden, Cornelia M van Duijn, Thor Aspelund, Gudny Eiriksdottir, Tamara B Harris, Fridbert Jonasson, Lenore J Launer, Wellcome Trust Case Control Consortium 2, John Attia, Paul N Baird, Stephen Harrap, Elizabeth G Holliday, Michael Inouye, Elena Rochtchina, Rodney J Scott, Ananth Viswanathan, Global BPGen Consortium, Guo Li, Nicholas L Smith, Kerri L Wiggins, Jane Z Kuo, Kent D Taylor, Alex W Hewitt, Nicholas G Martin, Grant W Montgomery, Cong Sun, Terri L Young, David A Mackey, Natalie R van Zuydam, Alex S F Doney, Colin N A Palmer, Andrew D Morris, Jerome I Rotter, E Shyong Tai, Vilmundur Gudnason, Johannes R Vingerling, David S Siscovick, Jie Jin Wang, Tien Y Wong

Get full text

Author Correction: Cross-ancestry genome-wide association analysis of corneal thickness strengthens link between complex and Mendelian eye diseases by Adriana I. Iglesias, Aniket Mishra, Veronique Vitart, Yelena Bykhovskaya, René Höhn, Henriët Springelkamp, Gabriel Cuellar-Partida, Puya Gharahkhani, Jessica N. Cooke Bailey, Colin E. Willoughby, Xiaohui Li, Seyhan Yazar, Abhishek Nag, Anthony P. Khawaja, Ozren Polašek, David Siscovick, Paul Mitchell, Yih Chung Tham, Jonathan L. Haines, Lisa S. Kearns, Caroline Hayward, Yuan Shi, Elisabeth M. van Leeuwen, Kent D. Taylor, Blue Mountains Eye Study - GWAS group, Pieter Bonnemaijer, Jerome I. Rotter, Nicholas G. Martin, Tanja Zeller, Richard A. Mills, Emmanuelle Souzeau, Sandra E. Staffieri, Jost B. Jonas, Irene Schmidtmann, Thibaud Boutin, Jae H. Kang, Sionne E. M. Lucas, Tien Yin Wong, Manfred E. Beutel, James F. Wilson, Wellcome Trust Case Control Consortium 2 (WTCCC2), NEIGHBORHOOD consortium, André G. Uitterlinden, Eranga N. Vithana, Paul J. Foster, Pirro G. Hysi, Alex W. Hewitt, Chiea Chuen Khor, Louis R. Pasquale, Grant W. Montgomery, Caroline C. W. Klaver, Tin Aung, Norbert Pfeiffer, David A. Mackey, Christopher J. Hammond, Ching-Yu Cheng, Jamie E. Craig, Yaron S. Rabinowitz, Janey L. Wiggs, Kathryn P. Burdon, Cornelia M. van Duijn, Stuart MacGregor

Get full text

Cross-ancestry genome-wide association analysis of corneal thickness strengthens link between complex and Mendelian eye diseases by Adriana I. Iglesias, Aniket Mishra, Veronique Vitart, Yelena Bykhovskaya, René Höhn, Henriët Springelkamp, Gabriel Cuellar-Partida, Puya Gharahkhani, Jessica N. Cooke Bailey, Colin E. Willoughby, Xiaohui Li, Seyhan Yazar, Abhishek Nag, Anthony P. Khawaja, Ozren Polašek, David Siscovick, Paul Mitchell, Yih Chung Tham, Jonathan L. Haines, Lisa S. Kearns, Caroline Hayward, Yuan Shi, Elisabeth M. van Leeuwen, Kent D. Taylor, Blue Mountains Eye Study—GWAS group, Pieter Bonnemaijer, Jerome I. Rotter, Nicholas G. Martin, Tanja Zeller, Richard A. Mills, Emmanuelle Souzeau, Sandra E. Staffieri, Jost B. Jonas, Irene Schmidtmann, Thibaud Boutin, Jae H. Kang, Sionne E. M. Lucas, Tien Yin Wong, Manfred E. Beutel, James F. Wilson, NEIGHBORHOOD Consortium, Wellcome Trust Case Control Consortium 2 (WTCCC2), André G. Uitterlinden, Eranga N. Vithana, Paul J. Foster, Pirro G. Hysi, Alex W. Hewitt, Chiea Chuen Khor, Louis R. Pasquale, Grant W. Montgomery, Caroline C. W. Klaver, Tin Aung, Norbert Pfeiffer, David A. Mackey, Christopher J. Hammond, Ching-Yu Cheng, Jamie E. Craig, Yaron S. Rabinowitz, Janey L. Wiggs, Kathryn P. Burdon, Cornelia M. van Duijn, Stuart MacGregor

