PPE38-Secretion-Dependent Proteins of M. tuberculosis Alter NF-kB Signalling and Inflammatory Responses in Macrophages by James Gallant, James Gallant, Tiaan Heunis, Tiaan Heunis, Caroline Beltran, Karin Schildermans, Sven Bruijns, Inge Mertens, Wilbert Bitter, Wilbert Bitter, Samantha L. Sampson

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New Insights into the Regulation of Cell-Surface Signaling Activity Acquired from a Mutagenesis Screen of the Pseudomonas putida IutY Sigma/Anti-Sigma Factor by María A. Llamas, Karlijn C. Bastiaansen, Karlijn C. Bastiaansen, Cristina Civantos, Wilbert Bitter

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Phagosomal rupture by Mycobacterium tuberculosis results in toxicity and host cell death. by Roxane Simeone, Alexandre Bobard, Juliane Lippmann, Wilbert Bitter, Laleh Majlessi, Roland Brosch, Jost Enninga

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Mutagenesis-Based Characterization and Improvement of a Novel Inclusion Body Tag by Wouter S. P. Jong, Wouter S. P. Jong, Corinne M. ten Hagen-Jongman, David Vikström, Wendy Dontje, Abdallah M. Abdallah, Abdallah M. Abdallah, Jan-Willem de Gier, Wilbert Bitter, Wilbert Bitter, Joen Luirink, Joen Luirink

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Optimization of secretion and surface localization of heterologous OVA protein in mycobacteria by using LipY as a carrier by Maroeska J. Burggraaf, Louis S. Ates, Alexander Speer, Kim van der Kuij, Coen Kuijl, Wilbert Bitter

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Functional dissection of the PE domain responsible for translocation of PE_PGRS33 across the mycobacterial cell wall. by Alessandro Cascioferro, Maria H Daleke, Marcello Ventura, Valentina Donà, Giovanni Delogu, Giorgio Palù, Wilbert Bitter, Riccardo Manganelli

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Stapling of Peptides Potentiates the Antibiotic Treatment of <em>Acinetobacter baumannii</em> In Vivo by Gina K. Schouten, Felix M. Paulussen, Oscar P. Kuipers, Wilbert Bitter, Tom N. Grossmann, Peter van Ulsen

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A flat embedding method for transmission electron microscopy reveals an unknown mechanism of tetracycline by Michaela Wenzel, Marien P. Dekker, Biwen Wang, Maroeska J. Burggraaf, Wilbert Bitter, Jan R. T. van Weering, Leendert W. Hamoen

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Mycobacterium tuberculosis β-lactamase variant reduces sensitivity to ampicillin/avibactam in a zebrafish-Mycobacterium marinum model of tuberculosis by Ilona van Alen, Mayra A. Aguirre García, Janneke J. Maaskant, Coenraad P. Kuijl, Wilbert Bitter, Annemarie H. Meijer, Marcellus Ubbink

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Type VII Secretion Substrates of Pathogenic Mycobacteria Are Processed by a Surface Protease by Maroeska J. Burggraaf, Alexander Speer, Aniek S. Meijers, Roy Ummels, Astrid M. van der Sar, Konstantin V. Korotkov, Wilbert Bitter, Coenraad Kuijl

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An anti-tuberculosis compound screen using a zebrafish infection model identifies an aspartyl-tRNA synthetase inhibitor by Eva Habjan, Vien Q. T. Ho, James Gallant, Gunny van Stempvoort, Kin Ki Jim, Coen Kuijl, Daan P. Geerke, Wilbert Bitter, Alexander Speer

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The Prc and CtpA proteases modulate cell-surface signaling activity and virulence in Pseudomonas aeruginosa by Joaquín R. Otero-Asman, Ana Sánchez-Jiménez, Karlijn C. Bastiaansen, Sarah Wettstadt, Cristina Civantos, Alicia García-Puente, Wilbert Bitter, María A. Llamas

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Mycosins Are Required for the Stabilization of the ESX-1 and ESX-5 Type VII Secretion Membrane Complexes by Vincent J. C. van Winden, Roy Ummels, Sander R. Piersma, Connie R. Jiménez, Konstantin V. Korotkov, Wilbert Bitter, Edith N. G. Houben

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Dysregulation of <i>Mycobacterium marinum</i> ESX-5 Secretion by Novel 1,2,4-oxadiazoles by Vien Q. T. Ho, Mark K. Rong, Eva Habjan, Samantha D. Bommer, Thang V. Pham, Sander R. Piersma, Wilbert Bitter, Eelco Ruijter, Alexander Speer

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Identification of a Novel Conjugative Plasmid in Mycobacteria That Requires Both Type IV and Type VII Secretion by Roy Ummels, Abdallah M. Abdallah, Vincent Kuiper, Anouar Aâjoud, Marion Sparrius, Raeece Naeem, Herman P. Spaink, Dick van Soolingen, Arnab Pain, Wilbert Bitter

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The ESX-1 Substrate PPE68 Has a Key Function in ESX-1-Mediated Secretion in Mycobacterium marinum by Merel P. M. Damen, Aniek S. Meijers, Esther M. Keizer, Sander R. Piersma, Connie R. Jiménez, Coenraad P. Kuijl, Wilbert Bitter, Edith N. G. Houben

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Cell envelope stress in mycobacteria is regulated by the novel signal transduction ATPase IniR in response to trehalose. by Maikel Boot, Vincent J C van Winden, Marion Sparrius, Robert van de Weerd, Alexander Speer, Roy Ummels, Tige Rustad, David R Sherman, Wilbert Bitter

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RD5-mediated lack of PE_PGRS and PPE-MPTR export in BCG vaccine strains results in strong reduction of antigenic repertoire but little impact on protection. by Louis S Ates, Fadel Sayes, Wafa Frigui, Roy Ummels, Merel P M Damen, Daria Bottai, Marcel A Behr, Jeroen W J van Heijst, Wilbert Bitter, Laleh Majlessi, Roland Brosch

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Comparative Genomic and Transcriptomic Analyses of Mycobacterium kansasii Subtypes Provide New Insights Into Their Pathogenicity and Taxonomy by Qingtian Guan, Roy Ummels, Fathia Ben-Rached, Yara Alzahid, Mohammad S. Amini, Sabir A. Adroub, Jakko van Ingen, Wilbert Bitter, Abdallah M. Abdallah, Abdallah M. Abdallah, Arnab Pain, Arnab Pain

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Impact of protein domains on PE_PGRS30 polar localization in Mycobacteria. by Flavio De Maio, Giuseppe Maulucci, Mariachiara Minerva, Saber Anoosheh, Ivana Palucci, Raffaella Iantomasi, Valentina Palmieri, Serena Camassa, Michela Sali, Maurizio Sanguinetti, Wilbert Bitter, Riccardo Manganelli, Marco De Spirito, Giovanni Delogu

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