Whitehead Institute

Whitehead Institute for Biomedical Research is a non-profit research institute located in Cambridge, Massachusetts, United States that is dedicated to improving human health through basic biomedical research. It was founded as a fiscally independent entity from the Massachusetts Institute of Technology (MIT), where its 19 members all hold faculty appointments in the MIT Department of Biology or the MIT Department of Bioengineering. , Ruth Lehmann is its director; she succeeded David C. Page. Provided by Wikipedia
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  1. 1
    Susan Lindquist: Visionary scientist and peerless mentor

    Susan Lindquist: Visionary scientist and peerless mentor by Bevis, Brooke J.

    Published 2017
    Other Authors: “…Whitehead Institute for Biomedical Research…”
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  2. 2
    An RNA nanoparticle vaccine against Zika virus elicits antibody and CD8+ T cell responses in a mouse model

    An RNA nanoparticle vaccine against Zika virus elicits antibody and CD8+ T cell responses in a mouse model by Woodham, Andrew W., Chahal, Jasdave, Fang, Taotao, Khan, Omar Fizal, Ling, Jingjing, Anderson, Daniel Griffith, Ploegh, Hidde

    Published 2017
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  3. 3
    Non-specific activities of the major herbicide-resistance gene BAR

    Non-specific activities of the major herbicide-resistance gene BAR by Christ, Bastien, Hochstrasser, Ramon, Guyer, Luzia, Francisco, Rita, Aubry, Sylvain, Hörtensteiner, Stefan, Weng, Jing-Ke

    Published 2018
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  4. 4
    Whsc1 links pluripotency exit with mesendoderm specification

    Whsc1 links pluripotency exit with mesendoderm specification by Tian, Tian V., Di Stefano, Bruno, Stik, Grégoire, Vila-Casadesús, Maria, Sardina, José Luis, Vidal, Enrique, Dasti, Alessandro, Segura-Morales, Carolina, De Andrés-Aguayo, Luisa, Gómez, Antonio, Goldmann, Johanna, Jaenisch, Rudolf, Graf, Thomas

    Published 2019
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  5. 5
    Transcription Factors Activate Genes through the Phase-Separation Capacity of Their Activation Domains

    Transcription Factors Activate Genes through the Phase-Separation Capacity of Their Activation Domains by Klein, Isaac A., Sabari, Benjamin R., Dall’Agnese, Alessandra, Coffey, Eliot L., Zamudio, Alicia V., Manteiga, John C., Hannett, Nancy M., Abraham, Brian J., Afeyan, Lena K., Guo, Yang E., Schuijers, Jurian, Lee, Tong Ihn, Taatjes, Dylan J., Young, Richard A., Shrinivas, Krishna,Ph. D.Massachusetts Institute of Technology., Li, Charles H.

    Published 2020
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  6. 6
    Firefly genomes illuminate parallel origins of bioluminescence in beetles

    Firefly genomes illuminate parallel origins of bioluminescence in beetles by Fallon, Timothy R, Weng, Jing-Ke

    Published 2020
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  7. 7
    ASCL1 is a MYCN- and LMO1-dependent member of the adrenergic neuroblastoma core regulatory circuitry

    ASCL1 is a MYCN- and LMO1-dependent member of the adrenergic neuroblastoma core regulatory circuitry by Durbin, Adam D., Abraham, Brian J., Lawton, Lee N., Young, Richard A., Sanda, Takaomi

    Published 2020
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  8. 8
    Basal constriction during midbrain–hindbrain boundary morphogenesis is mediated by Wnt5b and focal adhesion kinase

    Basal constriction during midbrain–hindbrain boundary morphogenesis is mediated by Wnt5b and focal adhesion kinase by Gutzman, Jennifer H., Graeden, Ellie, Brachmann, Isabel, Sive, Hazel

    Published 2020
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  9. 9
    The Reference Genome Sequence of Scutellaria baicalensis Provides Insights into the Evolution of Wogonin Biosynthesis

    The Reference Genome Sequence of Scutellaria baicalensis Provides Insights into the Evolution of Wogonin Biosynthesis by Weng, Jing-Ke, Pluskal, Tomáš

    Published 2020
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  10. 10
    Nutrient mTORC1 signaling underpins regulatory T cell control of immune tolerance

    Nutrient mTORC1 signaling underpins regulatory T cell control of immune tolerance by Efeyan, Alejo, Sabatini, David M.

