Computational Methods for the Analysis of Array Comparative Genomic Hybridization by Raj Chari, William W. Lockwood, Wan L. Lam

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Computational Methods for the Analysis of Array Comparative Genomic Hybridization by Raj Chari, William W. Lockwood, Wan L. Lam

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New insights into the biology and development of lung cancer in never smokers—implications for early detection and treatment by Peiyao Wang, Sophie Sun, Stephen Lam, William W. Lockwood

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Resistance to BET inhibitors in lung adenocarcinoma is mediated by casein kinase phosphorylation of BRD4 by Jack Calder, Amy Nagelberg, Jennifer Luu, Daniel Lu, William W. Lockwood

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Emerging Molecular Dependencies of Mutant EGFR-Driven Non-Small Cell Lung Cancer by Dylan A. Farnsworth, Yankuan T. Chen, Georgia de Rappard Yuswack, William W. Lockwood

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Tandem mass tag-based thermal proteome profiling for the discovery of drug-protein interactions in cancer cells by Fraser D. Johnson, Christopher S. Hughes, Alvin Liu, William W. Lockwood, Gregg B. Morin

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Evidence that synthetic lethality underlies the mutual exclusivity of oncogenic KRAS and EGFR mutations in lung adenocarcinoma by Arun M Unni, William W Lockwood, Kreshnik Zejnullahu, Shih-Queen Lee-Lin, Harold Varmus

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Characterizing the secretome of EGFR mutant lung adenocarcinoma by Jennifer K. Luu, Jennifer K. Luu, Fraser D. Johnson, Fraser D. Johnson, Jana Jajarmi, Jana Jajarmi, Tianna Sihota, Tianna Sihota, Rocky Shi, Rocky Shi, Daniel Lu, Daniel Lu, Dylan Farnsworth, Dylan Farnsworth, Sandra E. Spencer, Gian Luca Negri, Gregg B. Morin, Gregg B. Morin, William W. Lockwood, William W. Lockwood, William W. Lockwood

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MET Exon 14 Splice-Site Mutations Preferentially Activate KRAS Signaling to Drive Tumourigenesis by Daniel Lu, Amy Nagelberg, Justine LM Chow, Yankuan T Chen, Quentin Michalchuk, Romel Somwar, William W. Lockwood

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Hyperactivation of ERK by multiple mechanisms is toxic to RTK-RAS mutation-driven lung adenocarcinoma cells by Arun M Unni, Bryant Harbourne, Min Hee Oh, Sophia Wild, John R Ferrarone, William W Lockwood, Harold Varmus

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Extracellular signal-regulated kinase mediates chromatin rewiring and lineage transformation in lung cancer by Yusuke Inoue, Ana Nikolic, Dylan Farnsworth, Rocky Shi, Fraser D Johnson, Alvin Liu, Marc Ladanyi, Romel Somwar, Marco Gallo, William W Lockwood

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MicroRNA Modification of Coxsackievirus B3 Decreases Its Toxicity, while Retaining Oncolytic Potency against Lung Cancer by Huitao Liu, Yuan Chao Xue, Haoyu Deng, Yasir Mohamud, Chen Seng Ng, Axel Chu, Chinten James Lim, William W. Lockwood, William W.G. Jia, Honglin Luo

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MicroRNA Modification of Coxsackievirus B3 Decreases Its Toxicity, while Retaining Oncolytic Potency against Lung Cancer by Huitao Liu, Yuan Chao Xue, Haoyu Deng, Yasir Mohamud, Chen Seng Ng, Axel Chu, Chinten James Lim, William W. Lockwood, William W.G. Jia, Honglin Luo

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Coxsackievirus Type B3 Is a Potent Oncolytic Virus against KRAS-Mutant Lung Adenocarcinoma by Haoyu Deng, Huitao Liu, Tanya de Silva, YuanChao Xue, Yasir Mohamud, Chen Seng Ng, Junyan Qu, Jingchun Zhang, William W.G. Jia, William W. Lockwood, Honglin Luo

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Delineating spatial cell-cell interactions in the solid tumour microenvironment through the lens of highly multiplexed imaging by David E. Cohn, Aisling Forder, Erin A. Marshall, Emily A. Vucic, Greg L. Stewart, Kouther Noureddine, William W. Lockwood, Calum E. MacAulay, Martial Guillaud, Wan L. Lam

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MEK inhibitor resistance in lung adenocarcinoma is associated with addiction to sustained ERK suppression by Dylan A. Farnsworth, Yusuke Inoue, Fraser D. Johnson, Georgia de Rappard-Yuswack, Daniel Lu, Rocky Shi, Lok In Josephine Ma, Marissa S. Mattar, Romel Somwar, Marc Ladanyi, Arun M. Unni, William W. Lockwood

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Alterations in genes of the EGFR signaling pathway and their relationship to EGFR tyrosine kinase inhibitor sensitivity in lung cancer cell lines. by Jeet Gandhi, Jianling Zhang, Yang Xie, Junichi Soh, Hisayuki Shigematsu, Wei Zhang, Hiromasa Yamamoto, Michael Peyton, Luc Girard, William W Lockwood, Wan L Lam, Marileila Varella-Garcia, John D Minna, Adi F Gazdar

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Lung adenocarcinoma of never smokers and smokers harbor differential regions of genetic alteration and exhibit different levels of genomic instability. by Kelsie L Thu, Emily A Vucic, Raj Chari, Wei Zhang, William W Lockwood, John C English, Rong Fu, Pei Wang, Ziding Feng, Calum E MacAulay, Adi F Gazdar, Stephen Lam, Wan L Lam

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Oncogene mutations, copy number gains and mutant allele specific imbalance (MASI) frequently occur together in tumor cells. by Junichi Soh, Naoki Okumura, William W Lockwood, Hiromasa Yamamoto, Hisayuki Shigematsu, Wei Zhang, Raj Chari, David S Shames, Ximing Tang, Calum MacAulay, Marileila Varella-Garcia, Tõnu Vooder, Ignacio I Wistuba, Stephen Lam, Rolf Brekken, Shinichi Toyooka, John D Minna, Wan L Lam, Adi F Gazdar

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Integrative genomic analyses identify BRF2 as a novel lineage-specific oncogene in lung squamous cell carcinoma. by William W Lockwood, Raj Chari, Bradley P Coe, Kelsie L Thu, Cathie Garnis, Chad A Malloff, Jennifer Campbell, Ariane C Williams, Dorothy Hwang, Chang-Qi Zhu, Timon P H Buys, John Yee, John C English, Calum Macaulay, Ming-Sound Tsao, Adi F Gazdar, John D Minna, Stephen Lam, Wan L Lam

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