Get full text

Genome-wide association and functional follow-up reveals new loci for kidney function. by Cristian Pattaro, Anna Köttgen, Alexander Teumer, Maija Garnaas, Carsten A Böger, Christian Fuchsberger, Matthias Olden, Ming-Huei Chen, Adrienne Tin, Daniel Taliun, Man Li, Xiaoyi Gao, Mathias Gorski, Qiong Yang, Claudia Hundertmark, Meredith C Foster, Conall M O'Seaghdha, Nicole Glazer, Aaron Isaacs, Ching-Ti Liu, Albert V Smith, Jeffrey R O'Connell, Maksim Struchalin, Toshiko Tanaka, Guo Li, Andrew D Johnson, Hinco J Gierman, Mary Feitosa, Shih-Jen Hwang, Elizabeth J Atkinson, Kurt Lohman, Marilyn C Cornelis, Åsa Johansson, Anke Tönjes, Abbas Dehghan, Vincent Chouraki, Elizabeth G Holliday, Rossella Sorice, Zoltan Kutalik, Terho Lehtimäki, Tõnu Esko, Harshal Deshmukh, Sheila Ulivi, Audrey Y Chu, Federico Murgia, Stella Trompet, Medea Imboden, Barbara Kollerits, Giorgio Pistis, CARDIoGRAM Consortium, ICBP Consortium, CARe Consortium, Wellcome Trust Case Control Consortium 2 (WTCCC2), Tamara B Harris, Lenore J Launer, Thor Aspelund, Gudny Eiriksdottir, Braxton D Mitchell, Eric Boerwinkle, Helena Schmidt, Margherita Cavalieri, Madhumathi Rao, Frank B Hu, Ayse Demirkan, Ben A Oostra, Mariza de Andrade, Stephen T Turner, Jingzhong Ding, Jeanette S Andrews, Barry I Freedman, Wolfgang Koenig, Thomas Illig, Angela Döring, H-Erich Wichmann, Ivana Kolcic, Tatijana Zemunik, Mladen Boban, Cosetta Minelli, Heather E Wheeler, Wilmar Igl, Ghazal Zaboli, Sarah H Wild, Alan F Wright, Harry Campbell, David Ellinghaus, Ute Nöthlings, Gunnar Jacobs, Reiner Biffar, Karlhans Endlich, Florian Ernst, Georg Homuth, Heyo K Kroemer, Matthias Nauck, Sylvia Stracke, Uwe Völker, Henry Völzke, Peter Kovacs, Michael Stumvoll, Reedik Mägi, Albert Hofman, Andre G Uitterlinden, Fernando Rivadeneira, Yurii S Aulchenko, Ozren Polasek, Nick Hastie, Veronique Vitart, Catherine Helmer, Jie Jin Wang, Daniela Ruggiero, Sven Bergmann, Mika Kähönen, Jorma Viikari, Tiit Nikopensius, Michael Province, Shamika Ketkar, Helen Colhoun, Alex Doney, Antonietta Robino, Franco Giulianini, Bernhard K Krämer, Laura Portas, Ian Ford, Brendan M Buckley, Martin Adam, Gian-Andri Thun, Bernhard Paulweber, Margot Haun, Cinzia Sala, Marie Metzger, Paul Mitchell, Marina Ciullo, Stuart K Kim, Peter Vollenweider, Olli Raitakari, Andres Metspalu, Colin Palmer, Paolo Gasparini, Mario Pirastu, J Wouter Jukema, Nicole M Probst-Hensch, Florian Kronenberg, Daniela Toniolo, Vilmundur Gudnason, Alan R Shuldiner, Josef Coresh, Reinhold Schmidt, Luigi Ferrucci, David S Siscovick, Cornelia M van Duijn, Ingrid Borecki, Sharon L R Kardia, Yongmei Liu, Gary C Curhan, Igor Rudan, Ulf Gyllensten, James F Wilson, Andre Franke, Peter P Pramstaller, Rainer Rettig, Inga Prokopenko, Jacqueline C M Witteman, Caroline Hayward, Paul Ridker, Afshin Parsa, Murielle Bochud, Iris M Heid, Wolfram Goessling, Daniel I Chasman, W H Linda Kao, Caroline S Fox

Get full text