    Published 2020
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  11. 11
    Activation of PASK by mTORC1 is required for the onset of the terminal differentiation program

    Activation of PASK by mTORC1 is required for the onset of the terminal differentiation program by Kang, Seong Anthony Woo, Sabatini, David M.

    Published 2020
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  12. 12
    The biosynthetic origin of psychoactive kavalactones in kava

    The biosynthetic origin of psychoactive kavalactones in kava by Pluskal, Tomáš, Torrens-Spence, Michael P., Fallon, Timothy R., De Abreu, Andrea, Shi, Cindy H., Weng, Jing-Ke

    Published 2020
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  13. 13
    DEPTOR modulates activation responses in CD4+ T cells and enhances immunoregulation following transplantation

    DEPTOR modulates activation responses in CD4+ T cells and enhances immunoregulation following transplantation by Sabatini, David M.

    Published 2020
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  14. 14
    SFXN1 is a mitochondrial serine transporter required for one-carbon metabolism

    SFXN1 is a mitochondrial serine transporter required for one-carbon metabolism by Kory, Nora, Wyant, Gregory A., Prakash, Gyan, De Bos, Jelmi uit, Pacold, Michael E., Chan, Sze Ham, Lewis, Caroline A., Wang, Tim, Keys, Heather R., Sabatini, David M.

    Published 2020
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  15. 15
    Serine Catabolism by SHMT2 Is Required for Proper Mitochondrial Translation Initiation and Maintenance of Formylmethionyl-tRNAs

    Serine Catabolism by SHMT2 Is Required for Proper Mitochondrial Translation Initiation and Maintenance of Formylmethionyl-tRNAs by Sabatini, David M.

    Published 2020
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  16. 16
    Repeated evolution of cytochrome P450-mediated spiroketal steroid biosynthesis in plants

    Repeated evolution of cytochrome P450-mediated spiroketal steroid biosynthesis in plants by Christ, Bastien, Xu, Chengchao, Xu, Menglong, Li, Fu-Shuang, Mitchell, Andrew J., Weng, Jing-Ke

    Published 2020
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  17. 17
    Identification of a cancer stem cell-specific function for the histone deacetylases, HDAC1 and HDAC7, in breast and ovarian cancer

    Identification of a cancer stem cell-specific function for the histone deacetylases, HDAC1 and HDAC7, in breast and ovarian cancer by Lee, T. I., Cohick, E. B., Gropper, A. B., Young, R. A.

    Published 2020
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  18. 18
    NUFIP1 is a ribosome receptor for starvation-induced ribophagy

    NUFIP1 is a ribosome receptor for starvation-induced ribophagy by Wyant, Gregory A., Abu-Remaileh, Monther, Frenkel, Evgeni M., Laqtom, Nouf N., Dharamdasani, Vimisha, Lewis, Caroline A., Chan, Sze Ham, Sabatini, David M.

    Published 2020
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  19. 19
    Fasting Activates Fatty Acid Oxidation to Enhance Intestinal Stem Cell Function during Homeostasis and Aging

    Fasting Activates Fatty Acid Oxidation to Enhance Intestinal Stem Cell Function during Homeostasis and Aging by Mihaylova, Maria M., Cheng, Chia-Wei, Cao, Amanda Q., Tripathi, Surya, Mana, Miyeko D., Bauer-Rowe, Khristian E., Abu-Remaileh, Monther, Clavain, Laura, Erdemir, Aysegul, Lewis, Caroline A., Freinkman, Elizaveta, Huang, Yanmei, Bell, George W., Sabatini, David M., Yilmaz, Ömer H.

    Published 2020
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  20. 20
    A mouse model of DEPDC5-related epilepsy: Neuronal loss of Depdc5 causes dysplastic and ectopic neurons, increased mTOR signaling, and seizure susceptibility

    A mouse model of DEPDC5-related epilepsy: Neuronal loss of Depdc5 causes dysplastic and ectopic neurons, increased mTOR signaling, and seizure susceptibility by Wolfson, Rachel L., Sabatini, David M.

    Published 2020
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