William Schafer
William Ronald Schafer (born August 29, 1964) is a neuroscientist and geneticist who has made important contributions to understanding the molecular and neural basis of behaviour. His work, principally in the nematode ''
C. elegans'', has used an interdisciplinary approach to investigate how small groups of
neurons generate behavior, and he has pioneered methodological approaches, including
optogenetic neuroimaging and automated behavioural phenotyping, that have been widely influential in the broader neuroscience field. He has made significant discoveries on the functional properties of
ionotropic receptors in
sensory transduction and on the roles of
gap junctions and extrasynaptic
modulation in neuronal microcircuits. More recently, he has applied theoretical ideas from
network science and
control theory to investigate the structure and function of simple neuronal
connectomes, with the goal of understanding conserved computational principles in larger brains. He is an
EMBO member, Fellow of the
Academy of Medical Sciences, and
Fellow of the Royal Society.
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